Bending the Curve in Cardiovascular Disease Mortality Bethesda+40 and Beyond

Goff, David Calvin Jr, Khan, Sadiya Sana, Lloyd-Jones, Donald, Arnett, Donna K, Carnethon, Mercedes R, Labarthe, Darwin R, Loop, Matthew Shane, Luepker, Russell V, McConnell, Michael V, Mensah, George A
et al (show 8 more authors) (2021) Bending the Curve in Cardiovascular Disease Mortality Bethesda+40 and Beyond. CIRCULATION, 143 (8). pp. 837-851.

Access the full-text of this item by clicking on the Open Access link.


More than 40 years after the 1978 Bethesda Conference on the Declining Mortality from Coronary Heart Disease provided the scientific community with a blueprint for systematic analysis to understand declining rates of coronary heart disease, there are indications the decline has ended or even reversed despite advances in our knowledge about the condition and treatment. Recent data show a more complex situation, with mortality rates for overall cardiovascular disease, including coronary heart disease and stroke, decelerating, whereas those for heart failure are increasing. To mark the 40th anniversary of the Bethesda Conference, the National Heart, Lung, and Blood Institute and the American Heart Association cosponsored the "Bending the Curve in Cardiovascular Disease Mortality: Bethesda + 40" symposium. The objective was to examine the immediate and long-term outcomes of the 1978 conference and understand the current environment. Symposium themes included trends and future projections in cardiovascular disease (in the United States and internationally), the evolving obesity and diabetes epidemics, and harnessing emerging and innovative opportunities to preserve and promote cardiovascular health and prevent cardiovascular disease. In addition, participant-led discussion explored the challenges and barriers in promoting cardiovascular health across the lifespan and established a potential framework for observational research and interventions that would begin in early childhood (or ideally in utero). This report summarizes the relevant research, policy, and practice opportunities discussed at the symposium.

Item Type: Article
Uncontrolled Keywords: cardiovascular diseases, health promotion, longevity, primary prevention, trends
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Population Health
Depositing User: Symplectic Admin
Date Deposited: 08 Feb 2023 16:18
Last Modified: 08 Feb 2023 16:18
DOI: 10.1161/CIRCULATIONAHA.120.046501
Open Access URL:
Related URLs: