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Bastard, Paul, Gervais, Adrian ORCID: 0000-0002-1083-5787, Le Voyer, Tom, Rosain, Jérémie, Philippot, Quentin, Manry, Jérémy, Michailidis, Eleftherios ORCID: 0000-0002-9907-4346, Hoffmann, Hans-Heinrich, Eto, Shohei, Garcia-Prat, Marina ORCID: 0000-0001-5387-1908 et al (show 191 more authors) , Bizien, Lucy, Parra-Martínez, Alba, Yang, Rui, Haljasmägi, Liis, Migaud, Mélanie, Särekannu, Karita, Maslovskaja, Julia, de Prost, Nicolas, Tandjaoui-Lambiotte, Yacine, Luyt, Charles-Edouard, Amador-Borrero, Blanca, Gaudet, Alexandre, Poissy, Julien, Morel, Pascal ORCID: 0000-0002-8916-7717, Richard, Pascale, Cognasse, Fabrice, Troya, Jesus, Trouillet-Assant, Sophie, Belot, Alexandre ORCID: 0000-0003-4902-5332, Saker, Kahina, Garçon, Pierre, Rivière, Jacques G, Lagier, Jean-Christophe ORCID: 0000-0003-0771-8245, Gentile, Stéphanie, Rosen, Lindsey B, Shaw, Elana ORCID: 0000-0001-9265-8026, Morio, Tomohiro, Tanaka, Junko, Dalmau, David, Tharaux, Pierre-Louis ORCID: 0000-0002-6062-5905, Sene, Damien, Stepanian, Alain, Megarbane, Bruno ORCID: 0000-0002-2522-2764, Triantafyllia, Vasiliki, Fekkar, Arnaud, Heath, James R, Franco, José Luis, Anaya, Juan-Manuel, Solé-Violán, Jordi, Imberti, Luisa ORCID: 0000-0002-2075-8391, Biondi, Andrea ORCID: 0000-0002-6757-6173, Bonfanti, Paolo ORCID: 0000-0001-7289-8823, Castagnoli, Riccardo ORCID: 0000-0003-0029-9383, Delmonte, Ottavia M, Zhang, Yu, Snow, Andrew L, Holland, Steven M, Biggs, Catherine, Moncada-Vélez, Marcela, Arias, Andrés Augusto, Lorenzo, Lazaro, Boucherit, Soraya, Coulibaly, Boubacar, Anglicheau, Dany, Planas, Anna M, Haerynck, Filomeen, Duvlis, Sotirija, Nussbaum, Robert L, Ozcelik, Tayfun, Keles, Sevgi, Bousfiha, Ahmed A, El Bakkouri, Jalila, Ramirez-Santana, Carolina, Paul, Stéphane, Pan-Hammarström, Qiang, Hammarström, Lennart, Dupont, Annabelle, Kurolap, Alina ORCID: 0000-0002-7005-3621, Metz, Christine N, Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Ciceri, Fabio, Barreiros, Lucila A, Dominguez-Garrido, Elena, Vidigal, Mateus, Zatz, Mayana, van de Beek, Diederik, Sahanic, Sabina, Tancevski, Ivan, Stepanovskyy, Yurii, Boyarchuk, Oksana, Nukui, Yoko, Tsumura, Miyuki, Vidaur, Loreto, Tangye, Stuart G, Burrel, Sonia, Duffy, Darragh, Quintana-Murci, Lluis, Klocperk, Adam, Kann, Nelli Y, Shcherbina, Anna, Lau, Yu-Lung, Leung, Daniel, Coulongeat, Matthieu, Marlet, Julien, Koning, Rutger, Reyes, Luis Felipe, Chauvineau-Grenier, Angélique, Venet, Fabienne, Monneret, Guillaume, Nussenzweig, Michel C, Arrestier, Romain, Boudhabhay, Idris, Baris-Feldman, Hagit, Hagin, David, Wauters, Joost, Meyts, Isabelle, Dyer, Adam H ORCID: 0000-0003-1356-510X, Kennelly, Sean P, Bourke, Nollaig M, Halwani, Rabih, Sharif-Askari, Narjes Saheb, Dorgham, Karim, Sallette, Jérome, Sedkaoui, Souad Mehlal, AlKhater, Suzan, Rigo-Bonnin, Raúl, Morandeira, Francisco, Roussel, Lucie, Vinh, Donald C, Ostrowski, Sisse Rye, Condino-Neto, Antonio, Prando, Carolina, Bonradenko, Anastasiia, Spaan, András N, Gilardin, Laurent, Fellay, Jacques, Lyonnet, Stanislas, Bilguvar, Kaya, Lifton, Richard P, Mane, Shrikant, HGID Lab, , COVID Clinicians, , COVID-STORM Clinicians, , NIAID Immune Response to COVID Group, , NH-COVAIR Study Group, , Danish CHGE, , Danish Blood Donor Study, , St. James's Hospital, , SARS CoV2 Interest group, , French COVID Cohort Study Group, , Imagine