Clinical and laboratory features of HIV/AIDS in the Kingdom of Saudi Arabia

Bajhmoum, Wail Clinical and laboratory features of HIV/AIDS in the Kingdom of Saudi Arabia. PhD thesis, University of Liverpool.

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Abstract

There are insufficient data on the epidemiology and clinical features of HIV in the Middle East. WHO statistics show the Kingdom of Saudi Arabia (KSA) to be one of the least affected countries globally. However, the Saudi National Program for HIV Control reported a 34.6% increase in cases in 2008 from the previous year. Jeddah region has the highest proportion of HIV cases in KSA (40%). Infection risk data are not always complete and coinfection rates have not been studied. The first part of these studies included a retrospective longitudinal case review of all patients attending the Jeddah clinic to obtain a clearer view of clinical and epidemiological features of that population There are few publications about resistance to antiretroviral therapy (ART) in the Arabian Peninsula, including KSA, and most are heavily biased towards assessment of patients with sequential treatment failure. Wider access to resistance testing has only become available recently and baseline local resistance patterns are largely unknown. The aim of the second part of the study was to determine patterns of ART resistance in a systematic fashion in treatment-naïve HIV positive Saudi patients and to document the presence and frequency of novel resistance HIV markers in Jeddah. Study Part 1. Clinical features and epidemiology of HIV and coinfection with TB and/or viral hepatitis in a large clinic in Jeddah, Kingdom of Saudi Arabia Aims: To describe demographic and clinical features of HIV infection in clinics and hospitals in Jeddah and to document prevalence and risks for coinfections with tuberculosis (TB) and/or hepatitis Methods: Retrospective study including all HIV positive Saudi adults attending the main treatment centre in Jeddah in the 11 years (2000-2010). Data were systematically collected from case files and summarised. Statistical comparisons included univariate analyses with a p value

Item Type:	Thesis (PhD)
Additional Information:	Date: 2015-06-09 (completed)
Depositing User:	Symplectic Admin
Date Deposited:	30 Jul 2015 11:11
Last Modified:	17 Dec 2022 01:31
DOI:	10.17638/02014239
URI:	https://livrepository.liverpool.ac.uk/id/eprint/2014239