Prevalence of swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19: the PHOSP-COVID analysis

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Dawson, Camilla, Clunie, Gemma, Evison, Felicity, Duncan, Sallyanne, Whitney, Julie, Houchen-Wolloff, Linzy, Bolton, Charlotte E, Leavy, Olivia C, Richardson, Matthew, Omer, Elneima et al (show 39 more authors) , McAuley, Hamish, Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Saunders, Ruth M, Harris, Victoria C, Greening, Neil J, Nolan, Claire Marie, Wootton, Dan Gower ORCID: 0000-0002-5903-3881, Daynes, Enya, Donaldson, Gavin, Sargent, Jack, Scott, Janet, Pimm, John, Bishop, Lettie, McNarry, Melitta, Hart, Nicholas, Evans, Rachael A, Singh, Sally, Yates, Tom, Chalder, Trudie, Man, William, Harrison, Ewen, Docherty, Annemarie, Lone, Nazir I, Quint, Jennifer K, Chalmers, James, Ho, Ling-Pei, Horsley, Alex Robert, Marks, Michael, Poinasamy, Krisnah, Raman, Betty, Wain, Louise V, Brightling, Chris, PHOSP-COVID Collaborative Grp, Neil, Sharma, Neil, Coffey, Margaret, Kulkarni, Amit and Wallace, Sarah (2023) Prevalence of swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19: the PHOSP-COVID analysis BMJ OPEN RESPIRATORY RESEARCH, 10 (1). e001647-. ISSN 2052-4439, 2052-4439

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Abstract

Objective Identify prevalence of self-reported swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19. Design Multicentre prospective observational cohort study using questionnaire data at visit 1 (2-7 months post discharge) and visit 2 (10-14 months post discharge) from hospitalised patients in the UK. Lasso logistic regression analysis was undertaken to identify associations. Setting 64 UK acute hospital Trusts. Participants Adults aged >18 years, discharged from an admissions unit or ward at a UK hospital with COVID-19. Main outcome measures Self-reported swallow, communication, voice and cognitive compromise. Results Compromised swallowing post intensive care unit (post-ICU) admission was reported in 20% (188/955); 60% with swallow problems received invasive mechanical ventilation and were more likely to have undergone proning (p=0.039). Voice problems were reported in 34% (319/946) post-ICU admission who were more likely to have received invasive (p<0.001) or non-invasive ventilation (p=0.001) and to have been proned (p<0.001). Communication compromise was reported in 23% (527/2275) univariable analysis identified associations with younger age (p<0.001), female sex (p<0.001), social deprivation (p<0.001) and being a healthcare worker (p=0.010). Cognitive issues were reported by 70% (1598/2275), consistent at both visits, at visit 1 respondents were more likely to have higher baseline comorbidities and at visit 2 were associated with greater social deprivation (p<0.001). Conclusion Swallow, communication, voice and cognitive problems were prevalent post hospitalisation for COVID-19, alongside whole system compromise including reduced mobility and overall health scores. Research and testing of rehabilitation interventions are required at pace to explore these issues.

Item Type:	Article
Uncontrolled Keywords:	ARDS, COVID-19, critical care, pneumonia
Divisions:	Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences
Depositing User:	Symplectic Admin
Date Deposited:	02 Feb 2024 10:30
Last Modified:	24 Jan 2026 04:30
DOI:	10.1136/bmjresp-2023-001647
Open Access URL:	https://bmjopenrespres.bmj.com/content/10/1/e00164...
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3178298
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