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Griffiths, Gareth, Fitzgerald, Richard, Jaki, Thomas, Corkhill, Andrea, Marwood, Ellice, Reynolds, Helen ORCID: 0000-0001-7443-4520, Stanton, Louise, Ewings, Sean, Condie, Susannah, Wrixon, Emma et al (show 7 more authors)
(2020)
AGILE-ACCORD: A Randomized, Multicentre, Seamless, Adaptive Phase I/II Platform Study to Determine the Optimal Dose, Safety and Efficacy of Multiple Candidate Agents for the Treatment of COVID-19: A structured summary of a study protocol for a randomised platform trial.
TRIALS, 21 (1).
544-.
Donovan-Banfield, I'ah ORCID: 0000-0002-5124-2427, Penrice-Randal, Rebekah ORCID: 0000-0002-0653-2097, Goldswain, Hannah ORCID: 0000-0003-4194-8714, Rzeszutek, Aleksandra M, Pilgrim, Jack, Bullock, Katie, Saunders, Geoffrey, Northey, Josh, Dong, Xiaofeng, Ryan, Yan ORCID: 0000-0002-4708-5350 et al (show 24 more authors)
(2022)
Characterisation of SARS-CoV-2 genomic variation in response to molnupiravir treatment in the AGILE Phase IIa clinical trial.
NATURE COMMUNICATIONS, 13 (1).
7284-.
Crabb, Simon, Wickens, Robin, Jane-Bibby, Sarah, Dunkley, Denise, Lawrence, Megan, Knight, Allen, Jones, Robert ORCID: 0000-0001-5608-001X, Birtle, Alison, Huddart, Robert, Linch, Mark et al (show 5 more authors)
(2023)
Evaluating atezolizumab in patients with urinary tract squamous cell carcinoma (AURORA): study protocol for a single arm, open-label, multicentre, phase II clinical trial.
BMC cancer, 23 (1).
p. 885.
Khoo, Saye H ORCID: 0000-0002-2769-0967, FitzGerald, Richard, Saunders, Geoffrey, Middleton, Calley, Ahmad, Shazaad, Edwards, Christopher J, Hadjiyiannakis, Dennis, Walker, Lauren ORCID: 0000-0002-3827-4387, Lyon, Rebecca, Shaw, Victoria ORCID: 0000-0002-0429-0186 et al (show 80 more authors)
(2022)
Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial.
The Lancet Infectious Diseases, 23 (2).
pp. 183-195.
Fennell, Dean A, Ewings, Sean, Ottensmeier, Christian ORCID: 0000-0003-3619-1657, Califano, Raffaele, Hanna, Gerard G, Hill, Kayleigh, Danson, Sarah, Steele, Nicola, Nye, Mavis, Johnson, Lucy et al (show 11 more authors)
(2021)
Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial.
LANCET ONCOLOGY, 22 (11).
pp. 1530-1540.
Walker, Lauren E ORCID: 0000-0002-3827-4387, FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin et al (show 23 more authors)
(2022)
An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 111 (3).
pp. 585-594.
Khoo, Saye H ORCID: 0000-0002-2769-0967, Fitzgerald, Richard, Fletcher, Thomas, Ewings, Sean, Jaki, Thomas, Lyon, Rebecca, Downs, Nichola, Walker, Lauren ORCID: 0000-0002-3827-4387, Tansley-Hancock, Olana, Greenhalf, William et al (show 28 more authors)
(2021)
Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76 (12).
pp. 3286-3295.
Kendrick, Tony, Moore, Michael, Leydon, Geraldine M, Stuart, Beth, Geraghty, Adam WA, Yao, Guiqing, Lewis, Glyn, Griffiths, Gareth, May, Carl, Dewar-Haggart, Rachel et al (show 3 more authors)
(2020)
Patient-reported outcome measures for monitoring primary care patients with depression (PROMDEP): study protocol for a randomised controlled trial.
TRIALS, 21 (1).
441-.
FitzGerald, Richard, Dickinson, Laura ORCID: 0000-0001-5557-9396, Else, Laura, Fletcher, Thomas, Hale, Colin, Amara, Alieu ORCID: 0000-0002-1137-2948, Walker, Lauren ORCID: 0000-0002-3827-4387, Penchala, Sujan Dilly, Lyon, Rebecca, Shaw, Victoria ORCID: 0000-0002-0429-0186 et al (show 9 more authors)
(2022)
Pharmacokinetics of ss-d-N4-Hydroxycytidine, the Parent Nucleoside of Prodrug Molnupiravir, in Nonplasma Compartments of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
CLINICAL INFECTIOUS DISEASES, 75 (1).
E525-E528.
Kendrick, Tony, Geraghty, Adam WA, Bowers, Hannah, Stuart, Beth, Leydon, Geraldine, May, Carl, Yao, Guiqing, O'Brien, Wendy, Glowacka, Marta, Holley, Simone et al (show 15 more authors)
(2020)
REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: protocol for a randomised controlled trial.
TRIALS, 21 (1).
419-.