Experimental infection of laboratory-bred bank voles (<i>Myodes glareolus</i>) with murid herpesvirus 4

Hughes, David J, Kipar, Anja ORCID: 0000-0001-7289-3459, Leeming, Gail ORCID: 0000-0003-3409-399X, Sample, Jeffery T and Stewart, James P ORCID: 0000-0002-8928-2037 (2012) Experimental infection of laboratory-bred bank voles (<i>Myodes glareolus</i>) with murid herpesvirus 4. ARCHIVES OF VIROLOGY, 157 (11). pp. 2207-2212.

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Abstract

MuHV-4 is a natural pathogen of rodents of the genus Apodemus (e.g., wood mice, yellow-necked mice) and Myodes glareolus (bank voles). We report experimental MuHV-4 infection of bank voles in comparison with infection of A. sylvaticus (wood mice) and BALB/c mice. Like in wood mice, the level of productive replication in the lungs of bank voles was significantly lower than in BALB/c mice. In contrast to other hosts, however, the level of latent infection in the lung and spleen of bank voles was extremely low. These findings, together with those of previous studies, suggest that bank voles are an occasional and inefficient host for MuHV-4.

Item Type:	Article
Additional Information:	## TULIP Type: Articles/Papers (Journal) ##
Uncontrolled Keywords:	Animal Structures, Animals, Mice, Inbred BALB C, Mice, Rhadinovirus, Herpesviridae Infections, Tumor Virus Infections, Rodent Diseases, Models, Theoretical, Arvicolinae, Murinae
Depositing User:	Symplectic Admin
Date Deposited:	23 Mar 2015 12:11
Last Modified:	12 Oct 2023 19:57
DOI:	10.1007/s00705-012-1397-5
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/2007321