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Abrams, Simon T, Su, Dunhao, Sahraoui, Yasmina, Lin, Ziqi, Cheng, Zhenxing, Nesbitt, Kate, Alhamdi, Yasir, Harrasser, Micaela, Du, Min, Foley, Jonathan H et al (show 3 more authors)
(2021)
Assembly of alternative prothrombinase by extracellular histones initiates and disseminates intravascular coagulation.
BLOOD, 137 (1).
pp. 103-114.
Shaw, Rebecca J 
ORCID: 0000-0002-1190-7244, Bradbury, Charlotte, Abrams, Simon T, Wang, Guozheng ORCID: 0000-0001-5525-3548 and Toh, Cheng-Hock
(2021)
COVID-19 and immunothrombosis: emerging understanding and clinical management.
BRITISH JOURNAL OF HAEMATOLOGY, 194 (3).
pp. 518-529.
Cheng, Zhenxing, Abrams, Simon T, Austin, James, Toh, Julien, Wang, Susan Siyu, Wang, Zhi, Yu, Qian, Yu, Weiping, Toh, Cheng Hock and Wang, Guozheng ORCID: 0000-0001-5525-3548
(2020)
The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development.
MEDIATORS OF INFLAMMATION, 2020.
7418342-.
Cheng, Zhenxing, Abrams, Simon T, Alhamdi, Yasir, Toh, Julien, Yu, Weiping, Wang, Guozheng ORCID: 0000-0001-5525-3548 and Toh, Cheng-Hock
(2019)
Circulating Histones Are Major Mediators of Multiple Organ Dysfunction Syndrome in Acute Critical Illnesses.
Critical care medicine, 47 (8).
e677-e684.
Abrams, Simon T, Zhang, Nan, Manson, Joanna, Liu, Tingting, Dart, Caroline ORCID: 0000-0002-3509-8349, Baluwa, Florence, Wang, Susan Siyu, Brohi, Karim, Kipar, Anja ORCID: 0000-0001-7289-3459, Yu, Weiping et al (show 2 more authors)
(2013)
Circulating Histones Are Mediators of Trauma-associated Lung Injury.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187 (2).
pp. 160-169.
Alhamdi, Yasir, Abrams, Simon T, Cheng, Zhenxing ORCID: 0000-0001-9595-4760, Jing, Shengjie, Su, Dunhao, Liu, Zhiyong, Lane, Steven, Welters, Ingeborg ORCID: 0000-0001-8734-994X, Wang, Guozheng ORCID: 0000-0001-5525-3548 and Toh,, Cheng-Hock
(2015)
Circulating histones are major mediators of cardiac injury in patients with sepsis.
Critical Care Medicine, 43 (10).
pp. 2094-2103.
Shaw, Rebecca J ORCID: 0000-0002-1190-7244, Abrams, Simon T, Austin, James, Taylor, Joseph M, Lane, Steven, Dutt, Tina, Downey, Colin, Du, Min, Turtle, Lance ORCID: 0000-0002-0778-1693, Baillie, J Kenneth et al (show 4 more authors)
(2021)
Circulating histones play a central role in COVID-19-associated coagulopathy and mortality.
HAEMATOLOGICA, 106 (9).
pp. 2493-2498.
Cheng, Zhenxing, Abrams, Simon T, Toh, Julien, Wang, Susan S, Downey, Colin, Ge, Xiaoling, Yu, Qian, Yu, Weiping, Wang, Guozheng ORCID: 0000-0001-5525-3548 and Toh, Cheng-Hock
(2020)
Complexes between C-Reactive Protein and Very Low Density Lipoprotein Delay Bacterial Clearance in Sepsis.
Journal of Immunology, 204 (10).
pp. 2712-2721.
Cheng, Zhenxing, Abrams, Simon T, Toh, Julien, Wang, Susan Siyu, Wang, Zhi, Yu, Qian, Yu, Weiping, Toh, Cheng-Hock and Wang, Guozheng ORCID: 0000-0001-5525-3548
(2020)
The Critical Roles and Mechanisms of Immune Cell Death in Sepsis.
FRONTIERS IN IMMUNOLOGY, 11.
1918-.
Toh, Cheng-Hock, Alhamdi, Yasir and Abrams, Simon T
(2016)
Current Pathological and Laboratory Considerations in the Diagnosis of Disseminated Intravascular Coagulation.
ANNALS OF LABORATORY MEDICINE, 36 (6).
pp. 505-512.
Qaddoori, Yasir, Abrams, Simon T, Mould, Paul, Alhamdi, Yasir, Christmas, Stephen E, Wang, Guozheng ORCID: 0000-0001-5525-3548 and Toh, Cheng-Hock
(2018)
Extracellular Histones Inhibit Complement Activation through Interacting with Complement Component 4.
JOURNAL OF IMMUNOLOGY, 200 (12).
pp. 4125-4133.
Wang, Zhi, Cheng, Zhen-Xing, Abrams, Simon T, Lin, Zi-Qi, Yates, ED, Yu, Qian, Yu, Wei-Ping, Chen, Ping-Sheng, Toh, Cheng-Hock and Wang, Guo-Zheng ORCID: 0000-0001-5525-3548
(2020)
Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway.
WORLD JOURNAL OF GASTROENTEROLOGY, 26 (47).
pp. 7513-7527.
Schoergenhofer, Christian, Schwameis, Michael, Wohlfarth, Philipp, Brostjan, Christine, Abrams, Simon T, Toh, Cheng-Hock and Jilma, Bernd
(2017)
Granulocyte colony-stimulating factor (G-CSF) increases histone-complexed DNA plasma levels in healthy volunteers.
CLINICAL AND EXPERIMENTAL MEDICINE, 17 (2).
pp. 243-249.
Abrams, Simon T, Morton, Ben ORCID: 0000-0002-6164-2854, Alhamdi, Yasir, Alsabani, Mohmad, Lane, Steven, Welters, Ingeborg D ORCID: 0000-0001-8734-994X, Wang, Guozheng ORCID: 0000-0001-5525-3548 and Toh, Cheng-Hock
(2019)
A Novel Assay for Neutrophil Extracellular Trap Formation Independently Predicts Disseminated Intravascular Coagulation and Mortality in Critically Ill Patients.
American journal of respiratory and critical care medicine, 200 (07).
pp. 869-880.
Moxon, Christopher A, Alhamdi, Yasir, Storm, Janet, Toh, Julien MH, McGuinness, Dagmara, Ko, Joo Yeon, Murphy, George, Lane, Steven, Taylor, Terrie E, Seydel, Karl B et al (show 10 more authors)
(2020)
Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria.
Blood Advances, 4 (13).
pp. 2851-2864.
Alsabani, Mohmad, Abrams, Simon T, Cheng, Zhenxing, Morton, Ben, Lane, Steven, Alosaimi, Samar, Yu, Weiping, Wang, Guozheng ORCID: 0000-0001-5525-3548 and Toh, Cheng-Hock
(2022)
Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsis.
British Journal of Anaesthesia, 128 (2).
pp. 283-293.
Szatmary, Peter ORCID: 0000-0002-7454-9851, Liu, Tingting, Abrams, Simon T, Voronina, Svetlana, Wen, Li, Chvanov, Michael, Huang, Wei, Wang, Guozheng ORCID: 0000-0001-5525-3548, Criddle, David N ORCID: 0000-0003-2952-8450, Tepikin, Alexey V et al (show 2 more authors)
(2017)
Systemic histone release disrupts plasmalemma and contributes to necrosis in acute pancreatitis.
PANCREATOLOGY, 17 (6).
pp. 884-892.