An in silico comparison of a novel CORA-based cranial closing wedge ostectomy methodology with three other techniques

Petchell, William HR ORCID: 0000-0003-4840-5616, Bostock, Anna R, German, Alexander J ORCID: 0000-0002-3017-7988 and Tomlinson, Andrew W (2025) An in silico comparison of a novel CORA-based cranial closing wedge ostectomy methodology with three other techniques VETERINARY SURGERY, 54 (7). pp. 1353-1365. ISSN 0161-3499, 1532-950X

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Abstract

Objective: To describe a CORA-based cranial closing wedge ostectomy methodology (CCWO<inf>CORA</inf>) and to determine whether the CCWO<inf>CORA</inf> achieves a more accurate and precise postoperative tibial plateau angle (TPA<inf>POST</inf>) than three previously described methods. Study design: In silico study. Sample population: Thirteen client-owned dogs. Methods: Computed tomography (CT) scans of six Labrador retriever, six German shepherd, six Rottweiler, and six small-breed dog (<10 kg) tibiae, originally acquired for unrelated purposes, were used for in silico planning and execution of the CCWO<inf>CORA</inf> and previously described procedures. The TPA<inf>POST</inf>, tibial long axis shift, change in tibial length and wedge angle were recorded and a linear mixed-effects model was used to compare differences amongst techniques. Results: The median TPA<inf>POST</inf> for the CCWO<inf>CORA</inf> method was 5.00° (range: 5.00–5.00°) across a variety of tibial morphologies, whereas all other methods showed greater variability. Differences in TPA<inf>POST</inf> were evident amongst methods (p <.001) and breeds (p <.001). Conclusions: In silico, CCWO<inf>CORA</inf> methodology always achieved the target TPA<inf>POST</inf> due to its intrinsic geometric principles. As such, CCWO<inf>CORA</inf> surgeries achieved a more accurate TPA<inf>POST</inf> than previously described CCWO techniques. Clinical significance: The CCWO<inf>CORA</inf> provides clinicians with a cranial closing-wedge ostectomy methodology with entirely predictable TPA<inf>POST</inf>.

Item Type:	Article
Uncontrolled Keywords:	Tibia, Skull, Animals, Dogs, Tomography, X-Ray Computed, Osteotomy, Computer Simulation, Female, Male
Divisions:	Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Life Courses & Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	11 Jun 2025 08:27
Last Modified:	23 May 2026 10:18
DOI:	10.1111/vsu.14277
Open Access URL:	https://doi.org/10.1111/vsu.14277
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3193180
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