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Elliot, Emillie, Neary, MG ORCID: 0000-0002-4960-2139, Else, Laura, Khoo, Saye ORCID: 0000-0002-2769-0967, Moyle, Graeme, Carr, Dan, Owen, Andrew ORCID: 0000-0002-9819-7651 and Boffito, Marta
(2018)
ABCG2 rs2231142 and NR1I2 rs2472677 influence dolutegravir concentrations in plasma.
In: CROI, Boston, MA, USA.
Thompson, Beth, Dilly-Penchala, Sujan, Amara, Alieu ORCID: 0000-0002-1137-2948, Reynolds, Helen ORCID: 0000-0001-7443-4520, Khoo, Saye ORCID: 0000-0002-2769-0967 and Else, Laura
(2023)
Application of novel plasma separation filter cards for quantification of nucleoside/nucleotide reverse transcriptase inhibitor di/triphosphates in dried blood spot using LC-MS.
BIOANALYSIS, 15 (13).
pp. 739-756.
Olagunju, Adeniyi, Bolaji, Oluseye, Amara, Alieu, Waitt, Catriona, Else, Laura, Adejuyigbe, Ebunoluwa, Siccardi, Marco, Back, David, Khoo, Saye and Owen, Andrew
(2015)
Breast milk pharmacokinetics of efavirenz and breastfed infants' exposure in genetically-defined subgroups of mother-infant pairs: an observational study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
Fox, Julie, Tiraboschi, Juan M, Herrera, Carolina ORCID: 0000-0003-3701-752X, Else, Laura, Egan, Deirdre, Dickinson, Laura ORCID: 0000-0001-5557-9396, Jackson, Akil ORCID: 0000-0002-4574-544X, Olejniczak, Natalia, Back, David, Khoo, Saye ORCID: 0000-0002-2769-0967 et al (show 2 more authors)
(2016)
Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis.
Journal of acquired immune deficiency syndromes (1999), 73 (3).
pp. 252-257.
Winston, Alan, Amin, Janaki, Clarke, Amanda, Else, Laura, Amara, Alieu ORCID: 0000-0002-1137-2948, Owen, Andrew ORCID: 0000-0002-9819-7651, Barber, Tristan, Jessen, Heiko, Avinghsanon, Anchalee, Chetchotisakd, Ploenchan et al (show 4 more authors)
(2015)
Cerebrospinal Fluid Exposure of Efavirenz and Its Major Metabolites When Dosed at 400 mg and 600 mg Once Daily: A Randomized Controlled Trial.
CLINICAL INFECTIOUS DISEASES, 60 (7).
pp. 1026-1032.
Dickinson, Laura ORCID: 0000-0001-5557-9396, Amin, Janaki, Else, Laura, Boffito, Marta, Egan, Deirdre, Owen, Andrew ORCID: 0000-0002-9819-7651, Khoo, Saye ORCID: 0000-0002-2769-0967, Back, David, Orrell, Catherine, Clarke, Amanda et al (show 6 more authors)
(2016)
Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naive HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study.
CLINICAL PHARMACOKINETICS, 55 (7).
pp. 861-873.
Challenger, Elizabeth ORCID: 0000-0002-8978-6067, Penchala, Sujan Dilly, Hale, Colin, Fitzgerald, Richard, Walker, Lauren ORCID: 0000-0002-3827-4387, Reynolds, Helen ORCID: 0000-0001-7443-4520, Chiong, Justin, Fletcher, Tom, Khoo, Saye and Else, Laura
(2023)
Development and validation of an LC-MS/MS method for quantification of favipiravir in human plasma.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 233.
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Waitt, Catriona ORCID: 0000-0003-0134-5855, Penchala, Sujan Diliiy, Olagunju, Adeniyi ORCID: 0000-0002-6588-5749, Amara, Alieu ORCID: 0000-0002-1137-2948, Else, Laura, Lamorde, Mohammed and Khoo, Saye ORCID: 0000-0002-2769-0967
(2017)
Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC-MS/MS.
