Diagnosis of equine pituitary pars intermedia dysfunction.

Stewart, Allison J, Ireland, Joanne L ORCID: 0000-0002-5737-1502, Durham, Andy E and McGowan, Catherine M ORCID: 0000-0002-1946-9584
(2023) Diagnosis of equine pituitary pars intermedia dysfunction. Veterinary journal (London, England : 1997), 300-30. p. 106036.

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Equine pituitary pars intermedia dysfunction (PPID) is common in aged horses. The majority of horses respond well to treatment, but treatment is lifelong, meaning accurate diagnosis of PPID is important. Similar to any condition, there is no perfect laboratory test to diagnose PPID and accuracy is affected by the characteristics of the population in which the test is being evaluated. This review details the importance of consideration of clinical factors and diagnostic test accuracy. Basal adrenocorticotrophic hormone (ACTH) concentration is used most frequently in practice and has very good diagnostic accuracy when used in combination with clinical judgement and the correct application of diagnostic thresholds. The thyrotropin-releasing hormone stimulation test can be used in horses with equivocal test results following basal ACTH testing, or to evaluate subtle cases due to its improved accuracy.

Item Type: Article
Uncontrolled Keywords: Animals, Horses, Pituitary Diseases, Horse Diseases, Thyrotropin-Releasing Hormone, Adrenocorticotropic Hormone, Pituitary Gland, Intermediate
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User: Symplectic Admin
Date Deposited: 16 Oct 2023 08:32
Last Modified: 08 Dec 2023 12:34
DOI: 10.1016/j.tvjl.2023.106036
Open Access URL: https://doi.org/10.1016/j.tvjl.2023.106036
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3173722