Disulfide Promoted C−P Bond Cleavage of Phosphoramide: “P” Surrogates to Synthesize Phosphonates and Phosphinates

Hou, Fei, Du, Xing‐Peng, Alduma, Anwar I, Li, Zhi‐Feng, Huo, Cong‐De, Wang, Xi‐Cun, Wu, Xiao‐Feng ORCID: 0000-0001-5549-8836 and Quan, Zheng‐Jun (2020) Disulfide Promoted C−P Bond Cleavage of Phosphoramide: “P” Surrogates to Synthesize Phosphonates and Phosphinates. Advanced Synthesis & Catalysis, 362 (21). pp. 4755-4760.

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Official URL: http://dx.doi.org/10.1002/adsc.202000511

Abstract

<jats:title>Abstract</jats:title><jats:p>A metal‐free C−P bond cleavage reaction is described herein. Phosphoramides, a phosphine source, can react with alcohols to produce phosphonate and phosphinate derivatives in the presence of a disulfide. P−H<jats:sub>2</jats:sub>, P‐alkyl, and P,P‐dialkyl phosphoramides can be used as substrates to obtain the corresponding pentavalent phosphine products.</jats:p><jats:p><jats:boxed-text content-type="graphic" position="anchor"><jats:graphic xmlns:xlink="http://www.w3.org/1999/xlink" mimetype="image/png" position="anchor" specific-use="enlarged-web-image" xlink:href="graphic/adsc202000511-toc-0001-m.png"><jats:alt-text>magnified image</jats:alt-text></jats:graphic></jats:boxed-text> </jats:p>

Item Type:	Article
Uncontrolled Keywords:	C-P bond cleavage, Disulfide, Alkyl phosphonates, Phosphoramides, Phosphinates
Depositing User:	Symplectic Admin
Date Deposited:	03 Dec 2020 08:08
Last Modified:	18 Sep 2023 19:05
DOI:	10.1002/adsc.202000511
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3108884