Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection



Hobson, James Joseph ORCID: 0000-0003-2551-1774, Savage, Alison Clare ORCID: 0000-0002-5312-9946, Dwyer, Andrew, Unsworth, Catherine, Massam, Jonathan, Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee M ORCID: 0000-0001-9448-8876, Rajoli, Rajith ORCID: 0000-0002-6015-5712
et al (show 9 more authors) (2021) Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection. Nanoscale, 13 (13). pp. 6410-6416.

Access the full-text of this item by clicking on the Open Access link.

Abstract

<p>The control of COVID-19 across the world requires the formation of a range of interventions including vaccines to elicit an immune response and immunomodulatory or antiviral therapeutics. Here, we demonstrate...</p>

Item Type: Article
Uncontrolled Keywords: Humans, Niclosamide, Antiviral Agents, Injections, Intramuscular, Nanoparticles, SARS-CoV-2, COVID-19 Drug Treatment
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Faculty of Science and Engineering > School of Physical Sciences
Depositing User: Symplectic Admin
Date Deposited: 23 Jun 2021 10:37
Last Modified: 11 Feb 2023 03:00
DOI: 10.1039/d1nr00309g
Open Access URL: https://pubs.rsc.org/en/content/articlelanding/202...
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3127423