Journal of Chromatography B, 1060.
pp. 300-307.
Olagunju, Adeniyi ORCID: 0000-0002-6588-5749, Bolaji, Oluseye O, Amara, Alieu ORCID: 0000-0002-1137-2948, Waitt, Catriona ORCID: 0000-0003-0134-5855, Else, Laura, Soyinka, Julius, Adeagbo, Babatunde, Adejuyigbe, Ebunoluwa, Siccardi, Marco ORCID: 0000-0002-3539-7867, Back, David et al (show 2 more authors)
(2015)
Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70 (2).
pp. 555-561.
Elliot, Emilie, Amara, Alieu ORCID: 0000-0002-1137-2948, Jackson, Akil ORCID: 0000-0002-4574-544X, Moyle, Graeme, Else, Laura, Khoo, Saye ORCID: 0000-0002-2769-0967, Back, David, Owen, Andrew ORCID: 0000-0002-9819-7651 and Boffito, Marta
(2016)
Dolutegravir and elvitegravir plasma concentrations following cessation of drug intake.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71 (4).
pp. 1031-1036.
Herrera, Carolina, Serwanga, Jennifer, Else, Laura, Limakatso, Lebina, Opoka, Daniel, Ssemata, Andrew S, Pillay, Azure-Dee, Namubiru, Patricia, Seiphetlo, Thabiso B, Odoch, Geoffrey et al (show 19 more authors)
(2023)
Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial.
EBIOMEDICINE, 93.
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Walimbwa, Stephen I, Lamorde, Mohammed, Waitt, Catriona ORCID: 0000-0003-0134-5855, Kaboggoza, Julian ORCID: 0000-0001-9510-0474, Else, Laura, Byakika-Kibwika, Pauline, Amara, Alieu ORCID: 0000-0002-1137-2948, Gini, Joshua, Winterberg, Markus, Chiong, Justin ORCID: 0000-0001-8063-6399 et al (show 2 more authors)
(2019)
Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63 (2).
e01310-e01318.
Reynolds, Helen E, Chrdle, Ales, Egan, Deirdre, Chaponda, Mas, Else, Laura, Chiong, Justin ORCID: 0000-0001-8063-6399, Back, David J and Khoo, Saye H
(2015)
Effect of intermittent rifampicin on the pharmacokinetics and safety of raltegravir.
The Journal of antimicrobial chemotherapy, 70 (2).
pp. 550-554.
Harvala, Heli, Reynolds, Claire, Ijaz, Samreen, Maddox, Vicki, Penchala, Sujan Dilly, Amara, Alieu ORCID: 0000-0002-1137-2948, Else, Laura, Brailsford, Susan and Khoo, Saye ORCID: 0000-0002-2769-0967
(2022)
Evidence of HIV pre-exposure or post-exposure prophylaxis (PrEP/PEP) among blood donors: a pilot study, England June 2018 to July 2019.
SEXUALLY TRANSMITTED INFECTIONS, 98 (2).
pp. 132-135.
Elliot, Emilie R, Neary, Megan ORCID: 0000-0002-4960-2139, Else, Laura, Khoo, Saye ORCID: 0000-0002-2769-0967, Moyle, Graeme, Carr, Daniel F, Wang, Xinzhu, Mcclure, Myra, Boffito, Marta and Owen, Andrew ORCID: 0000-0002-9819-7651
(2020)
Genetic influence of <i>ABCG2, UGT1A1</i> and <i>NR1I2</i> on dolutegravir plasma pharmacokinetics.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75 (5).
pp. 1259-1266.
Dickinson, Laura ORCID: 0000-0001-5557-9396, Walimbwa, Stephen, Singh, Yashna, Kaboggoza, Julian, Kintu, Kenneth, Sihlangu, Mary, Coombs, Julie-Anne, Malaba, Thokozile R, Byamugisha, Josaphat, Pertinez, Henry et al (show 11 more authors)
(2021)
Infant Exposure to Dolutegravir Through Placental and Breast Milk Transfer: A Population Pharmacokinetic Analysis of DolPHIN-1.
