Hossack, Martin, Simpson, Gregory, Shaw, Penelope, Fisher, Robert, Torella, Francesco 
ORCID: 0000-0003-0529-7387, Brennan, John and Smout, Jonathan
(2022)
Open Retroperitoneal Repair for Complex Abdominal Aortic Aneurysms.
Aorta (Stamford, Conn.), 10 (3).
pp. 114-121.
Abstract
<h4>Background</h4> Open surgical repair (OSR) of complex abdominal aortic aneurysms (CAAAs) can be challenging. We frequently utilize the retroperitoneal (RP) approach for such cases. We audited our outcomes with the aim of establishing the utility and safety of this approach.<h4>Methods</h4> Retrospective analysis was performed of all patients undergoing OSR of an unruptured CAAA via a RP approach in our center over a 7-year period. Data on repairs via a transperitoneal (TP) approach were collected to provide context. Demographic, operative, radiological, and biochemical data were collected. The primary outcome measure was 30-day/inpatient mortality. Secondary outcomes included the need for reoperation, incidence of postoperative chest infection, acute kidney injury (AKI) and length of stay (LOS). All patients received aortic clamping above at least one main renal artery.<h4>Results</h4> One hundred and three patients underwent OSR of an unruptured CAAA; 55 via a RP approach, 48 TP. The RP group demonstrated a more advanced pattern of disease with a larger median maximum diameter (65 vs. 61 mm, <i>p</i>= 0.013) and a more proximal extent. Consequently, the rate of supravisceral clamping was higher in RP repair (66 vs. 15%, <i>p</i> < 0.001). Despite this there were no differences in the observed early mortality (9.1 vs. 10%, NS); incidence of reoperation (10.9 vs. 12.5%, NS), chest infection (32.7 vs. 25%, NS), and AKI (52.7 vs. 45.8%, NS); or median LOS (10 vs. 12 days, NS) following RP and TP repair.<h4>Conclusion</h4> OSR of CAAAs carries significant 30-day mortality. In patients unsuitable for fenestrated endovascular aortic repair or those desiring a durable long-term solution, OSR can be performed through the RP or TP approach. This study has demonstrated that in our unit RP repair facilitates treatment of more advanced AAA utilizing complex proximal clamp zones with similar perioperative morbidity and mortality compared with TP cases utilizing more distal clamping.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Rare Diseases, Patient Safety, Kidney Disease, Clinical Research, Cardiovascular, 3 Good Health and Well Being |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 11 Nov 2022 11:31 |
| Last Modified: | 15 Mar 2024 11:53 |
| DOI: | 10.1055/s-0042-1748959 |
| Open Access URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC96260... |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3166161 |
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