Outcomes of microvascular composite reconstruction for mandibular osteoradionecrosis

O'Connell, JE, Brown, JS, Rogers, SN, Bekiroglu, F, Schache, A ORCID: 0000-0001-9466-6038 and Shaw, RJ ORCID: 0000-0002-5157-4042
(2021) Outcomes of microvascular composite reconstruction for mandibular osteoradionecrosis. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 59 (9). pp. 1031-1035.

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The aim of this retrospective study was to compare outcomes and reconstruction-related complications in patients receiving a composite free flap reconstruction of the mandible for ORN with those reconstructed for other indications. The records of all patients who underwent composite reconstruction of a mandibular defect at Aintree University Hospital, Liverpool, were reviewed and analysed. Based on radiotherapy exposure and ORN history, the study cohort was divided into three separate case-matched groups. Local wound healing issues were markedly more common in the ORN setting, as was infection and subsequent osteosynthesis plate(s) removal. Free flap survival was similar among all three case-matched groups. Advanced mandibular ORN may be safely and predictably reconstructed with composite free flaps, and that while the rate of local complications is greater than non-irradiated, and non-ORN case-matched controls, the free flap survival rate compares favourably.

Item Type: Article
Uncontrolled Keywords: osteoradionecrosis, composite free flap, mandible
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User: Symplectic Admin
Date Deposited: 04 Oct 2021 14:37
Last Modified: 18 Jan 2023 21:27
DOI: 10.1016/j.bjoms.2020.11.013
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3139248