COVID-Group, , Milieu Intérieur Consortium, , CoV-Contact Cohort, , Amsterdam UMC Covid-19, , Biobank Investigators, , COVID Human Genetic Effort, , CONSTANCES cohort, , 3C-Dijon Study, , Cerba Health-Care, , Etablissement du Sang study group, , Anderson, Mark S, Boisson, Bertrand ORCID: 0000-0001-5240-3555, Béziat, Vivien ORCID: 0000-0002-4020-824X, Zhang, Shen-Ying, Vandreakos, Evangelos, Hermine, Olivier, Pujol, Aurora, Peterson, Pärt, Mogensen, Trine H, Rowen, Lee, Mond, James, Debette, Stéphanie, de Lamballerie, Xavier, Duval, Xavier, Mentré, France, Zins, Marie, Soler-Palacin, Pere, Colobran, Roger, Gorochov, Guy ORCID: 0000-0003-2097-9677, Solanich, Xavier, Susen, Sophie, Martinez-Picado, Javier, Raoult, Didier ORCID: 0000-0002-0633-5974, Vasse, Marc, Gregersen, Peter K, Piemonti, Lorenzo, Rodríguez-Gallego, Carlos, Notarangelo, Luigi D, Su, Helen C, Kisand, Kai, Okada, Satoshi, Puel, Anne ORCID: 0000-0003-2603-0323, Jouanguy, Emmanuelle, Rice, Charles M, Tiberghien, Pierre ORCID: 0000-0002-9310-8322, Zhang, Qian, Cobat, Aurélie, Abel, Laurent and Casanova, Jean-Laurent (2021) Autoantibodies neutralizing type I IFNs are present in <b>~</b>4% of uninfected individuals over 70 years old and account for <b>~</b>20% of COVID-19 deaths. Science immunology, 6 (62). eabl4340-.

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Zhang, Qian ORCID: 0000-0002-9040-3289, Bastard, Paul ORCID: 0000-0002-5926-8437, Liu, Zhiyong ORCID: 0000-0001-6473-348X, Le Pen, Jérémie ORCID: 0000-0001-7025-9526, Moncada-Velez, Marcela ORCID: 0000-0002-3073-5345, Chen, Jie ORCID: 0000-0002-5354-4170, Ogishi, Masato ORCID: 0000-0003-2421-7389, Sabli, Ira KD ORCID: 0000-0002-0170-2990, Hodeib, Stephanie ORCID: 0000-0002-5978-6189, Korol, Cecilia ORCID: 0000-0002-0023-8823 et al (show 128 more authors) , Rosain, Jérémie ORCID: 0000-0002-2822-161X, Bilguvar, Kaya ORCID: 0000-0002-7313-7652, Ye, Junqiang ORCID: 0000-0002-4529-0713, Bolze, Alexandre ORCID: 0000-0001-7399-2766, Bigio, Benedetta ORCID: 0000-0001-7291-5638, Yang, Rui ORCID: 0000-0003-4427-2158, Arias, Andrés Augusto ORCID: 0000-0002-9478-8403, Zhou, Qinhua ORCID: 0000-0002-5112-3727, Zhang, Yu, Onodi, Fanny, Korniotis, Sarantis, Karpf, Léa, Philippot, Quentin, Chbihi, Marwa ORCID: 0000-0002-2771-851X, Bonnet-Madin, Lucie ORCID: 0000-0002-9848-3287, Dorgham, Karim ORCID: 0000-0001-9539-3203, Smith, Nikaïa ORCID: 0000-0002-0202-612X, Schneider, William M ORCID: 0000-0001-9407-6118, Razooky, Brandon S ORCID: 0000-0002-5263-1512, Hoffmann, Hans-Heinrich ORCID: 0000-0003-0554-0244, Michailidis, Eleftherios ORCID: 0000-0002-9907-4346, Moens, Leen, Han, Ji Eun ORCID: 0000-0003-1112-9320, Lorenzo, Lazaro ORCID: 0000-0001-6648-8684, Bizien, Lucy ORCID: 0000-0001-9163-9122, Meade, Philip ORCID: 0000-0002-6754-7209, Neehus, Anna-Lena ORCID: 0000-0002-8573-6820, Ugurbil, Aileen Camille ORCID: 0000-0002-9450-3092, Corneau, Aurélien ORCID: 0000-0003-1272-6872, Kerner, Gaspard ORCID: 0000-0003-0146-9428, Zhang, Peng ORCID: 0000-0002-6129-567X, Rapaport, Franck ORCID: 0000-0001-6553-2110, Seeleuthner, Yoann, Manry, Jeremy ORCID: 0000-0001-5998-2051, Masson, Cecile ORCID: 0000-0001-7870-7821, Schmitt, Yohann, Schlüter, Agatha ORCID: 0000-0001-6732-1528, Le Voyer, Tom ORCID: 0000-0002-0630-8626, Khan, Taushif ORCID: 0000-0002-7917-8965, Li, Juan, Fellay, Jacques ORCID: 0000-0002-8240-939X, Roussel, Lucie