de Magalhaes, Joao Pedro ORCID: 0000-0002-6363-2465, Stevens, Michael and Thornton, Daniel ORCID: 0000-0002-4994-2942
(2017)
The Business of Anti-Aging Science.
TRENDS IN BIOTECHNOLOGY, 35 (11).
pp. 1062-1073.
Text
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Abstract
Age-related conditions are the leading causes of death and health-care costs. Reducing the rate of aging would have enormous medical and financial benefits. Myriad genes and pathways are known to regulate aging in model organisms, fostering a new crop of anti-aging companies. Approaches range from drug discovery efforts to big-data methods and direct-to-consumer (DTC) strategies. Challenges and pitfalls of commercialization include reliance on findings from short-lived model organisms, poor biological understanding of aging, and hurdles in performing clinical trials for aging. A large number of potential aging-associated interventions and targets exist, but given the long validation times only a small fraction can be explored for clinical applications. If even one company succeeds, however, the impact will be huge.
Item Type: | Article |
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Uncontrolled Keywords: | Animals, Humans, Biotechnology, Aging, Biomedical Research |
Depositing User: | Symplectic Admin |
Date Deposited: | 14 Aug 2017 06:44 |
Last Modified: | 19 Jan 2023 06:58 |
DOI: | 10.1016/j.tibtech.2017.07.004 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3008938 |