Trichinopoly Krishna, Sandhya 
ORCID: 0000-0002-4535-8896, Millward, Christopher, Mallucci, Conor, Gamble, Carrol ORCID: 0000-0002-3021-1955, Jenkinson, Michael ORCID: 0000-0003-4587-2139 and Pizer, Barry
(2022)
SURG-13. The COMBAT Project - Core post operative morbidity set for paediatric brain tumours
Neuro-Oncology, 24 (Supple).
i144-i145.
ISSN 1522-8517, 1523-5866
Abstract
Abstract BACKGROUND: Brain tumours are associated with high morbidity both from the tumour and the medical and surgical interventions used to treat them. Post operative morbidity reporting following surgery for paediatric brain tumours is poor due to the lack of a common language when reporting harms. One solution is to develop a core adverse outcome set to stipulate the minimum post operative harms that should be reported. The COMBAT (Core post operative morbidity set for paediatric brain tumours) Project will develop a core adverse outcome set that can be applied to post operative paediatric brain tumour patients to harmonise how harms are measured and reported, enabling comparison between different trials, studies and clinical services. We aim to generate interest in the COMBAT Project and invite collaboration with healthcare professionals and researchers experienced in paediatric neuro oncology surgery. METHODS AND ANALYSIS : A systematic review will identify harms reported in post operative paediatric brain tumour patients and how they are measured. We will engage with national and international stakeholders including healthcare professionals, researchers, patients and their carers. Qualitative interviews with patients and carers will identify any important harms not extracted in the systematic review. A Delphi survey will be created from the harms identified. An international consensus meeting will be held to finalise the core adverse outcomes set. The final core adverse outcome set will be published and disseminated to encourage uptake. DISCUSSION: There is a clear need for a common language to harmonise measurement and reporting of harms following surgery for paediatric brain tumour patients. The core adverse outcome set will be developed with collaboration with key stakeholder groups to ensure it is representative. It will be used to standardise surgical morbidity outcome measurement and reporting in trials, studies and clinical practice and will inform future research in this field.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 32 Biomedical and Clinical Sciences, 3202 Clinical Sciences, Patient Safety, Clinical Research, Neurosciences, 7.1 Individual care needs, Cancer |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 16 Jul 2024 09:13 |
| Last Modified: | 15 Jan 2026 19:57 |
| DOI: | 10.1093/neuonc/noac079.531 |
| Open Access URL: | https://doi.org/10.1093/neuonc/noac079.531 |
| Related Websites: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3182904 |
| Disclaimer: | The University of Liverpool is not responsible for content contained on other websites from links within repository metadata. Please contact us if you notice anything that appears incorrect or inappropriate. |
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