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Dinkova-Kostova, Albena T and Copple, Ian M ORCID: 0000-0003-4101-1913 (2023) Advances and challenges in therapeutic targeting of NRF2. TRENDS IN PHARMACOLOGICAL SCIENCES, 44 (3). pp. 137-149.

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Copple, Ian M ORCID: 0000-0003-4101-1913, den Hollander, Wouter, Callegaro, Giulia, Mutter, Fiona E, Maggs, James L, Schofield, Amy L, Rainbow, Lucille ORCID: 0000-0003-0447-6885, Fang, Yongxiang ORCID: 0000-0002-4514-5292, Sutherland, Jeffrey J, Ellis, Ewa C et al (show 6 more authors) , Ingelman-Sundberg, Magnus, Fenwick, Stephen W, Goldring, Christopher E, van de Water, Bob, Stevens, James L and Park, B Kevin ORCID: 0000-0001-8384-824X (2019) Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury. Archives of Toxicology, 93 (2). pp. 385-399.

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Ogese, Monday O ORCID: 0000-0002-1873-4032, Faulkner, Lee, Jenkins, Roz E, French, Neil S ORCID: 0000-0002-9376-3482, Copple, Ian M ORCID: 0000-0003-4101-1913, Antoine, Daniel J, Elmasry, Mohamed, Malik, Hasan, Goldring, Christopher E, Park, Brian Kevin ORCID: 0000-0001-8384-824X et al (show 2 more authors) , Betts, Catherine J and Naisbitt, Dean J (2017) Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells. TOXICOLOGICAL SCIENCES, 158 (1). pp. 76-89.

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Wong, Michael HL, Bryan, Holly K, Copple, Ian M ORCID: 0000-0003-4101-1913, Jenkins, Rosalind E, Chiu, Pak Him, Bibby, Jaclyn, Berry, Neil G ORCID: 0000-0003-1928-0738, Kitteringham, Neil R, Goldring, Christopher E, O'Neill, Paul M ORCID: 0000-0003-4338-0317 et al (show 1 more authors) and Park, B Kevin ORCID: 0000-0001-8384-824X (2016) Design and Synthesis of Irreversible Analogues of Bardoxolone Methyl for the Identification of Pharmacologically Relevant Targets and Interaction Sites. JOURNAL OF MEDICINAL CHEMISTRY, 59 (6). pp. 2396-2409.

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Copple, Ian M ORCID: 0000-0003-4101-1913, Mercer, Amy E ORCID: 0000-0002-7399-8655, Firman, James, Donegan, Gail, Herpers, Bram, Wong, Michael HL, Chadwick, James, Bringela, Andreia D, Cristiano, Maria LS, van de Water, Bob et al (show 3 more authors) , Ward, Stephen A, O'Neill, Paul M ORCID: 0000-0003-4338-0317 and Park, B Kevin ORCID: 0000-0001-8384-824X (2012) Examination of the Cytotoxic and Embryotoxic Potential and Underlying Mechanisms of Next-Generation Synthetic Trioxolane and Tetraoxane Antimalarials. MOLECULAR MEDICINE, 18 (7). pp. 1045-1055.

Copple, Ian M ORCID: 0000-0003-4101-1913, Park, B Kevin ORCID: 0000-0001-8384-824X and Goldring, Christopher E (2021) Gene signatures reduce the stress of preclinical drug hepatotoxicity screening. Hepatology (Baltimore, Md.), 74 (1). pp. 513-515.

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Ghallab, Ahmed, Hassan, Reham, Hofmann, Ute, Friebel, Adrian, Hobloss, Zaynab, Brackhagen, Lisa, Begher-Tibbe, Brigitte, Myllys, Maiju, Reinders, Joerg, Overbeck, Nina et al (show 25 more authors) , Sezgin, Selahaddin, Zuehlke, Sebastian, Seddek, Abdel-Latif, Murad, Walaa, Brecklinghaus, Tim, Kappenberg, Franziska, Rahnenfuehrer, Joerg, Gonzalez, Daniela, Goldring, Christopher, Copple, Ian M ORCID: 0000-0003-4101-1913, Marchan, Rosemarie, Longerich, Thomas, Vucur, Mihael, Luedde, Tom, Urban, Stephan, Canbay, Ali, Schreiter, Thomas, Trauner, Michael, Akakpo, Jephte Y, Olyaee, Mojtaba, Curry, Steven C, Sowa, Jan-Peter, Jaeschke, Hartmut, Hoehme, Stefan and Hengstler, Jan G (2022) Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity. JOURNAL OF HEPATOLOGY, 77 (1). pp. 71-83.

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Weaver, Richard J, Blomme, Eric A, Chadwick, Amy E ORCID: 0000-0002-7399-8655, Copple, Ian M ORCID: 0000-0003-4101-1913, Gerets, Helga HJ, Goldring, Christopher E, Guillouzo, Andre, Hewitt, Philip G, Ingelman-Sundberg, Magnus, Jensen, Klaus Gjervig et al (show 12 more authors) , Juhila, Satu, Klingmueller, Ursula, Labbe, Gilles, Liguori, Michael J, Lovatt, Cerys A, Morgan, Paul, Naisbitt, Dean J, Pieters, Raymond HH, Snoeys, Jan, van de Water, Bob, Williams, Dominic P ORCID: 0000-0002-0758-3152 and Park, B Kevin ORCID: 0000-0001-8384-824X (2020) Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models. NATURE REVIEWS DRUG DISCOVERY, 19 (2). pp. 131-148.

