Effect of Probiotics in Breast Cancer: A Systematic Review and Meta-Analysis (vol 12, 280, 2023)



Thu, May S, Ondee, Thunnicha, Nopsopon, Tanawin, Farzana, Izzati AK, Fothergill, Joanne L ORCID: 0000-0002-7012-1508, Hirankarn, Nattiya, Campbell, Barry J ORCID: 0000-0002-7407-012X and Pongpirul, Krit
(2025) Effect of Probiotics in Breast Cancer: A Systematic Review and Meta-Analysis (vol 12, 280, 2023) BIOLOGY-BASEL, 14 (8). 991-. ISSN 2079-7737, 2079-7737

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Abstract

There was an error in the original publication [1]. Data was incorrectly extracted from Table 3 of Juan et al. [53], where we had taken the value for % body fat in the post-probiotic group and compared it to body weight in the post-placebo group. Data has been reanalyzed using the correct value for % body fat in the post-placebo group. A correction has been made to Section 3.8. Three studies assessed percentage change in body fat (BF%) after probiotics intervention. Use of probiotics reduced BF% in both breast cancer patients and survivors (MD = −1.81; 95% CI: −5.22 to 1.61; p = 0.30; Figure 4A). Subgroup analysis demonstrated that ProLBE supplements significantly reduced the elevation of BF% in breast cancer patients (MD = −4.20; 95% CI: −7.59 to −0.81; p = 0.02) while a smaller decrease in BF% occurred in breast cancer survivors with use of ProLBS capsules (Figure 4B). As such, a correction has also been made to Table 4 and Figure 4 to reflect the revised analysis. The corrected Table 4 appears below: Quantitative subgroup analysis for all the included trials. Abbreviations: BMI, body mass index; BF%, percentage change in body fat; FOS, fructo-oligosaccharides; N/A, not available. The corrected Figure 4 appears below: Meta-analysis for (A) percentage change in body fat (BF%) percent and (B) BF% by probiotic type. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Item Type: Article
Uncontrolled Keywords: 31 Biological Sciences, Women's Health, Cancer, Breast Cancer, Complementary and Integrative Health, Nutrition, Cancer, 3 Good Health and Well Being
Divisions: Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences > Inst. Infection, Vet & Ecological Sciences (T&R Staff)
Faculty of Health & Life Sciences
Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences
Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences > Clinical Infection, Microbiology & Immunology
Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences > Infection Biology & Microbiomes
Depositing User: Symplectic Admin
Date Deposited: 24 Mar 2026 08:20
Last Modified: 11 Oct 2026 09:49
DOI: 10.3390/biology14080991
Open Access URL: https://doi.org/10.3390/biology14080991
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URI: https://livrepository.liverpool.ac.uk/id/eprint/3197670
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