Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher et al (show 1 more authors)
(2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes.
BRITISH JOURNAL OF PHARMACOLOGY, 174 (Suppl ).
S272-S359.
Abstract
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13877/full. Enzymes are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CGTP Collaborators, Animals, Humans, Enzymes, Ligands, Knowledge Bases, Databases, Pharmaceutical |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 15 Dec 2022 15:03 |
| Last Modified: | 17 Dec 2022 05:11 |
| DOI: | 10.1111/bph.13877 |
| Open Access URL: | https://bpspubs.onlinelibrary.wiley.com/doi/10.111... |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3166697 |
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