Creating 3D Objects with Integrated Electronics via Multiphoton Fabrication In Vitro and In Vivo


Baldock, Sara J, Kevin, Punarja, Harper, Garry R, Griffin, Rebecca, Genedy, Hussein H, Fong, M James, Zhao, Zhiyi, Zhang, Zijian ORCID: 0000-0002-3004-6697, Shen, Yaochun ORCID: 0000-0002-8915-1993, Lin, Hungyen et al (show 13 more authors) (2023) Creating 3D Objects with Integrated Electronics via Multiphoton Fabrication In Vitro and In Vivo. ADVANCED MATERIALS TECHNOLOGIES, 8 (11). p. 2201274.

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Abstract

<jats:title>Abstract</jats:title><jats:p>3D objects with integrated electronics are produced using an additive manufacturing approach relying on multiphoton fabrication (direct laser writing, (DLW)). Conducting polymer‐based structures (with micrometer‐millimeter scale features) are printed within exemplar matrices, including an elastomer (polydimethylsiloxane, (PDMS)) have been widely investigated for biomedical applications. The fidelity of the printing process in PDMS is assessed by optical coherence tomography, and the conducting polymer structures are demonstrated to be capable of stimulating mouse brain tissue in vitro. Furthermore, the applicability of the approach to printing structures in vivo is demonstrated in live nematodes (<jats:italic>Caenorhabditis elegans</jats:italic>). These results highlight the potential for such additive manufacturing approaches to produce next‐generation advanced material technologies, notably integrated electronics for technical and medical applications (e.g., human‐computer interfaces).</jats:p>

Item Type: Article
Uncontrolled Keywords: additive manufacturing, bioelectronics, conducting polymers, integrated electronics, neural electrodes
Divisions: Faculty of Science and Engineering > School of Electrical Engineering, Electronics and Computer Science
Depositing User: Symplectic Admin
Date Deposited: 17 Mar 2023 09:29
Last Modified: 25 Sep 2023 07:01
DOI: 10.1002/admt.202201274
Open Access URL: https://doi.org/10.1002/admt.202201274
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3169136
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