The quest of vision: retina’s daily challenges



Dhirachaikulpanich, Dhanach ORCID: 0000-0003-2234-1837, Paraoan, Robert AI, Carlsson, Emil and Paraoan, Luminita ORCID: 0000-0001-7568-7116
(2020) The quest of vision: retina’s daily challenges. The Biochemist, 42 (5). pp. 4-10.

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Abstract

<jats:p>The retina is a complex biological structure located at the back of the eye. Every day, it continually performs an intricate set of tasks to provide us with the sense of vision. The neuroretina encompasses neuronal type of cells including the light-sensitive photoreceptors, which sense the incoming light and trigger the conversion of the visual stimulus information to a neural response relayed to our brain where images are created. This article focuses on the physiological processes occurring in the retina and the exquisite interplay between photoreceptors and the adjacent cell monolayer called the retinal pigment epithelium, which underpins the key visual processes of phototransduction, visual cycle and phagocytosis of spent photoreceptors’ outer segments. We also present examples of functional defects in the retina and how they lead to impaired vision or blindness, and discuss some emerging treatment options for retinal diseases.</jats:p>

Item Type: Article
Uncontrolled Keywords: Clinical Research, Eye Disease and Disorders of Vision, Neurosciences, Eye
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 02 Jul 2021 08:23
Last Modified: 15 Mar 2024 05:04
DOI: 10.1042/bio20200061
Open Access URL: https://doi.org/10.1042/BIO20200061
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3128528