Gregory, Georgina L and Copple, Ian M ORCID: 0000-0003-4101-1913 (2023) Modulating the expression of tumor suppressor genes using activating oligonucleotide technologies as a therapeutic approach in cancer. MOLECULAR THERAPY-NUCLEIC ACIDS, 31. pp. 211-223.

Copple, Ian M ORCID: 0000-0003-4101-1913, Dinkova-Kostova, Albena T, Kensler, Thomas W, Liby, Karen T and Wigley, W Christian (2017) NRF2 as an Emerging Therapeutic Target. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017. 8165458-.

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Lister, Adam, Bourgeois, Soline, Silva, Pedro H Imenez, Rubio-Aliaga, Isabel, Marbet, Philippe, Walsh, Joanne, Shelton, Luke M, Keller, Bettina, Verrey, Francois, Devuyst, Olivier et al (show 6 more authors) , Giesbertz, Pieter, Daniel, Hannelore, Goldring, Christopher E, Copple, Ian M ORCID: 0000-0003-4101-1913, Wagner, Carsten A and Odermatt, Alex (2018) NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis. SCIENTIFIC REPORTS, 8 (1). 5629-.

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Chan, Benjamin KY, Elmasry, Mohamed, Forootan, Shiva S, Russomanno, Giusy ORCID: 0000-0002-3378-5524, Bunday, Tobias M, Zhang, Fang, Brillant, Nathalie, Lewis, Philip J Starkey, Aird, Rhona, Ricci, Emanuele ORCID: 0000-0001-9751-0661 et al (show 14 more authors) , Andrews, Timothy D, Sison-Young, Rowena L, Schofield, Amy L, Fang, Yongxiang ORCID: 0000-0002-4514-5292, Lister, Adam, Sharkey, Jack W, Poptani, Harish ORCID: 0000-0002-0593-3235, Kitteringham, Neil R, Forbes, Stuart J, Malik, Hassan Z, Fenwick, Stephen W, Park, B Kevin ORCID: 0000-0001-8384-824X, Goldring, Christopher E and Copple, Ian M ORCID: 0000-0003-4101-1913 (2021) Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration. HEPATOLOGY, 74 (2). pp. 973-986.

Forootan, Shiva S, Mutter, Fiona E, Kipar, Anja ORCID: 0000-0001-7289-3459, Iwawaki, Takao, Francis, Ben ORCID: 0000-0002-2130-5976, Goldring, Christopher E, Park, B Kevin ORCID: 0000-0001-8384-824X and Copple, Ian M ORCID: 0000-0003-4101-1913 (2017) Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity. SCIENTIFIC REPORTS, 7 (1).

Clarke, Jessica L, Murray, James B, Park, B Kevin ORCID: 0000-0001-8384-824X and Copple, Ian M ORCID: 0000-0003-4101-1913 (2016) Roles of Nrf2 in drug and chemical toxicity. Current Opinion in Toxicology, 1. pp. 104-110.

Galea, Ian, Copple, Ian M ORCID: 0000-0003-4101-1913, Howat, David W and Franklin, Stephen (2019) SFX-01 reduces residual disability after experimental autoimmune encephalomyelitis. MULTIPLE SCLEROSIS AND RELATED DISORDERS, 30. pp. 257-261.

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Russomanno, Giusy ORCID: 0000-0002-3378-5524, Sison-Young, Rowena, Livoti, Lucia A, Coghlan, Hannah, Jenkins, Rosalind E, Kunnen, Steven J, Fisher, Ciarán P, Reddyhoff, Dennis, Gardner, Iain, Rehman, Adeeb H et al (show 11 more authors) , Fenwick, Stephen W, Jones, Andrew R, De Conchard, Guy Vermeil, Simonin, Gilles, Bertheux, Helene, Weaver, Richard J, Liguori, Michael J, Clausznitzer, Diana, Stevens, James L, Goldring, Christopher E and Copple, Ian M ORCID: 0000-0003-4101-1913 (2022) A systems approach reveals species differences in hepatic stress response capacity. [Preprint]

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Russomanno, Giusy ORCID: 0000-0002-3378-5524, Sison-Young, Rowena, Livoti, Lucia A, Coghlan, Hannah, Jenkins, Rosalind E, Kunnen, Steven J, Fisher, Ciaran P, Reddyhoff, Dennis, Gardner, Iain, Rehman, Adeeb H et al (show 12 more authors) , Fenwick, Stephen W, Jones, Andrew R ORCID: 0000-0001-6118-9327, Vermeil De Conchard, Guy, Simonin, Gilles, Bertheux, Helene, Weaver, Richard J, Johnson, Robert L, Liguori, Michael J, Clausznitzer, Diana, Stevens, James L, Goldring, Christopher E and Copple, Ian M ORCID: 0000-0003-4101-1913 (2023) A systems approach reveals species differences in hepatic stress response capacity. TOXICOLOGICAL SCIENCES, 196 (1). pp. 112-125.