Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry



Nieves, Daniel, Azmi, Nina, Xu, Ruoyan, Levy, Raphael ORCID: 0000-0001-5728-0531, Yates, Ed ORCID: 0000-0001-9365-5433 and Fernig, David ORCID: 0000-0003-4875-4293
(2014) Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry. Chemical Communications, 50 (86). pp. 13157-13160.

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Abstract

A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.

Item Type: Article
Uncontrolled Keywords: Copper, Gold, Maleimides, Sulfhydryl Compounds, Oligosaccharides, Fibroblast Growth Factor 2, Metal Nanoparticles, Click Chemistry
Depositing User: Symplectic Admin
Date Deposited: 18 Jun 2015 14:23
Last Modified: 02 May 2023 00:56
DOI: 10.1039/c4cc05909c
Publisher's Statement : This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/2013823