ORCID: 0000-0001-5355-702X, Shahrooei, Mohammad, Alosaimi, Mohammed F ORCID: 0000-0002-8025-3491, Mansouri, Davood, Al-Saud, Haya, Al-Mulla, Fahd ORCID: 0000-0001-5409-3829, Almourfi, Feras ORCID: 0000-0002-5166-4662, Al-Muhsen, Saleh Zaid, Alsohime, Fahad ORCID: 0000-0002-4979-3895, Al Turki, Saeed ORCID: 0000-0001-7017-336X, Hasanato, Rana ORCID: 0000-0002-4697-2222, van de Beek, Diederik ORCID: 0000-0002-4571-044X, Biondi, Andrea ORCID: 0000-0002-6757-6173, Bettini, Laura Rachele ORCID: 0000-0002-0280-1704, D'Angio', Mariella, Bonfanti, Paolo ORCID: 0000-0001-7289-8823, Imberti, Luisa ORCID: 0000-0002-2075-8391, Sottini, Alessandra, Paghera, Simone, Quiros-Roldan, Eugenia, Rossi, Camillo, Oler, Andrew J ORCID: 0000-0002-6310-0434, Tompkins, Miranda F ORCID: 0000-0003-2941-7515, Alba, Camille ORCID: 0000-0002-0458-1629, Vandernoot, Isabelle, Goffard, Jean-Christophe, Smits, Guillaume ORCID: 0000-0003-2845-6758, Migeotte, Isabelle, Haerynck, Filomeen ORCID: 0000-0001-9161-7361, Soler-Palacin, Pere ORCID: 0000-0002-0346-5570, Martin-Nalda, Andrea ORCID: 0000-0002-3590-0186, Colobran, Roger ORCID: 0000-0002-5964-536X, Morange, Pierre-Emmanuel ORCID: 0000-0002-9065-722X, Keles, Sevgi, Çölkesen, Fatma ORCID: 0000-0001-9545-5179, Ozcelik, Tayfun, Yasar, Kadriye Kart ORCID: 0000-0003-2963-4894, Senoglu, Sevtap ORCID: 0000-0003-4796-9583, Karabela, Şemsi Nur ORCID: 0000-0003-2562-3004, Rodríguez-Gallego, Carlos ORCID: 0000-0002-4344-8644, Novelli, Giuseppe ORCID: 0000-0002-7781-602X, Hraiech, Sami, Tandjaoui-Lambiotte, Yacine ORCID: 0000-0003-1123-4788, Duval, Xavier, Laouénan, Cédric ORCID: 0000-0002-3681-6314, COVID-STORM Clinicians, , COVID Clinicians, , Imagine COVID Group, , French COVID Cohort Study Group, , CoV-Contact Cohort, , Amsterdam UMC Covid-19 Biobank, , COVID Human Genetic Effort, , NIAID-USUHS/TAGC COVID Immunity Group, , Snow, Andrew L ORCID: 0000-0002-8728-6691, Dalgard, Clifton L ORCID: 0000-0003-2025-8239, Milner, Joshua D, Vinh, Donald C ORCID: 0000-0003-1347-7767, Mogensen, Trine H ORCID: 0000-0002-1853-9704, Marr, Nico, Spaan, András N ORCID: 0000-0001-5981-7259, Boisson, Bertrand ORCID: 0000-0001-5240-3555, Boisson, Bertrand ORCID: 0000-0002-1927-7072, Boisson-Dupuis, Stéphanie ORCID: 0000-0002-7115-116X, Bustamante, Jacinta ORCID: 0000-0002-3439-2482, Puel, Anne ORCID: 0000-0003-2603-0323, Ciancanelli, Michael J ORCID: 0000-0002-4623-852X, Meyts, Isabelle ORCID: 0000-0003-1214-0302, Maniatis, Tom ORCID: 0000-0002-2722-8633, Soumelis, Vassili, Amara, Ali ORCID: 0000-0002-0283-1815, Nussenzweig, Michel ORCID: 0000-0003-0592-8564, García-Sastre, Adolfo ORCID: 0000-0002-6551-1827, Krammer, Florian ORCID: 0000-0003-4121-776X, Pujol, Aurora ORCID: 0000-0002-9606-0600, Duffy, Darragh ORCID: 0000-0002-8875-2308, Lifton, Richard P, Zhang, Shen-Ying, Gorochov, Guy ORCID: 0000-0003-2097-9677, Béziat, Vivien ORCID: 0000-0002-4020-824X, Jouanguy, Emmanuelle ORCID: 0000-0002-7358-9157, Sancho-Shimizu, Vanessa ORCID: 0000-0002-3519-0727, Rice, Charles M, Abel, Laurent ORCID: 0000-0001-7016-6493, Notarangelo, Luigi D ORCID: 0000-0002-8335-0262, Cobat, Aurélie ORCID: 0000-0001-7209-6257, Su, Helen C ORCID: 0000-0002-5582-9110 and Casanova, Jean-Laurent ORCID: 0000-0002-7782-4169 (2020) Inborn errors of type I IFN immunity in patients with life-threatening COVID-19. Science (New York, N.Y.), 370 (6515). eabd4570-.