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Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735 and Dalton, John P ORCID: 0000-0003-3829-9186 (2018) Advances in Fasciola hepatica research using ‘omics’ technologies. International Journal for Parasitology, 48 (5). pp. 321-331.

Pérez-Caballero, Raúl, Martínez-Moreno, F Javier, Corripio-Miyar, Yolanda, McNeilly, Tom N, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Dalton, John P, Zafra, Rafael, Pérez, José, Martínez-Moreno, Álvaro and Buffoni, Leandro (2021) Antigen-specific response of CD4+ T cells and hepatic lymph node cells to Fasciola hepatica-derived molecules at the early and late stage of the infection in sheep. Veterinary Research, 52 (1).

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Dorey, Amber, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Rooney, James, De Marco Verissimo, Carolina, López Corrales, Jesús, Jewhurst, Heather, Fazekas, Barbara, Calvani, Nichola Eliza Davies, Hamon, Siobhán, Gaughan, Siobhán et al (show 2 more authors) , Dalton, John P and Lalor, Richard (2021) Autonomous Non Antioxidant Roles for Fasciola hepatica Secreted Thioredoxin-1 and Peroxiredoxin-1. Frontiers in Cellular and Infection Microbiology, 11.

Mathew, Rency, Wunderlich, Juliane, Thivierge, Karine, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Dumont, Claire, Tilley, Leann, Rohrbach, Petra and Dalton, John P (2021) Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP). Scientific Reports, 11 (1).

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Allen, Katherine, LaCourse, James, Williams, Diana ORCID: 0000-0001-8186-7236, Paterson, Steve ORCID: 0000-0002-1307-2981 and Hodgkinson, Jane ORCID: 0000-0001-9152-8481 (2015) Characterisation of a novel panel of polymorphic microsatellite loci for the liver fluke, Fasciola hepatica, using a next generation sequencing approach. Infection, Genetics and Evolution, 32. pp. 298-304.

Hodgkinson, JE ORCID: 0000-0001-9152-8481, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Beesley, Nicola ORCID: 0000-0003-0557-1833, Hartley, Catherine, Allen, Katherine and Williams, Diana ORCID: 0000-0001-8186-7236 (2018) Clonal amplification of Fasciola hepatica in Galba truncatula: within and between isolate variation of triclabendazole-susceptible and -resistant clones. Parasites and Vectors, 11 (1).

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Robinson, Mark W ORCID: 0000-0001-7191-0034, Donnelly, Sheila ORCID: 0000-0003-2005-3698 and Dalton, John P (2021) Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver. BMC genomics, 22 (1). 46-.

Zhang, Xiao-Xuan, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Hu, Rui-Si ORCID: 0000-0003-0587-0542, Zheng, Wen-Bin, Sheng, Zhao-An, Zhang, Fu-Kai, Elsheikha, Hany M, Dalton, John P and Zhu, Xing-Quan (2019) Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts. BMC genomics, 20 (1). 729-.

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López Corrales, Jesús ORCID: 0000-0003-2996-7904, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, De Marco Verissimo, Carolina, Dorey, Amber ORCID: 0000-0001-5125-0382, Lalor, Richard, Jewhurst, Heather, McEvoy, Amanda, Diskin, Michael, Duffy, Catherine, Cosby, S Louise ORCID: 0000-0002-2617-8603 et al (show 2 more authors) , Keane, Orla M ORCID: 0000-0002-9507-2191 and Dalton, John Pius (2021) Diagnosis of sheep fasciolosis caused by Fasciola hepatica using cathepsin L enzyme-linked immunosorbent assays (ELISA). Veterinary parasitology, 298. 109517-.

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735 and Dalton, John Pius (2022) Exploiting Comparative Omics to Understand the Pathogenic and Virulence-Associated Protease: Anti-Protease Relationships in the Zoonotic Parasites <i>Fasciola hepatica</i> and <i>Fasciola gigantica</i>. GENES, 13 (10). 1854-.