CLINICAL INFECTIOUS DISEASES, 73 (5).
E1200-E1207.
McGowan, Ian, Dezzutti, Charlene S, Siegel, Aaron, Engstrom, Jarret, Nikiforov, Alexiy, Duffill, Kathryn, Shetler, Cory, Richardson-Harman, Nicola, Abebe, Kaleab, Back, David et al (show 12 more authors)
(2016)
Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment.
LANCET HIV, 3 (12).
E569-E578.
Petkov, Stefan, Herrera, Carolina, Else, Laura, Mugaba, Susan, Namubiru, Patricia, Odoch, Geoffrey, Opoka, Daniel, Pillay, Azure-Dee AP, Seiphetlo, Thabiso B, Serwanga, Jennifer et al (show 9 more authors)
(2022)
Mobilization of systemic CCL4 following HIV pre-exposure prophylaxis in young men in Africa.
FRONTIERS IN IMMUNOLOGY, 13.
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Cranston, Ross D, Dezzutti, Charlene S, Siegel, Aaron, Engstrom, Jarret, Shetler, Cory, Richardson-Harman, Nicola, Abebe, Kaleab Z, Back, David, Else, Laura, Egan, Deidre et al (show 7 more authors)
(2019)
A Multiple Dose Phase 1 Assessment of Rilpivirine Long Acting in a Model of Preexposure Prophylaxis Against HIV.
AIDS RESEARCH AND HUMAN RETROVIRUSES, 35 (9).
pp. 794-804.
Elliot, Emilie R, Amara, Alieu ORCID: 0000-0002-1137-2948, Pagani, Nicole, Else, Laura, Moyle, Graeme, Schoolmeesters, Alex, Higgs, Chris, Khoo, Saye ORCID: 0000-0002-2769-0967 and Boffito, Marta
(2017)
Once-daily atazanavir/cobicistat and darunavir/cobicistat exposure over 72 h post-dose in plasma, urine and saliva: contribution to drug pharmacokinetic knowledge (vol 72, pg 2035, 2017).
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 72 (7).
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Walker, Lauren E ORCID: 0000-0002-3827-4387, FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin et al (show 23 more authors)
(2022)
An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 111 (3).
pp. 585-594.
Dickinson, Laura, Amin, J, Else, Laura, Boffito, M, Egan, Deirdre, Owen, Andrew ORCID: 0000-0002-9819-7651, Khoo, Saye ORCID: 0000-0002-2769-0967, Back, David, Orrell, C, Clarke, A et al (show 6 more authors)
(2015)
Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naïve HIV-Infected Patients: Results of the ENCORE1 Study.
Clinical pharmacology and therapeutics, 98 (4).
pp. 406-416.
Fox, Julie, Tiraboschi, Juan M, Herrera, Carolina, Else, Laura, Egan, Deirdre, Dickinson, Laura ORCID: 0000-0001-5557-9396, Jackson, Akil, Olejniczak, Natalia, Back, David, Khoo, Saye ORCID: 0000-0002-2769-0967 et al (show 2 more authors)
(2016)
Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 73 (3).
pp. 252-257.
Herrera, Carolina, Lwanga, Julianne, Lee, Ming, Mantori, Suna, Amara, Alieu ORCID: 0000-0002-1137-2948, Else, Laura, Penchala, Sujan Dilly, Egan, Deirdre, Challenger, Elizabeth ORCID: 0000-0002-8978-6067, Dickinson, Laura ORCID: 0000-0001-5557-9396 et al (show 4 more authors)
(2021)
Pharmacokinetic/pharmacodynamic investigation of raltegravir with or without lamivudine in the context of HIV-1 pre-exposure prophylaxis (PrEP).
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76 (8).
pp. 2129-2136.
