van de Weyer, Yannick, Bexton, Steve, Ricci, Emanuele 
ORCID: 0000-0001-9751-0661, Chantrey, Julian ORCID: 0000-0002-4801-7034, Tilston, Valerie, Dervas, Eva, Seehusen, Frauke, Gomez-Vitores, Ana, Nabb, Liz, Kitchen, Hannah et al (show 3 more authors)
(2026)
Lymphoma in European hedgehogs (Erinaceus europaeus): A case series
VETERINARY PATHOLOGY, 63 (2).
pp. 212-217.
ISSN 0300-9858, 1544-2217
Abstract
Neoplasia is rarely reported in European hedgehogs (Erinaceus europaeus). A retrospective search was conducted by contacting multiple veterinary diagnostic laboratories for cases of lymphoma in European hedgehogs. This resulted in 5 cases, from which clinical, gross, histologic, and immunophenotyping findings were recorded. Most animals (3/5) had skin masses involving the cervical region, 1 hedgehog had dyspnea and lethargy associated with hydrothorax, whereas another exhibited icterus and lethargy. The primary site of the lymphoma was the skin, particularly the neck or head (3/5), the thymus (1/5), and multicentric (1/5). Immunophenotyping confirmed B-cell lymphoma in 2 skin cases, a T-cell lineage for the thymic and multicentric cases, and undetermined for the remaining skin lymphoma. CD3, PAX5, and CD79a were reliable immunohistochemistry markers in formalin-fixed tissues in European hedgehogs. Although uncommon, lymphoma should be considered in the differential diagnosis for adult European hedgehogs with skin nodules, especially those seeming to originate from the neck.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CD3, lymphoma, European hedgehog, hydrothorax, neoplasia, skin nodule, thymus |
| Divisions: | Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 05 Sep 2025 09:23 |
| Last Modified: | 23 May 2026 10:31 |
| DOI: | 10.1177/03009858251367380 |
| Open Access URL: | https://journals.sagepub.com/doi/10.1177/030098582... |
| Related Websites: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3194298 |
| Disclaimer: | The University of Liverpool is not responsible for content contained on other websites from links within repository metadata. Please contact us if you notice anything that appears incorrect or inappropriate. |
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