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Gonzalez-Galarza, Faviel F, McCabe, Antony ORCID: 0000-0003-3089-3674, Santos, Eduardo J Melo dos, Jones, James, Takeshita, Louise
ORCID: 0000-0003-4288-4388, Ortega-Rivera, Nestor D, Cid-Pavon, Glenda M Del, Ramsbottom, Kerry
ORCID: 0000-0002-7432-9293, Ghattaoraya, Gurpreet, Alfirevic, Ana
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Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools.
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Navaratnam, Kate, Alfirevic, Ana ORCID: 0000-0002-2801-9817, Jorgensen, Andrea
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ORCID: 0000-0001-9276-518X
(2018)
Aspirin non-responsiveness in pregnant women at high-risk of pre-eclampsia.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 221.
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Ball, Amy L, Bloch, Katarzyna M, Rainbow, Lucille ORCID: 0000-0003-0447-6885, Liu, Xuan, Kenny, John, Lyon, Jonathan J, Gregory, Richard, Alfirevic, Ana
ORCID: 0000-0002-2801-9817 and Chadwick, Amy E
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(2021)
Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers.
Archives of Toxicology, 95 (4).
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Monangi, Nagendra, Xu, Huan, Khanam, Rasheda, Khan, Waqasuddin, Deb, Saikat, Pervin, Jesmin, Price, Joan T, Kennedy, Stephen H, Al Mahmud, Abdullah, Fan, Yuemei et al (show 54 more authors)
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Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis.
BMJ GLOBAL HEALTH, 6 (9).
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Siddiqui, Moneeza Kalhan, Veluchamy, Abirami, Maroteau, Cyrielle, Tavendale, Roger, Carr, Fiona, Pearson, Ewan, Colhoun, Helen, Morris, Andrew D, George, Jacob, Doney, Alexander et al (show 7 more authors)
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CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia.
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Ogese, Monday O ORCID: 0000-0002-1873-4032, Lister, Adam, Jenkins, Rosalind E, Meng, Xiaoli
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ORCID: 0000-0001-8384-824X, Pirmohamed, Munir
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Characterization of Clozapine-Responsive Human T Cells.
JOURNAL OF IMMUNOLOGY, 205 (9).
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Jaruthamsophon, Kanoot, Thomson, Paul J ORCID: 0000-0001-5431-0459, Hammond, Sean, Zhang, Eunice, Alfirevic, Ana
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Characterization of Drug-Specific CD4+T-Cells Reveals Possible Roles of HLA Class II in the Pathogenesis of Carbamazepine Hypersensitivity Reactions.
CHEMICAL RESEARCH IN TOXICOLOGY, 36 (5).
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Goldstein, Jacqueline I, Jarskog, L Fredrik, Hilliard, Chris, Alfirevic, Ana ORCID: 0000-0002-2801-9817, Duncan, Laramie, Fourches, Denis, Huang, Hailiang, Lek, Monkol, Neale, Benjamin M, Ripke, Stephan et al (show 21 more authors)
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Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
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Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout.
Rheumatology (Oxford, England), 56 (10).
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Ogese, Monday O ORCID: 0000-0002-1873-4032, Lister, Adam, Gardner, Joshua, Meng, Xiaoli
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Deciphering Adverse Drug Reactions: In Vitro Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01.
TOXICOLOGICAL SCIENCES, 183 (1).
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Faulkner, Lee, Gibson, Andrew, Sullivan, Andrew, Tailor, Arun ORCID: 0000-0002-9698-3480, Usui, Toru, Alfirevic, Ana
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Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
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Bin Dayel, Faten F ORCID: 0009-0006-8181-8374, Alfirevic, Ana
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Developing In Vitro Models to Define the Role of Direct Mitochondrial Toxicity in Frequently Reported Drug-Induced Rhabdomyolysis.
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Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response.
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Examining the uptake of predictive BRCA testing in the UK; findings and implications.
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Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema.
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Generation and Validation of Transmitochondrial Cybrid and Platelet Models to Investigate the Effect of Mitochondrial Genotype upon Drug-Induced Liver Injury.
PhD thesis, University of Liverpool.
Lacaze, Paul, Ronaldson, Kathlyn J, Zhang, Eunice J ORCID: 0000-0003-1813-2207, Alfirevic, Ana
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Genetic testing for prevention of severe drug-induced skin rash.
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Genome and transcriptome profiling of spontaneous preterm birth phenotypes.