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Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, de la Torre-Escudero, Eduardo, Trelis, Maria, Bernal, Dolores, Dufresne, Philippe J, Brennan, Gerard P, O'Neill, Sandra, Tort, Jose, Paterson, Steve ORCID: 0000-0002-1307-2981, Marcilla, Antonio et al (show 2 more authors) , Dalton, John P and Robinson, Mark W (2015) The Extracellular Vesicles of the Helminth Pathogen, <i>Fasciola hepatica</i>: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis. MOLECULAR & CELLULAR PROTEOMICS, 14 (12). pp. 3258-3273.

Murphy, Anna, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Lalor, Richard, O’Connell, Barry ORCID: 0000-0002-7438-3425, Robinson, Mark W, Gerlach, Jared, Joshi, Lokesh, Kilcoyne, Michelle, Dalton, John P and O’Neill, Sandra M ORCID: 0000-0002-0441-8055 (2020) Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity. PLOS Neglected Tropical Diseases, 14 (9). e0008626-e0008626.

Ravidà, Alessandra, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Aldridge, Allison M, Clarke, Paul, Thompson, Roisin, Gerlach, Jared Q, Kilcoyne, Michelle, Hokke, Cornelis H, Dalton, John P and O'Neill, Sandra M (2016) Fasciola hepatica Surface Tegument: Glycoproteins at the Interface of Parasite and Host. Molecular &amp; Cellular Proteomics, 15 (10). pp. 3139-3153.

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, McEvoy, Amanda, Corrales, Jesús López, Jewhurst, Heather, Calvani, Nichola Eliza Davies, De Marco Verissimo, Carolina, Dorey, Amber Louise, Keane, Orla M, Dalton, John Pius and Lalor, Richard (2023) Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection. Veterinary Parasitology, 323. p. 110049.

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Dalton, John Pius, Dufresne, Philippe J, La Course, James, Williams, Diana ORCID: 0000-0001-8186-7236, Hodgkinson, Jane ORCID: 0000-0001-9152-8481 and Paterson, Steve ORCID: 0000-0002-1307-2981 (2015) The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution. Genome Biology, 16 (1). 71-.

Tran, Nham, Ricafrente, Alison, To, Joyce, Lund, Maria, Marques, Tania M, Gama-Carvalho, Margarida, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Dalton, John P and Donnelly, Sheila (2021) Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses. Scientific Reports, 11 (1).

De Marco Verissimo, Carolina, Jewhurst, Heather L, Dobó, József, Gál, Péter, Dalton, John P and Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735 (2022) Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins. PLOS Pathogens, 18 (1). e1010226-e1010226.

De Marco Verissimo, Carolina ORCID: 0000-0003-1762-6387, Jewhurst, Heather L, Tikhonova, Irina G, Urbanus, Rolf T ORCID: 0000-0002-1601-9393, Maule, Aaron G, Dalton, John P ORCID: 0000-0003-3829-9186 and Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735 (2020) Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases. PLoS neglected tropical diseases, 14 (8). e0008510-.

De Marco Verissimo, Carolina, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Nilsson, Jonas, Mirgorodskaya, Ekaterina, Jin, Chunsheng, Karlsson, Niclas G and Dalton, John P (2023) Glycan complexity and heterogeneity of glycoproteins in somatic extracts and secretome of the infective stage of the helminth Fasciola hepatica. Molecular and Cellular Proteomics, 22 (12). p. 100684.

Ruiz-Campillo, Maria Teresa, Molina Hernandez, Veronica, Escamilla, Alejandro, Stevenson, Michael, Perez, Jose, Martinez-Moreno, Alvaro, Donnelly, Sheila, Dalton, John P and Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735 (2017) Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica. Scientific Reports, 7 (1).

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De Marco Verissimo, Carolina ORCID: 0000-0003-1762-6387, O'Brien, Carol, López Corrales, Jesús, Dorey, Amber, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Lalor, Richard, Doyle, Jack M, Field, Stephen, Masterson, Claire, Ribes Martinez, Eduardo et al (show 8 more authors) , Hughes, Gerry, Bergin, Colm, Walshe, Kieran, McNicholas, Bairbre, Laffey, John G, Dalton, John P, Kerr, Colm and Doyle, Sean (2021) Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests. Epidemiology and Infection, 149.