Jackson, Akil ORCID: 0000-0002-4574-544X, Else, Laura, Higgs, Christopher, Karolia, Zeenat, Khoo, Saye ORCID: 0000-0002-2769-0967, Back, David, Devitt, Emma, Pozniak, Anton and Boffito, Marta
(2018)
Pharmacokinetics and pharmacodynamics of the nucleoside sparing dual regimen containing rilpivirine plus darunavir/ritonavir in treatment-naive HIV-1-infected individuals.
HIV CLINICAL TRIALS, 19 (1).
pp. 31-37.
Elliot, Emilie R, Cerrone, Maddalena, Challenger, Elizabeth ORCID: 0000-0002-8978-6067, Else, Laura, Amara, Alieu ORCID: 0000-0002-1137-2948, Bisdomini, Elisa, Khoo, Saye ORCID: 0000-0002-2769-0967, Owen, Andrew ORCID: 0000-0002-9819-7651 and Boffito, Marta
(2019)
Pharmacokinetics of dolutegravir with and without darunavir/cobicistat in healthy volunteers (vol 74, pg 149, 2019).
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 74 (5).
p. 1466.
Elliot, Emilie R, Cerrone, Maddalena, Else, Laura, Amara, Alieu ORCID: 0000-0002-1137-2948, Bisdomini, Elisa, Khoo, Saye ORCID: 0000-0002-2769-0967, Owen, Andrew ORCID: 0000-0002-9819-7651 and Boffito, Marta
(2019)
Pharmacokinetics of dolutegravir with and without darunavir/cobicistat in healthy volunteers.
The Journal of antimicrobial chemotherapy, 74 (1).
pp. 149-156.
FitzGerald, Richard, Dickinson, Laura ORCID: 0000-0001-5557-9396, Else, Laura, Fletcher, Thomas, Hale, Colin, Amara, Alieu ORCID: 0000-0002-1137-2948, Walker, Lauren ORCID: 0000-0002-3827-4387, Penchala, Sujan Dilly, Lyon, Rebecca, Shaw, Victoria ORCID: 0000-0002-0429-0186 et al (show 9 more authors)
(2022)
Pharmacokinetics of ss-d-N4-Hydroxycytidine, the Parent Nucleoside of Prodrug Molnupiravir, in Nonplasma Compartments of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
CLINICAL INFECTIOUS DISEASES, 75 (1).
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Dickinson, Laura ORCID: 0000-0001-5557-9396, Yapa, H Manisha, Jackson, Akil ORCID: 0000-0002-4574-544X, Moyle, Graeme, Else, Laura, Amara, Alieu ORCID: 0000-0002-1137-2948, Khoo, Saye ORCID: 0000-0002-2769-0967, Back, David, Karolia, Zeenat, Higgs, Chris et al (show 1 more authors)
(2015)
Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59 (10).
pp. 6080-6086.
Dickinson, Laura ORCID: 0000-0001-5557-9396, Bracchi, Margherita, Elliot, Emilie, Else, Laura, Khoo, Saye ORCID: 0000-0002-2769-0967, Back, David, Nelson, Mark and Boffito, Marta
(2016)
Population pharmacokinetics (PK) of dolutegravir (DTG) alone and following treatment switch.
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Else, Laura, Penchala, Sujan D, Pillay, Azure-Dee, Seiphetlo, Thabiso B, Lebina, Limakatso, Callebaut, Christian, Minhas, Suks, Morley, Roland, Rashid, Tina, Martinson, Neil et al (show 3 more authors)
(2022)
Pre-Clinical Evaluation of Tenofovir and Tenofovir Alafenamide for HIV-1 Pre-Exposure Prophylaxis in Foreskin Tissue.
PHARMACEUTICS, 14 (6).
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Molto, Jose, Graterol, Fredzzia, Curran, Adrian, Ramos, Natalia, Imaz, Arkaitz, Sandoval, Diego, Perez, Francisco, Bailon, Lucia, Khoo, Saye ORCID: 0000-0002-2769-0967, Else, Laura et al (show 1 more authors)
(2022)
Removal of doravirine by haemodialysis in people living with HIV with end-stage renal disease.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77 (7).
