The advantages of sub-sampling and Inpainting for scanning transmission electron microscopy



Browning, Nigel D ORCID: 0000-0003-0491-251X, Castagna, Jony, Kirkland, Angus I, Moshtaghpour, Amirafshar ORCID: 0000-0002-6751-2698, Nicholls, Daniel ORCID: 0000-0003-1677-701X, Robinson, Alex W ORCID: 0000-0002-1901-2509, Wells, Jack and Zheng, Yalin ORCID: 0000-0002-7873-0922
(2023) The advantages of sub-sampling and Inpainting for scanning transmission electron microscopy. APPLIED PHYSICS LETTERS, 122 (5). 050501-050501.

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Abstract

<jats:p>Images and spectra obtained from aberration corrected scanning transmission electron microscopes (STEM) are now used routinely to quantify the morphology, structure, composition, chemistry, bonding, and optical/electronic properties of nanostructures, interfaces, and defects in many materials/biological systems. However, obtaining quantitative and reproducible atomic resolution observations from some experiments is actually harder with these ground-breaking instrumental capabilities, as the increase in beam current from using the correctors brings with it the potential for electron beam modification of the specimen during image acquisition. This beam effect is even more acute for in situ STEM observations, where the desired outcome being investigated is a result of a series of complicated transients, all of which can be modified in unknown ways by the electron beam. The aim in developing and applying new methods in STEM is, therefore, to focus on more efficient use of the dose that is supplied to the sample and to extract the most information from each image (or set of images). For STEM (and for that matter, all electron/ion/photon scanning systems), one way to achieve this is by sub-sampling the image and using Inpainting algorithms to reconstruct it. By separating final image quality from overall dose in this way and manipulating the dose distribution to be best for the stability of the sample, images can be acquired both faster and with less beam effects. In this paper, the methodology behind sub-sampling and Inpainting is described, and the potential for Inpainting to be applied to novel real time dynamic experiments will be discussed.</jats:p>

Item Type: Article
Uncontrolled Keywords: Regenerative Medicine, Stem Cell Research
Divisions: Faculty of Health and Life Sciences
Faculty of Science and Engineering > School of Engineering
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 06 Feb 2023 16:13
Last Modified: 15 Mar 2024 10:26
DOI: 10.1063/5.0135245
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3168215