Development of ROBUST-RCT: Risk of Bias instrument for Use in SysTematic reviews-for Randomised Controlled Trials


Wang, Y ORCID: 0000-0002-2296-1991, Keitz, S, Briel, M, Glasziou, P, Brignardello-Petersen, R, Siemieniuk, RAC, Zeraatkar, D, Akl, EA, Armijo-Olivo, S, Bassler, D et al (show 8 more authors) (2025) Development of ROBUST-RCT: Risk of Bias instrument for Use in SysTematic reviews-for Randomised Controlled Trials BMJ, 388. e081199-. ISSN 0959-8146, 1756-1833

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Abstract

Recent innovations in evidence based medicine methods, in particular instruments assessing risk of bias in randomised trials, have focused on methodological rigour at the expense of simplicity and practicability. Such a focus could lead to challenges in application and loss of reliability of instruments. To deal with these shortcomings, the Risk Of Bias instrument for Use in SysTematic reviews-for Randomised Controlled Trials (ROBUST-RCT) was created—a rigorously developed, simply structured, and user friendly instrument for assessing risk of bias of randomised controlled trials included in systematic reviews. This paper describes the development of ROBUST-RCT and provides associated documents and a manual of instructions.

Item Type: Article
Uncontrolled Keywords: 4202 Epidemiology, 42 Health Sciences, Clinical Trials and Supportive Activities, Clinical Research, 8.4 Research design and methodologies (health services), Generic health relevance
Divisions: Faculty of Health & Life Sciences
Faculty of Health & Life Sciences > Inst. Population Health
Depositing User: Symplectic Admin
Date Deposited: 02 Apr 2025 08:14
Last Modified: 28 Feb 2026 00:48
DOI: 10.1136/bmj-2024-081199
Related Websites:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3191138
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