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Waitt, Catriona ORCID: 0000-0003-0134-5855, Orrell, Catherine, Walimbwa, Stephen, Singh, Yashna, Kintu, Kenneth, Simmons, Bryony, Kaboggoza, Julian ORCID: 0000-0001-9510-0474, Sihlangu, Mary, Coombs, Julie-Anne, Malaba, Thoko et al (show 13 more authors)
(2019)
Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study).
PLOS MEDICINE, 16 (9).
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Petkov, Stefan, Herrera, Carolina, Else, Laura, Lebina, Limakatso, Opoka, Daniel, Seiphetlo, Thabiso B, Ap Pillay, Azure-Dee, Mugaba, Susan, Namubiru, Patricia, Odoch, Geoffrey et al (show 9 more authors)
(2022)
Short-term oral pre-exposure prophylaxis against HIV-1 modulates the transcriptome of foreskin tissue in young men in Africa.
FRONTIERS IN IMMUNOLOGY, 13.
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Else, Laura, Back, David, Khoo, Saye H ORCID: 0000-0002-2769-0967 and Merry, Concepta
(2015)
Steady-state pharmacokinetics of rilpivirine under different meal conditions in HIV-1-infected Ugandan adults.
The Journal of Antimicrobial Chemotherapy, 70 (5).
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Abouyannis, Michael ORCID: 0000-0003-4856-4334, FitzGerald, Richard, Ngama, Mwanajuma, Mwangudzah, Hope ORCID: 0000-0003-1166-8965, Nyambura, Yvonne K, Ngome, Samson, Riako, Debra, Babu, Lawrence, Lewa, Frida, Else, Laura et al (show 10 more authors)
(2022)
TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).
Wellcome open research, 7.
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Maddox, Victoria, Reynolds, Claire, Amara, Alieu ORCID: 0000-0002-1137-2948, Else, Laura, Brailsford, Susan R, Khoo, Saye ORCID: 0000-0002-2769-0967 and Harvala, Heli
(2023)
Undeclared pre-exposure or post-exposure prophylaxis (PrEP/PEP) use among syphilis-positive blood donors, England, 2020 to 2021.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 28 (11).
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Penchala, Sujan Dilly, Fawcett, Sandra, Else, Laura, Egan, Deirdre, Amara, Alieu ORCID: 0000-0002-1137-2948, Elliot, Emilie, Challenger, Elizabeth ORCID: 0000-0002-8978-6067, Back, David, Boffito, Marta and Khoo, Saye ORCID: 0000-0002-2769-0967
(2016)
The development and application of a novel LC-MS/MS method for the measurement of Dolutegravir, Elvitegravir and Cobicistat in human plasma.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1027.
pp. 174-180.
Penchala, Sujan Dilly, Alagaratnam, Jasmini, Challenger, Elizabeth ORCID: 0000-0002-8978-6067, Amara, Alieu ORCID: 0000-0002-1137-2948, Else, Laura, Winston, Alan and Khoo, Saye ORCID: 0000-0002-2769-0967
(2020)
The development and validation of a novel LC-MS/MS method for the quantification of cenicriviroc in human plasma and cerebrospinal fluid.
BIOMEDICAL CHROMATOGRAPHY, 34 (1).
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Amara, Alieu ORCID: 0000-0002-1137-2948, Penchala, Sujan Dilly, Else, Laura, Hale, Colin, FitzGerald, Richard, Walker, Lauren ORCID: 0000-0002-3827-4387, Lyons, Rebecca, Fletcher, Tom and Khoo, Saye ORCID: 0000-0002-2769-0967
(2021)
The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite β-d-N4-hydroxycytidine in human plasma and saliva.
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Else, Laura
(2009)
The role of pharmacokinetics in optimising antiretroviral therapy in HIV-infected patients.
PhD thesis, University of Liverpool.