Molecular antimicrobial susceptibility testing in sepsis.

Martin-Loeches, Ignacio, Pereira, João Gonçalves, Teoh, Tee Keat, Barlow, Gavin, Dortet, Laurent, Carrol, Enitan D ORCID: 0000-0001-8357-7726, Olgemöller, Ulrike, Boyd, Sara E ORCID: 0000-0001-9935-5263 and Textoris, Julien (2024) Molecular antimicrobial susceptibility testing in sepsis. Future microbiology, 19 (1). pp. 61-72. ISSN 1746-0913, 1746-0921

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Abstract

Rapidly detecting and identifying pathogens is crucial for appropriate antimicrobial therapy in patients with sepsis. Conventional diagnostic methods have been a great asset to medicine, though they are time consuming and labor intensive. This work will enable healthcare professionals to understand the bacterial community better and enhance their diagnostic capacity by using novel molecular methods that make obtaining quicker, more precise results possible. The authors discuss and critically assess the merits and drawbacks of molecular testing and the added value of these tests, including the shift turnaround time, the implication for clinicians' decisions, gaps in knowledge, future research directions and novel insights or innovations. The field of antimicrobial molecular testing has seen several novel insights and innovations to improve the diagnosis and management of infectious diseases.

Item Type:	Article
Uncontrolled Keywords:	antibiotics, AST, bacteremia, ICU, MDR, microbiology, molecular testing, pneumonia, sepsis, septic shock
Divisions:	Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences
Depositing User:	Symplectic Admin
Date Deposited:	23 Jan 2024 08:31
Last Modified:	28 Feb 2026 20:49
DOI:	10.2217/fmb-2023-0128
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3177935
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