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Griffiths, Gareth O, FitzGerald, Richard, Jaki, Thomas, Corkhill, Andrea, Reynolds, Helen ORCID: 0000-0001-7443-4520, Ewings, Sean, Condie, Susannah, Tilt, Emma, Johnson, Lucy, Radford, Mike et al (show 27 more authors)
(2021)
AGILE: a seamless phase I/IIa platform for the rapid evaluation of candidates for COVID-19 treatment: an update to the structured summary of a study protocol for a randomised platform trial letter.
TRIALS, 22 (1).
487-.
Donovan-Banfield, I'ah ORCID: 0000-0002-5124-2427, Penrice-Randal, Rebekah ORCID: 0000-0002-0653-2097, Goldswain, Hannah ORCID: 0000-0003-4194-8714, Rzeszutek, Aleksandra M, Pilgrim, Jack, Bullock, Katie, Saunders, Geoffrey, Northey, Josh, Dong, Xiaofeng, Ryan, Yan ORCID: 0000-0002-4708-5350 et al (show 24 more authors)
(2022)
Characterisation of SARS-CoV-2 genomic variation in response to molnupiravir treatment in the AGILE Phase IIa clinical trial.
NATURE COMMUNICATIONS, 13 (1).
7284-.
Ranganath, Lakshminarayan R, Psarelli, Eftychia Eirini ORCID: 0000-0002-3102-0288, Arnoux, Jean-Baptiste, Braconi, Daniela, Briggs, Michael, Broijersen, Anders, Loftus, Nadia, Bygott, Helen, Cox, Trevor F, Davison, Andrew S ORCID: 0000-0001-5501-4475 et al (show 39 more authors)
(2020)
Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial.
The Lancet Diabetes and Endocrinology, 8 (9).
pp. 762-772.
Turner, Richard M ORCID: 0000-0002-7315-679X, Fontana, Vanessa ORCID: 0000-0002-0146-9113, Zhang, Jieying E ORCID: 0000-0003-1813-2207, Carr, Daniel, Yin, Peng, FitzGerald, Richard, Morris, Andrew P and Pirmohamed, Munir ORCID: 0000-0002-7534-7266
(2020)
A Genome‐wide Association Study of Circulating Levels of Atorvastatin and Its Major Metabolites.
Clinical Pharmacology and Therapeutics, 108 (2).
pp. 287-297.
Turner, Richard M ORCID: 0000-0002-7315-679X, Fontana, Vanessa ORCID: 0000-0002-0146-9113, FitzGerald, Richard, Morris, Andrew P and Pirmohamed, Munir ORCID: 0000-0002-7534-7266
(2020)
Investigating the clinical factors and comedications associated with circulating levels of atorvastatin and its major metabolites in secondary prevention.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 86 (1).
pp. 62-74.
Khoo, Saye H ORCID: 0000-0002-2769-0967, FitzGerald, Richard, Saunders, Geoffrey, Middleton, Calley, Ahmad, Shazaad, Edwards, Christopher J, Hadjiyiannakis, Dennis, Walker, Lauren ORCID: 0000-0002-3827-4387, Lyon, Rebecca, Shaw, Victoria ORCID: 0000-0002-0429-0186 et al (show 80 more authors)
(2022)
Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial.
The Lancet Infectious Diseases, 23 (2).
pp. 183-195.
Walker, Lauren E ORCID: 0000-0002-3827-4387, FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin et al (show 23 more authors)
(2022)
An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 111 (3).
pp. 585-594.
FitzGerald, Richard, Dickinson, Laura ORCID: 0000-0001-5557-9396, Else, Laura, Fletcher, Thomas, Hale, Colin, Amara, Alieu ORCID: 0000-0002-1137-2948, Walker, Lauren ORCID: 0000-0002-3827-4387, Penchala, Sujan Dilly, Lyon, Rebecca, Shaw, Victoria ORCID: 0000-0002-0429-0186 et al (show 9 more authors)
(2022)
Pharmacokinetics of ss-d-N4-Hydroxycytidine, the Parent Nucleoside of Prodrug Molnupiravir, in Nonplasma Compartments of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
CLINICAL INFECTIOUS DISEASES, 75 (1).
E525-E528.
Abouyannis, Michael ORCID: 0000-0003-4856-4334, FitzGerald, Richard, Ngama, Mwanajuma, Mwangudzah, Hope ORCID: 0000-0003-1166-8965, Nyambura, Yvonne K, Ngome, Samson, Riako, Debra, Babu, Lawrence, Lewa, Frida, Else, Laura et al (show 10 more authors)
(2022)
TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).
Wellcome open research, 7.
90-.
Amara, Alieu ORCID: 0000-0002-1137-2948, Penchala, Sujan Dilly, Else, Laura, Hale, Colin, FitzGerald, Richard, Walker, Lauren ORCID: 0000-0002-3827-4387, Lyons, Rebecca, Fletcher, Tom and Khoo, Saye ORCID: 0000-0002-2769-0967
(2021)
The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite β-d-N4-hydroxycytidine in human plasma and saliva.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 206.
114356-.