Postpartum haemorrhage: latest developments in prediction, drug treatment and monitoring

Phan, Thuan ORCID: 0000-0002-7166-8345 and Weeks, Andrew D ORCID: 0000-0002-1909-337X (2024) Postpartum haemorrhage: latest developments in prediction, drug treatment and monitoring. British Journal of Midwifery, 32 (4). pp. 190-201. ISSN 0969-4900, 2052-4307

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Abstract

<jats:p> With increasing global rates of postpartum haemorrhage, recent developments aim to ensure that birthing women are safe. This focused review will discuss developments in prediction of postpartum haemorrhage, blood loss measurement, uterotonic use and the thromboelastogram, aiming to improve prevention and treatment of postpartum haemorrhage. The unpredictable nature of postpartum haemorrhage is a significant hurdle, as all women must be considered at risk, imposing a heavy burden on healthcare services. Evidence-based tools have shown promise in improving prediction and management strategies. However, the lack of consensus and agreement on risk factors presents obstacles to developing accurate models. Ongoing research is exploring the development of an individual postpartum haemorrhage risk index, providing personalised care to pregnant women. Accurate blood loss quantification is essential for prompt postpartum haemorrhage diagnosis and appropriate interventions, but challenging in busy clinical settings. Recent advancements in prophylaxis and treatment using medication (uterotonics and tranexamic acid), as well as in monitoring using thromboelastograms, emphasise the need for effective prediction and management strategies. This critical review underscores the need for further research to enhance prediction tools, refine management protocols and address existing challenges to improve maternal outcomes. </jats:p>

Item Type:	Article
Uncontrolled Keywords:	4206 Public Health, 42 Health Sciences, Maternal Health, Women's Health, Prevention, Maternal Morbidity and Mortality, Reproductive health and childbirth, 3 Good Health and Well Being
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	04 Apr 2024 13:04
Last Modified:	19 Aug 2025 13:44
DOI:	10.12968/bjom.2024.32.4.190
Related Websites:	Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3180074