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Yedida, Govindaraju, Milani, Mateus, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019)
Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis.
CELL DEATH & DISEASE, 10 (7).
521-.
Butterworth, Michael, Pettitt, Andrew, Varadarajan, Shankar ORCID: 0000-0002-8827-6567 and Cohen, Gerald M
(2016)
BH3 profiling and a toolkit of BH3-mimetic drugs predict anti-apoptotic dependence of cancer cells.
BRITISH JOURNAL OF CANCER, 114 (6).
pp. 638-641.
Greaves, Georgia, Milani, Mateus, Butterworth, Michael, Carter, Rachel J, Byrne, Dominic P, Eyers, Patrick A ORCID: 0000-0002-9220-2966, Luo, Xu, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019)
BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X-L.
CELL DEATH AND DIFFERENTIATION, 26 (6).
pp. 1037-1047.
Milani, Mateus, Beckett, Alison J ORCID: 0000-0001-8377-325X, Al-Zebeeby, Aoula, Luo, Xu, Prior, Ian A ORCID: 0000-0002-4055-5161, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019)
DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis.
Cell death discovery, 5 (1).
p. 117.
Milani, Mateus, Byrne, Dominic P, Greaves, Georgia, Butterworth, Michael, Cohen, Gerald M, Eyers, Patrick A ORCID: 0000-0002-9220-2966 and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2018)
DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis.
Cell Death and Disease, 8 (1).
e2552-.
Carter, Rachel J, Milani, Mateus, Butterworth, Michael, Alotibi, Ahoud, Harper, Nicholas, Yedida, Govindaraju, Greaves, Georgia, Al-Zebeeby, Aoula, Jorgensen, Andrea L ORCID: 0000-0002-6977-9337, Schache, Andrew G ORCID: 0000-0001-9466-6038 et al (show 7 more authors)
(2019)
Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck.
Cell Death and Disease, 10 (12).
912-.
Galluzzi, Lorenzo, Vitale, Ilio, Aaronson, Stuart A, Abrams, John M, Adam, Dieter, Agostinis, Patrizia, Alnemri, Emad S, Altucci, Lucia, Amelio, Ivano, Andrews, David W et al (show 159 more authors)
(2018)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
CELL DEATH AND DIFFERENTIATION, 25 (3).
pp. 486-541.
Carter, Rachel J, Milani, Mateus, Beckett, Alison J ORCID: 0000-0001-8377-325X, Liu, Shiyu, Prior, Ian A ORCID: 0000-0002-4055-5161, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2022)
Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis.
CELL DEATH & DISEASE, 13 (5).
436-.
Casara, Patrick, Davidson, James, Claperon, Audrey, Le Toumelin-Braizat, Gaëtane, Vogler, Meike ORCID: 0000-0003-2650-586X, Bruno, Alain, Chanrion, Maïa, Lysiak-Auvity, Gaëlle, Le Diguarher, Thierry, Starck, Jérôme-Benoît et al (show 28 more authors)
(2018)
S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Oncotarget, 9 (28).
pp. 20075-20088.
Henz, Kristina, Al-Zebeeby, Aoula, Basoglu, Marion, Fulda, Simone, Cohen, Gerald M, Varadarajan, Shankar ORCID: 0000-0002-8827-6567 and Vogler, Meike
(2019)
Selective BH3-mimetics targeting BCL-2, BCL-X<sub>L</sub> or MCL-1 induce severe mitochondrial perturbations.
BIOLOGICAL CHEMISTRY, 400 (2).
pp. 181-185.
Al-Zebeeby, Aoula, Vogler, Meike, Milani, Mateus, Richards, Caitlin, Alotibi, Ahoud, Greaves, Georgia, Dyer, Martin JS, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2019)
Targeting Intermediary Metabolism Enhances The Efficacy Of BH3 Mimetic Therapy In Haematological Malignancies.
Haematologica: the hematology journal, 104 (5).
pp. 1016-1025.
Al-Zebeeby, Aoula, Vogler, Meike, Milani, Mateus, Richards, Caitlin, Alotibi, Ahoud, Greaves, Georgia, Dyer, Martin JS, Cohen, Gerald M and Varadarajan, Shankar ORCID: 0000-0002-8827-6567
(2018)
Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in haematological malignancies.
Haematologica: the hematology journal.