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Alfirevic, Ana ORCID: 0000-0002-2801-9817 and Pirmohamed, Munir
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HLA-A 31:01 is not associated with the development of methotrexate pneumonitis in the UK population: results from a genome-wide association study.
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Alfirevic, Ana ORCID: 0000-0002-2801-9817, Downing, Jennifer
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Has the introduction of direct oral anticoagulants (DOACs) in England increased emergency admissions for bleeding conditions? A longitudinal ecological study.
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Navaratnam, Kate, Alfirevic, Zarko ORCID: 0000-0001-9276-518X, Pirmohamed, Munir
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How important is aspirin adherence when evaluating effectiveness of low-dose aspirin?
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 219.
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Jorgensen, Andrea L ORCID: 0000-0002-6977-9337, Prince, Clare, Fitzgerald, Gai, Hanson, Anita, Downing, Jennife
ORCID: 0000-0001-7691-1167, Reynolds, Julia, Zhang, J Eunice
ORCID: 0000-0003-1813-2207, Alfirevic, Ana
ORCID: 0000-0002-2801-9817 and Pirmohamed, Munir
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Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study.
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Implementing computational techniques to investigate immune-mediated adverse drug reactions.
PhD thesis, University of Liverpool.
Bin Dayel, Faten ORCID: 0009-0006-8181-8374
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Investigating Mitochondrial Dysfunction as a Mechanism of Drug-Induced Muscle Toxicity.
Doctor of Philosophy thesis, University of Liverpool.
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Investigating Mitochondrial Impairment as a Mechanism of Statin-Induced Muscle Toxicity.
Doctor of Philosophy thesis, University of Liverpool.
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Investigation of immunogenetic risk factors for carbamazepine-induced hypersensitivity reactions.
PhD thesis, University of Liverpool.
Gupta, Juhi ORCID: 0000-0002-8292-9846
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MULTI-OMIC BIOMARKER DISCOVERY FOR SPONTANEOUS PRETERM BIRTH PREVENTION APPLYING MACHINE LEARNING METHODS.
PhD thesis, University of Liverpool.
Care, Angharad G ORCID: 0000-0003-2131-0406, Gupta, Juhi K
ORCID: 0000-0002-8292-9846, Goodfellow, Laura
ORCID: 0000-0002-8111-5007, Zhang, Ge, Monangi, Nagendra, Belling, Elizabeth, Landero, Julio, Chappell, Joanne, Sharp, Andrew
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Maternal selenium levels and whole genome screen in recurrent spontaneous preterm birth population: a nested case control study.
European Journal of Obstetrics & Gynecology and Reproductive Biology, 265.
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Metabolic profiling of maternal serum of women a high-risk of spontaneous preterm birth using NMR and MGWAS approach.
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Patient ethnicity and the risk of immune-mediated adverse drug reactions.
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Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing.
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Plasma long-chain omega-3 fatty acid status and risk of recurrent early spontaneous preterm birth: a prospective observational study.
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Platelet response to aspirin in UK and Irish pregnancy cohorts: a genome-wide approach.
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Patel, Waseema, Rimmer, Lara, Smith, Martin, Moss, Lucie, Smith, Mark A, Snodgrass, H Ralph, Pirmohamed, Munir ORCID: 0000-0002-7534-7266, Alfirevic, Ana
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Probenecid Increases the Concentration of 7-Chlorokynurenic Acid Derived from the Prodrug 4-Chlorokynurenine within the Prefrontal Cortex.
MOLECULAR PHARMACEUTICS, 18 (1).
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Processes and barriers to implementation of point-of-care genotype-guided dosing of warfarin into UK outpatient anticoagulation clinics.
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The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review.
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Role of transporters and enzymes in metabolism and distribution of 4 chlorokynurenine and metabolites.
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Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions.
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Socioeconomic and health factors related to polypharmacy and medication management: analysis of a Household Health Survey in North West Coast England.
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Systematic review of preterm birth multi-omic biomarker studies.
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Trends in BRCA testing over time and socioeconomic deprivation.
European Journal of Human Genetics.
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Using “Omics” to Discover Predictive Biomarkers in Women at High Risk of Spontaneous Preterm Birth.
PhD thesis, University of Liverpool.
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Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study.
This is the MedRxiv preprint - journal not yet known.
Giebel, Clarissa ORCID: 0000-0002-0746-0566, McIntyre, Jason Cameron
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An assessment of the impact of pharmacogenomics on health disparities: a systematic literature review.
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A common missense variant of LILRB5 is associated with statin intolerance and myalgia.
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The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury.
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