Universal statistics of epithelial tissue topology

Abdullah, Abdulaziz, Avraam, Demetris, Chepizhko, Oleksandr, Vaccari, Thomas, Zapperi, Stefano, Porta, Caterina AM La and Vasiev, Bakhtier ORCID: 0000-0002-3452-7885
(2017) Universal statistics of epithelial tissue topology. Arxiv.

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Cells forming various epithelial tissues have a strikingly universal distribution for the number of their edges. It is generally assumed that this topological feature is predefined by the statistics of individual cell divisions in growing tissue but existing theoretical models are unable to predict the observed distribution. Here we show experimentally, as well as in simulations, that the probability of cellular division increases exponentially with the number of edges of the dividing cell and show analytically that this is responsible for the observed shape of cell-edge distribution.

Item Type: Article
Additional Information: 3 figures
Uncontrolled Keywords: q-bio.TO, q-bio.TO, physics.bio-ph
Depositing User: Symplectic Admin
Date Deposited: 03 Jul 2020 08:48
Last Modified: 18 Jan 2023 23:48
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3091820