Davis, William, Crosland, Andrew and Dukes‐McEwan, Joanna
(2024)
Canine dilated cardiomyopathy. Part 1: screening, diagnosis and management of preclinical DCM.
In Practice, 46 (9).
pp. 473-484.
ISSN 0263-841X, 2042-7689
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ELEMENTS Canine dilated cardiomyopathy Screening diagnosis and management of preclinical DCM-Accepted.pdf - Author Accepted Manuscript Available under License Creative Commons Attribution. Download (2MB) | Preview |
Abstract
<jats:p><jats:bold>Background</jats:bold>: Canine dilated cardiomyopathy (DCM) is a disease of the myocardium classically characterised by progressive eccentric hypertrophy (dilation) and systolic dysfunction of typically the left ventricle; however, DCM can also manifest as electrical abnormalities resulting in arrhythmic forms of the disease. The aetiology is idiopathic and there is often a genetic basis, which explains its over‐representation in certain breeds. Preclinical DCM describes the usually protracted period where an individual dog experiences structural changes over several years, or an arrhythmia (in specific breeds) that meet criteria for diagnosis without outward clinical signs of disease. Detection of this phase is crucial to facilitate early intervention with medical treatment, close monitoring and prognostication. Clinical DCM describes progression to congestive heart failure; the management of this will be discussed in the second part of this series, to be published in a subsequent issue of <jats:italic>In Practice</jats:italic>.</jats:p><jats:p><jats:bold>Aim of the article</jats:bold>: This article discusses case selection for DCM screening, including the utility of cardiac biomarkers. It outlines the echocardiographic diagnostic criteria for preclinical DCM, as well as the identification of arrhythmias that may be primary in nature or associated with the presence of cardiac remodelling. The medical management of preclinical DCM and associated arrhythmias is also discussed.</jats:p>
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 3009 Veterinary Sciences, 30 Agricultural, Veterinary and Food Sciences, Heart Disease, Rare Diseases, Clinical Research, Cardiovascular, Prevention, 4.1 Discovery and preclinical testing of markers and technologies, 4.2 Evaluation of markers and technologies, Cardiovascular |
| Divisions: | Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 26 Nov 2024 16:10 |
| Last Modified: | 26 Oct 2025 21:40 |
| DOI: | 10.1002/inpr.486 |
| Related Websites: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3188893 |
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