Vasikasin, Vasin, Rawson, Timothy M 
ORCID: 0000-0002-2630-9722, Holmes, Alison H ORCID: 0000-0001-5554-5743 and Otter, Jonathan
(2023)
Can precision antibiotic prescribing help prevent the spread of carbapenem-resistant organisms in the hospital setting?
JAC-ANTIMICROBIAL RESISTANCE, 5 (2).
dlad036-.
ISSN 2632-1823, 2632-1823
Abstract
The emergence of carbapenem-resistant organisms (CROs) is a significant global threat. Reduction of carbapenem consumption can decrease CROs. In the global endemic era of ESBL-producing bacteria, carbapenems are considered the treatment of choice, leading to challenge in limiting carbapenem use. This review describes the role of precision prescribing for prevention of CROs. This involves improving antibiotic selection, dosing and shortening duration. The effect of different antibiotics, dosing and duration on CRO development are explored. Available options for precision prescribing, gaps in the scientific evidence, and areas for future research are also presented.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 3207 Medical Microbiology, 32 Biomedical and Clinical Sciences, Prevention, Antimicrobial Resistance, Infectious Diseases, Infection |
| Divisions: | Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Systems, Molec & Integrative Biology > Inst. Systems, Molec & Integrative Biology |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 29 Sep 2023 09:10 |
| Last Modified: | 16 Jan 2026 10:35 |
| DOI: | 10.1093/jacamr/dlad036 |
| Open Access URL: | https://doi.org/10.1093/jacamr/dlad036 |
| Related Websites: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3173188 |
| Disclaimer: | The University of Liverpool is not responsible for content contained on other websites from links within repository metadata. Please contact us if you notice anything that appears incorrect or inappropriate. |
Altmetric
Altmetric