McVeigh, Paul ORCID: 0000-0003-1850-9692, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Garcia-Campos, Andres, Mulcahy, Grace, O'Neill, Sandra M, Maule, Aaron G ORCID: 0000-0003-0862-2667 and Dalton, John P ORCID: 0000-0003-3829-9186 (2018) In silico analyses of protein glycosylating genes in the helminth Fasciola hepatica (liver fluke) predict protein-linked glycan simplicity and reveal temporally-dynamic expression profiles. Scientific reports, 8 (1). 11700-.

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Jewhurst, Heather, McVeigh, Paul, Barbour, Tara, Maule, Aaron G, Tort, Jose, O'Neill, Sandra M, Robinson, Mark W, Donnelly, Sheila and Dalton, John P (2018) Infection by the Helminth Parasite Fasciola hepatica Requires Rapid Regulation of Metabolic, Virulence, and Invasive Factors to Adjust to Its Mammalian Host. Molecular &amp; Cellular Proteomics, 17 (4). pp. 792-809.

Dominguez, Maria Fernanda, González-Miguel, Javier ORCID: 0000-0003-4279-4761, Carmona, Carlos, Dalton, John P, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Tort, José ORCID: 0000-0003-3950-9982 and Siles-Lucas, Mar ORCID: 0000-0002-1257-2562 (2018) Low allelic diversity in vaccine candidates genes from different locations sustain hope for Fasciola hepatica immunization. Veterinary parasitology, 258. pp. 46-52.

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735 and Dalton, John P (2022) Omics tools enabling vaccine discovery against fasciolosis. TRENDS IN PARASITOLOGY, 38 (12). pp. 1068-1079.

Lalor, Richard, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Calvani, Nichola Eliza Davies, Dorey, Amber, Hamon, Siobhán, Corrales, Jesús López, Dalton, John Pius and De Marco Verissimo, Carolina ORCID: 0000-0003-1762-6387 (2021) Pathogenicity and virulence of the liver flukes<i>Fasciola hepatica</i>and<i>Fasciola</i><i>Gigantica</i>that cause the zoonosis Fasciolosis. Virulence, 12 (1). pp. 2839-2867.

De Marco Verissimo, Carolina ORCID: 0000-0003-1762-6387, López Corrales, Jesús, Dorey, Amber L, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Lalor, Richard, Calvani, Nichola Eliza Davies ORCID: 0000-0002-8787-6755, Jewhurst, Heather L, Flaus, Andrew, Doyle, Sean and Dalton, John P (2022) Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system. Epidemiology and Infection, 150. pp. 1-19.

Becerro-Recio, David, González-Miguel, Javier, Ucero, Alberto, Sotillo, Javier ORCID: 0000-0002-1443-7233, Martínez-Moreno, Álvaro, Pérez-Arévalo, José, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Dalton, John P and Siles-Lucas, Mar (2021) Recognition Pattern of the Fasciola hepatica Excretome/Secretome during the Course of an Experimental Infection in Sheep by 2D Immunoproteomics. Pathogens, 10 (6). p. 725.

Pritsch, Izanara C, Tikhonova, Irina G, Jewhurst, Heather L, Drysdale, Orla, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Molento, Marcelo B, Dalton, John P and Verissimo, Carolina De M ORCID: 0000-0003-1762-6387 (2020) Regulation of the Fasciola hepatica newly excysted juvenile cathepsin L3 (FhCL3) by its propeptide: a proposed ‘clamp-like’ mechanism of binding and inhibition. BMC Molecular and Cell Biology, 21 (1).

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Shiels, Jenna ORCID: 0000-0001-7462-7648, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Alvarado, Raquel ORCID: 0000-0001-7250-2200, Thivierge, Karine, Cotton, Sophie, Gonzales Santana, Bibiana, To, Joyce ORCID: 0000-0003-3482-4369, Donnelly, Sheila ORCID: 0000-0003-2005-3698, Taggart, Clifford C, Weldon, Sinead ORCID: 0000-0001-5628-6624 et al (show 1 more authors) and Dalton, John P (2020) Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs). PLoS neglected tropical diseases, 14 (7). e0008470-.

Williams, Tijana, Karim, Mohammad Jahirul, Uddin, Shihab, Jahan, Sharmin, ASM, Sultan Mahmood, Forbes, Shaun P, Hooper, Anna, Taylor, Mark J and Kelly-Hope, Louise A ORCID: 0000-0002-3330-7629 (2023) Socio-economic and environmental factors associated with high lymphatic filariasis morbidity prevalence distribution in Bangladesh. PLOS Neglected Tropical Diseases, 17 (7). e0011457-e0011457.

