Surgery for epilepsy: a systematic review of current evidence



West, Siobhan, Nolan, Sarah J ORCID: 0000-0001-9988-2709 and Newton, Richard
(2016) Surgery for epilepsy: a systematic review of current evidence. EPILEPTIC DISORDERS, 18 (2). pp. 113-121.

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Abstract

This seminar discusses the history and development of techniques for surgical intervention for people with refractory focal epilepsy. Published surgical success rates and prognostic factors associated with post-operative seizure freedom from individual studies have been variable and contradictory. We present here the key findings of a Cochrane systematic review of all evidence published since the introduction of magnetic resonance imaging (MRI) to pre-operative surgical assessment in 1984. Our findings show the usefulness of uncontrolled case series is now past. Future studies with a prospective controlled design should focus on specific research questions to help improve results and provide better-informed advice.

Item Type: Article
Uncontrolled Keywords: focal epilepsy, surgical resection, systematic review
Depositing User: Symplectic Admin
Date Deposited: 08 Dec 2016 11:11
Last Modified: 02 Oct 2023 13:46
DOI: 10.1684/epd.2016.0825
Open Access URL: http://www.jle.com/fr/revues/epd/e-docs/surgery_fo...
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URI: https://livrepository.liverpool.ac.uk/id/eprint/3004010