Williamson, Paula R ORCID: 0000-0001-9802-6636 and Gamble, Carrol
ORCID: 0000-0002-3021-1955
(2007)
Application and investigation of a bound for outcome reporting bias.
Trials, 8 (1).
9-.
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Abstract
<h4>Background</h4>Direct empirical evidence for the existence of outcome reporting bias is accumulating and this source of bias is recognised as a potential threat to the validity of meta-analysis of randomised clinical trials.<h4>Methods</h4>A method for calculating the maximum bias in a meta-analysis due to publication bias is adapted for the setting where within-study selective non-reporting of outcomes is suspected, and compared to the alternative approach of missing data imputation. The properties of both methods are investigated in realistic small sample situations.<h4>Results</h4>The results suggest that the adapted Copas and Jackson approach is the preferred method for reviewers to apply as an initial assessment of robustness to within-study selective non-reporting.<h4>Conclusion</h4>The Copas and Jackson approach is a useful method for systematic reviewers to apply to assess robustness to outcome reporting bias.
Item Type: | Article |
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Additional Information: | Published: 6 March 2007. Issue: 12 pages (page numbers not for citation purposes). |
Uncontrolled Keywords: | PUBLICATION BIAS, RANDOMIZED-TRIALS, SELECTION BIAS, METAANALYSIS |
Subjects: | ?? R1 ?? |
Divisions: | Faculty of Health and Life Sciences |
Depositing User: | Symplectic Admin |
Date Deposited: | 27 Jun 2008 13:21 |
Last Modified: | 17 Dec 2022 00:25 |
DOI: | 10.1186/1745-6215-8-9 |
Publisher's Statement : | © 2007 Williamson and Gamble; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/721 |