Juvenile Idiopathic Arthritis Associated Uveitis



Carlsson, Emil, Beresford, Michael W, Ramanan, Athimalaipet V, Dick, Andrew D and Hedrich, Christian M ORCID: 0000-0002-1295-6179
(2021) Juvenile Idiopathic Arthritis Associated Uveitis. CHILDREN-BASEL, 8 (8). 646-.

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Abstract

Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease. The development of associated uveitis represents a significant risk for serious complications, including permanent loss of vision. Initiation of early treatment is important for controlling JIA-uveitis, but the disease can appear asymptomatically, making frequent screening procedures necessary for patients at risk. As our understanding of pathogenic drivers is currently incomplete, it is difficult to assess which JIA patients are at risk of developing uveitis. Identification of specific risk factors for JIA-associated uveitis is an important field of research, and in this review, we highlight the genomic, transcriptomic, and proteomic factors identified as potential uveitis risk factors in JIA, and discuss therapeutic strategies.

Item Type: Article
Uncontrolled Keywords: juvenile idiopathic arthritis, uveitis, biomarkers, risk factors
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 03 Nov 2021 16:57
Last Modified: 18 Jan 2023 21:25
DOI: 10.3390/children8080646
Open Access URL: https://doi.org/10.1186/s12969-016-0088-2
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3142664