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Scott, Robert A, Freitag, Daniel F, Li, Li, Chu, Audrey Y, Surendran, Praveen, Young, Robin, Grarup, Niels ORCID: 0000-0001-5526-1070, Stancakova, Alena, Chen, Yuning, Varga, Tibor V ORCID: 0000-0002-2383-699X et al (show 140 more authors) , Yaghootkar, Hanieh, Luan, Jian'an, Zhao, Jing Hua, Willems, Sara M, Wessel, Jennifer ORCID: 0000-0002-7031-0085, Wang, Shuai, Maruthur, Nisa, Michailidou, Kyriaki ORCID: 0000-0001-7065-1237, Pirie, Ailith, van der Lee, Sven J ORCID: 0000-0003-1606-8643, Gillson, Christopher, Al Olama, Ali Amin, Amouyel, Philippe ORCID: 0000-0001-9088-234X, Arriola, Larraitz, Arveiler, Dominique, Aviles-Olmos, Iciar ORCID: 0000-0002-1645-7406, Balkau, Beverley, Barricarte, Aurelio, Barroso, Ines ORCID: 0000-0001-5800-4520, Garcia, Sara Benlloch, Bis, Joshua C, Blankenberg, Stefan, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Borecki, Ingrid B, Bork-Jensen, Jette, Bowden, Sarah ORCID: 0000-0001-7506-1340, Caldas, Carlos ORCID: 0000-0003-3547-1489, Caslake, Muriel, Cupples, L Adrienne ORCID: 0000-0003-0273-7965, Cruchaga, Carlos, Czajkowski, Jacek, den Hoed, Marcel ORCID: 0000-0001-8081-428X, Dunn, Janet A ORCID: 0000-0001-7313-4446, Earl, Helena M ORCID: 0000-0003-1549-8094, Ehret, Georg B, Ferrannini, Ele, Ferrieres, Jean ORCID: 0000-0001-6144-1297, Foltynie, Thomas, Ford, Ian, Forouhi, Nita G ORCID: 0000-0002-5041-248X, Gianfagna, Francesco ORCID: 0000-0003-4615-0816, Gonzalez, Carlos, Grioni, Sara ORCID: 0000-0002-5891-8426, Hiller, Louise, Jansson, Jan-Hakan, Jorgensen, Marit E, Jukema, J Wouter, Kaaks, Rudolf, Kee, Frank, Kerrison, Nicola D, Key, Timothy J, Kontto, Jukka ORCID: 0000-0003-3899-9852, Kote-Jarai, Zsofia, Kraja, Aldi T, Kuulasmaa, Kari ORCID: 0000-0003-2165-1411, Kuusisto, Johanna, Linneberg, Allan ORCID: 0000-0002-0994-0184, Liu, Chunyu, Marenne, Galle ORCID: 0000-0002-4363-7170, Mohlke, Karen L, Morris, Andrew P, Muir, Kenneth, Mueller-Nurasyid, Martina, Munroe, Patricia B, Navarro, Carmen ORCID: 0000-0001-8896-7483, Nielsen, Sune F, Nilsson, Peter M, Nordestgaard, Borge G, Packard, Chris J, Palli, Domenico ORCID: 0000-0002-5558-2437, Panico, Salvatore, Peloso, Gina M, Perola, Markus, Peters, Annette ORCID: 0000-0001-6645-0985, Poole, Christopher J, Quiros, J Ramn, Rolandsson, Olov, Sacerdote, Carlotta ORCID: 0000-0002-8008-5096, Salomaa, Veikko, Sanchez, Mara-Jose, Sattar, Naveed, Sharp, Stephen J, Sims, Rebecca, Slimani, Nadia, Smith, Jennifer A ORCID: 0000-0002-3575-5468, Thompson, Deborah J, Trompet, Stella, Tumino, Rosario, van der A, Daphne L, van der Schouw, Yvonne T ORCID: 0000-0002-4605-435X, Virtamo, Jarmo, Walker, Mark, Walter, Klaudia, Abraham, Jean E, Amundadottir, Laufey T ORCID: 0000-0003-1859-8971, Aponte, Jennifer L, Butterworth, Adams ORCID: 0000-0002-6915-9015, Dupuis, Josee ORCID: 0000-0003-2871-3603, Easton, Douglas F, Eeles, Rosalind A, Erdmann, Jeanette ORCID: 0000-0002-4486-6231, Franks, Paul W ORCID: 0000-0002-0520-7604, Frayling, Timothy M, Hansen, Torben ORCID: 0000-0001-8748-3831, Howson, Joanna MM ORCID: 0000-0001-7618-0050, Jorgensen, Torben, Kooner, Jaspal, Laakso, Markku, Langenberg, Claudia, McCarthy, Mark I, Pankow, James S ORCID: 0000-0001-7076-483X, Pedersen, Oluf ORCID: 0000-0002-3321-3972, Riboli, Elio ORCID: 0000-0001-6795-6080, Rotter, Jerome I, Saleheen, Danish, Samani, Nilesh J, Schunkert, Heribert, Vollenweider, Peter, O'Rahilly, Stephen, Deloukas, Panos ORCID: 0000-0001-9251-070X, Danesh, John, Goodarzi, Mark O, Kathiresan, Sekar, Meigs, James B, Ehm, Margaret G, Wareham, Nicholas J, Waterworth, Dawn M, Consortium, CVD50, Consortium, GERAD-EC, Grp, Neurology Working, CHARGE, , Consortiu, Alzheimer's Dis Genetics, Consortium, Pancreatic Canc Cohort, European, Prospective Invest Into C, EPIC-InterAct, , Consortium, CHARGE, Consortium, CHD Exome and Consortium, CARDIOGRAM Exome (2016) A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. SCIENCE TRANSLATIONAL MEDICINE, 8 (341).