Evans, Ceri 
ORCID: 0000-0001-9122-9748, Chandna, Jaya, Mutasa, Kuda, Rukobo, Sandra, Govha, Margaret, Mushayanembwa, Patience, Chasekwa, Bernard, Majo, Florence D, Kandawasvika, Gwendoline, Mutasa, Batsirai et al (show 5 more authors)
(2026)
Neurodevelopment in Children Exposed to Antenatal CMV Viremia in a High HIV Prevalence Area
JOURNAL OF INFECTIOUS DISEASES.
jiag214-.
ISSN 0022-1899, 1537-6613
Abstract
We compared neurodevelopment at age 24-months among children born to mothers with or without CMV viraemia in the third trimester of pregnancy in rural Zimbabwe, using the Malawi Developmental Assessment Tool (MDAT) for gross motor, fine motor, language and social development. Among 209 children, 49 (23%) were exposed to third trimester CMV viraemia. The mean total MDAT score was 91.0 (SD 9.4) in CMV-exposed children versus 94.1 (8.8) in CMV-unexposed children (adjusted difference -4.02 points (95% confidence interval -7.01, -1.04, P=0.008). CMV exposure in utero, without evidence of congenital infection, may impair child neurodevelopment, providing a potential antenatal intervention target.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Africa, HIV-exposed uninfected, co-infection, CMV, pregnancy |
| Divisions: | Faculty of Health & Life Sciences Faculty of Health & Life Sciences > Inst. Life Courses & Medical Sciences Faculty of Health & Life Sciences > Inst. Life Courses & Medical Sciences > Inst. Life Courses & Medical Sciences (T&R staff) Faculty of Health & Life Sciences > Inst. Life Courses & Medical Sciences > Women's & Children's Health Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences > Inst. Infection, Vet & Ecological Sciences (T&R Staff) Faculty of Health & Life Sciences > Inst. Infection, Vet & Ecological Sciences > Clinical Infection, Microbiology & Immunology |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 20 Apr 2026 13:17 |
| Last Modified: | 23 May 2026 11:14 |
| DOI: | 10.1093/infdis/jiag214 |
| Open Access URL: | https://academic.oup.com/jid/advance-article/doi/1... |
| Related Websites: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3198061 |
| Disclaimer: | The University of Liverpool is not responsible for content contained on other websites from links within repository metadata. Please contact us if you notice anything that appears incorrect or inappropriate. |
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