Jjunju, Fred PM ORCID: 0000-0001-6257-434X, Damon, Deidre E, Romero-Perez, David, Young, Iain S ORCID: 0000-0002-9502-6216, Ward, Ryan J ORCID: 0000-0002-9850-5191, Marshall, Alan ORCID: 0000-0002-8058-5242, Maher, Simon and Badu-Tawiah, Abraham K
(2020)
Analysis of non-conjugated steroids in water using paper spray mass spectrometry.
Scientific Reports, 10 (1).
10698-.
Abstract
A novel strategy for the direct analysis of non-conjugated steroids in water using paper spray mass spectrometry (PS-MS) has been developed. PS-MS was used in the identification and quantification of non-conjugated (free) steroids in fish tank water samples. Data shown herein indicates that individual amounts of free steroids can be detected in aqua as low as; 0.17 ng/µL, 0.039 ng/µL, 0.43 ng/µL, 0.0076 ng/µL for aldosterone, corticosterone, cortisol, and β-estrone, respectively, and with an average relative standard deviation of ca. < 10% in the positive ion mode using PS-MS/MS. Direct detection of free steroids in a raw water mixture, from aquaculture, without prior sample preparation is demonstrated. The presence of free steroids released in fish water samples was confirmed via tandem mass spectrometry using collision-induced dissociation. This approach shows promise for rapid and direct water quality monitoring to provide a holistic assessment of non-conjugated steroids in aqua.
Item Type: | Article |
---|---|
Depositing User: | Symplectic Admin |
Date Deposited: | 06 Jul 2020 09:28 |
Last Modified: | 18 Jan 2023 23:47 |
DOI: | 10.1038/s41598-020-67484-7 |
Open Access URL: | https://www.nature.com/articles/s41598-020-67484-7 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3092667 |