Challenges in cardiovascular pharmacogenomics implementation: a viewpoint from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy


Magavern, Emma F, Kaski, Juan Carlos, Turner, Richard M, Drexel, Heinz, Janmohamed, Azara, Scourfield, Andrew, Burrage, Daniel, Floyd, Christopher N, Adeyeye, Elizabeth, Tamargo, Juan et al (show 11 more authors) (2022) Challenges in cardiovascular pharmacogenomics implementation: a viewpoint from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy. EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY, 8 (1). pp. 100-103.

[img] Text
ESC PGx Viewpoint EHJ January 27 (003).docx - Author Accepted Manuscript
Download (47kB)

Abstract

Pharmacogenomics promises to advance cardiovascular therapy, but there remain pragmatic barriers to implementation. These are particularly important to explore within Europe, as there are differences in the populations, availability of resources, and expertise, as well as in ethico-legal frameworks. Differences in healthcare delivery across Europe present a challenge, but also opportunities to collaborate on pharmacogenomics implementation. Clinical workforce upskilling is already in progress but will require substantial input. Digital infrastructure and clinical support tools are likely to prove crucial. It is important that widespread implementation serves to narrow rather than widen any existing gaps in health equality between populations. This viewpoint supplements the working group position paper on cardiovascular pharmacogenomics to address these important themes.

Item Type: Article
Uncontrolled Keywords: Pharmacogenomics, Therapeutics, Pharmacotherapy, Genetics
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User: Symplectic Admin
Date Deposited: 13 Apr 2022 13:41
Last Modified: 18 Jan 2023 21:05
DOI: 10.1093/ehjcvp/pvab063
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3152879
Dimensions
Altmetric
CORE (COnnecting REpositories)