Addition of Lymphatic Stimulating Self-Care Practices Reduces Acute Attacks among People Affected by Moderate and Severe Lower-Limb Lymphedema in Ethiopia, a Cluster Randomized Controlled Trial



Douglass, Jan, Hailekiros, Fikre, Martindale, Sarah, Mableson, Hayley, Seife, Fikre, Bishaw, Tesfahun, Nigussie, Mekdes, Meribo, Kadu, Tamiru, Mossie, Agidew, Getnet
et al (show 4 more authors) (2020) Addition of Lymphatic Stimulating Self-Care Practices Reduces Acute Attacks among People Affected by Moderate and Severe Lower-Limb Lymphedema in Ethiopia, a Cluster Randomized Controlled Trial. JOURNAL OF CLINICAL MEDICINE, 9 (12). E4077-.

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Abstract

Lymphedema causes disability and exacerbates poverty in many countries. The management of lymphatic filariasis (LF) and podoconiosis-related lymphedema involves daily hygiene to reduce secondary infections, but self-massage and deep-breathing, which have proven beneficial in cancer-related lymphedema, are not included. A cluster randomized trial in northern Ethiopia investigated the effects of lymphatic stimulation for people affected by moderate to severe lymphedema. Participants were allocated to either standard (control <i>n</i> = 59) or enhanced (intervention <i>n</i> = 67) self-care groups. Primary outcomes were lymphedema stage, mid-calf circumference, and tissue compressibility. Secondary outcomes were the frequency and duration of acute attacks. After 24 weeks, fewer patients were assessed as severe (control -37.8%, intervention -42.4%, <i>p</i> = 0.15) and there were clinically relevant changes in mid-calf tissue compressibility but not circumference. There was a significant between-group difference in patients who reported any acute attacks over the study period (control <i>n</i> = 22 (38%), intervention <i>n</i> = 7 (12%), <i>p</i> = 0.014). Daily lymphedema self-care resulted in meaningful benefits for all participants with a greater reduction in acute episodes among people performing lymphatic stimulation. Observations of a change in lymphedema status support earlier findings in Bangladesh and extend the demonstrated benefits of enhanced self-care to people affected by podoconiosis.

Item Type: Article
Uncontrolled Keywords: lymphedema, lower limb, filariasis, podoconiosis, self-care, breathing, exercise, skin mobilisation, lymphatic massage
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User: Symplectic Admin
Date Deposited: 09 Jun 2022 13:52
Last Modified: 03 Feb 2024 09:35
DOI: 10.3390/jcm9124077
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3156119