Abuelgasim, Eyad, Shah, Suleyman, Abuelgasim, Biyaser, Soni, Nikita, Thomas, Ashvin, Elgasim, Mustafa and Harky, Amer ORCID: 0000-0001-5507-5841
(2021)
Clinical overview of diabetes mellitus as a risk factor for cardiovascular death.
REVIEWS IN CARDIOVASCULAR MEDICINE, 22 (2).
pp. 301-314.
Abstract
Global diabetes mellitus prevalence is increasing. Metabolic disorders, such as type 2 diabetes, are associated with abnormal cardiac electrophysiology and increased risk of arrhythmias. Patients with both diabetes types (1 and 2) suffer from sudden cardac death (SCD) as a leading cause of mortality. Cardiovascular death is defined as death attributable to cardiovascular disease (CVD) occurring shortly within the symptom onset. This usually arises from life-threatening ventricular tachyarrhythmias that lead to hemodynamic instability, and subsequent shock and death. A variety of pathways have been suggested that link hypoglycaemia to the development of adverse cardiovascular outcomes, including blood coagulation abnormalities, inflammation, endothelial dysfunction and sympathoadrenal responses. We propose a four-step framework for the optimisation of SCD risk factors in diabetic patients, to include: raising awareness to influence health behaviour, provision of screening programs, use of technology within educational programs to improve patient engagement and effective provision of diabetic community teams.
Item Type: | Article |
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Uncontrolled Keywords: | Diabetes mellitus, Cardiovascular disease, Sudden cardiac death, Hypoglycaemia, Cardiomyopathy |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology |
Depositing User: | Symplectic Admin |
Date Deposited: | 02 Feb 2023 15:47 |
Last Modified: | 02 Feb 2023 15:47 |
DOI: | 10.31083/j.rcm2202038 |
Open Access URL: | https://doi.org/10.31083/j.rcm2202038 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3168108 |