Ricafrente, Alison, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Nguyen, Hieu, Dalton, John P, Tran, Nham and Donnelly, Sheila (2022) Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatica. BMC Genomics, 23 (1).

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de la Torre-Escudero, Eduardo, Gerlach, Jared Q, Bennett, Adam PS, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Jewhurst, Heather L, Huson, Kathryn M, Joshi, Lokesh, Kilcoyne, Michelle, O’Neill, Sandra, Dalton, John P et al (show 1 more authors) and Robinson, Mark W ORCID: 0000-0001-7191-0034 (2019) Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells. PLOS Neglected Tropical Diseases, 13 (1). e0007087-e0007087.

Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Drysdale, Orla, López Corrales, Jesús ORCID: 0000-0003-2996-7904, Corripio-Miyar, Yolanda ORCID: 0000-0002-1344-7405, De Marco Verissimo, Carolina, Jewhurst, Heather ORCID: 0000-0003-4630-7027, Smith, David, Lalor, Richard, McNeilly, Tom N ORCID: 0000-0001-6469-0512 and Dalton, John P ORCID: 0000-0003-3829-9186 (2022) Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth Fasciola hepatica. Vaccines, 10 (2). p. 155.

Garcia-Campos, Andres, Ravidà, Alessandra, Nguyen, D Linh, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Dalton, John P, Hokke, Cornelis H, O’Neill, Sandra and Mulcahy, Grace (2016) Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans. PLOS Neglected Tropical Diseases, 10 (5). e0004688-e0004688.

Calvani, Nichola Eliza Davies, Verissimo, Carolina De Marco, Jewhurst, Heather Louise, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Flaus, Andrew and Dalton, John Pius (2022) Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite <i>Fasciola hepatica</i> Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during Growth and Development. ANTIOXIDANTS, 11 (10). 1968-.

Smith, David, Tikhonova, Irina G, Jewhurst, Heather L, Drysdale, Orla C, Dvořák, Jan, Robinson, Mark W, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735 and Dalton, John P (2016) Unexpected Activity of a Novel Kunitz-type Inhibitor. Journal of Biological Chemistry, 291 (37). pp. 19220-19234.

Barbour, Tara, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Lalor, Richard, Dalton, John Pius ORCID: 0000-0003-3829-9186 and De Marco Verissimo, Carolina (2021) The Zoonotic Helminth Parasite Fasciola hepatica: Virulence-Associated Cathepsin B and Cathepsin L Cysteine Peptidases Secreted by Infective Newly Excysted Juveniles (NEJ). Animals, 11 (12). p. 3495.

Smith, David, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Jewhurst, Heather, Tikhonova, Irina G and Dalton, John P (2020) An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica. Scientific Reports, 10 (1).

Vorel, Jiri, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Roudnicky, Pavel, Ilgova, Jana, Jedlickova, Lucie, Dalton, John P, Mikes, Libor, Gelnar, Milan and Kasny, Martin (2021) <i>Eudiplozoon nipponicum</i> (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling. BMC GENOMICS, 22 (1). 274-.

Beesley, Nicola J ORCID: 0000-0003-0557-1833, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Allen, Katherine, Hoyle, Rebecca C, Spithill, Terry W, La Course, E James, Williams, Diana JL ORCID: 0000-0001-8186-7236, Paterson, Steve ORCID: 0000-0002-1307-2981 and Hodgkinson, Jane E ORCID: 0000-0001-9152-8481 (2023) A major locus confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance. PLOS Pathogens, 19 (1). e1011081-e1011081.

Corrales, Jesús López, McEvoy, Amanda, Lalor, Richard, Cwiklinski, Krystyna ORCID: 0000-0001-5577-2735, Doyle, Sean, Parkinson, Michael, Keane, Orla M, Dalton, John Pius and Dorey, Amber Louise (2023) The use of cathepsin L1 (FhCL1) serological ELISA in sentinel screening for liver fluke on sheep farms. Veterinary Parasitology: Regional Studies and Reports, 45. p. 100924.