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Chan, Wai Kit ORCID: 0000-0002-8097-0802, Howe, Katherine, Clegg, James M, Guimond, Scott E ORCID: 0000-0002-5903-418X, Price, David J ORCID: 0000-0002-5318-307X, Turnbull, Jeremy E ORCID: 0000-0002-1791-754X and Pratt, Thomas ORCID: 0000-0002-7105-3527
(2015)
2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.
PloS one, 10 (6).
e0130147-.
Duckworth, Carrie A ORCID: 0000-0001-9992-7540, Guimond, Scott E, Sindrewicz, Paulina, Hughes, Ashley J ORCID: 0000-0001-5432-5271, French, Neil S ORCID: 0000-0002-9376-3482, Lian, Lu-Yun, Yates, Edwin A ORCID: 0000-0001-9365-5433, Pritchard, D Mark ORCID: 0000-0001-7971-3561, Rhodes, Jonathan M ORCID: 0000-0002-1302-260X, Turnbull, Jeremy E ORCID: 0000-0002-1791-754X et al (show 1 more authors)
(2015)
Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis.
ONCOTARGET, 6 (27).
pp. 23671-23687.
Zubkova, Olga V, Ahmed, Yassir A, Guimond, Scott E, Noble, Sophia-Louise, Miller, John Holmes, Smith, Raymond Alexander Alfred, Nurcombe, Victor, Tyler, Peter C, Weissmann, Marina, Vlodavsky, Israel et al (show 1 more authors)
(2018)
Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy.
ACS Chemical Biology, 13 (12).
pp. 3236-3242.
Xu, Ruoyan, Ori, Alessandro, Rudd, Timothy R ORCID: 0000-0003-4434-0333, Uniewicz, Katarzyna A, Ahmed, Yassir A, Guimond, Scott E, Skidmore, Mark A, Siligardi, Giuliano, Yates, Edwin A ORCID: 0000-0001-9365-5433 and Fernig, David G ORCID: 0000-0003-4875-4293
(2012)
Diversification of the Structural Determinants of Fibroblast Growth Factor-Heparin Interactions <i>IMPLICATIONS FOR BINDING SPECIFICITY</i>.
JOURNAL OF BIOLOGICAL CHEMISTRY, 287 (47).
pp. 40061-40073.
Mycroft-West, Courtney J, Cooper, Lynsay C, Devlin, Anthony J, Procter, Patricia, Guimond, Scott E, Guerrini, Marco, Fernig, David G ORCID: 0000-0003-4875-4293, Lima, Marcelo A, Yates, Edwin A ORCID: 0000-0001-9365-5433 and Skidmore, Mark A
(2019)
A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease.
MARINE DRUGS, 17 (5).
E293-.
Mycroft-West, Courtney J, Devlin, Anthony J, Cooper, Lynsay C, Guimond, Scott E, Procter, Patricia, Guerrini, Marco, Miller, Gavin J, Fernig, David G ORCID: 0000-0003-4875-4293, Yates, Edwin A ORCID: 0000-0001-9365-5433, Lima, Marcelo A et al (show 1 more authors)
(2021)
Glycosaminoglycans from <i>Litopenaeus vannamei</i> Inhibit the Alzheimer's Disease β Secretase, BACE1.
MARINE DRUGS, 19 (4).
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Chanalaris, Anastasios, Clarke, Hannah, Guimond, Scott E, Vincent, Tonia L, Turnbull, Jeremy E ORCID: 0000-0002-1791-754X and Troeberg, Linda
(2019)
Heparan Sulfate Proteoglycan Synthesis Is Dysregulated in Human Osteoarthritic Cartilage.
The American journal of pathology, 189 (3).
pp. 632-647.
Maciej-Hulme, Marissa L, Leprince, Anaelle CN, Lavin, Andre, Guimond, Scott E, Turnbull, Jeremy E ORCID: 0000-0002-1791-754X, Pelletier, Julien, Yates, Edwin A ORCID: 0000-0001-9365-5433, Powell, Andrew K and Skidmore, Mark A
(2023)
High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts.
ANALYTICAL METHODS, 15 (11).
pp. 1461-1469.
Mycroft-West, Courtney J, Devlin, Anthony J, Cooper, Lynsay C, Procter, Patricia, Miller, Gavin J, Fernig, David G ORCID: 0000-0003-4875-4293, Guerrini, Marco, Guimond, Scott E, Lima, Marcelo A, Yates, Edwin A ORCID: 0000-0001-9365-5433 et al (show 1 more authors)
(2019)
Inhibition of BACE1, the beta-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus.
NEURAL REGENERATION RESEARCH, 15 (8).
pp. 1546-1553.
Miller, Rebecca L, Guimond, Scott E, Schwörer, Ralf, Zubkova, Olga V, Tyler, Peter C, Xu, Yongmei, Liu, Jian, Chopra, Pradeep, Boons, Geert-Jan, Grabarics, Márkó et al (show 6 more authors)
(2020)
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides.
Nature communications, 11 (1).
1481-.
Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M ORCID: 0000-0002-8304-9824, Guimond, Scott E ORCID: 0000-0002-5903-418X, Eyckerman-Kölln, Pieter J, Ten Dam, Gerdy, van Kuppevelt, Toin H, Turnbull, Jeremy E ORCID: 0000-0002-1791-754X and Dierks, Thomas
(2015)
Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.
PloS one, 10 (10).
e0139853-.
Guimond, Scott E, Mycroft-West, Courtney J, Gandhi, Neha S, Tree, Julia A, Le, Thuy T, Spalluto, C Mirella, Humbert, Maria V, Buttigieg, Karen R, Coombes, Naomi, Elmore, Michael J et al (show 32 more authors)
(2022)
Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction.
ACS Central Science, 8 (5).
pp. 527-545.
Miller, Rebecca L, Guimond, Scott E, Prescott, Mark, Turnbull, Jeremy E ORCID: 0000-0002-1791-754X and Karlsson, Niclas
(2017)
Versatile Separation and Analysis of Heparan Sulfate Oligosaccharides Using Graphitized Carbon Liquid Chromatography and Electrospray Mass Spectrometry.
ANALYTICAL CHEMISTRY, 89 (17).
pp. 8942-8950.
Skidmore, Mark A, Mustaffa, Khairul Mohd Fadzli, Cooper, Lynsay C, Guimond, Scott E, Yates, Edwin A ORCID: 0000-0001-9365-5433 and Craig, Alister G ORCID: 0000-0003-0914-6164
(2017)
A semi-synthetic glycosaminoglycan analogue inhibits and reverses <i>Plasmodium falciparum</i> cytoadherence.
PLOS ONE, 12 (10).
e0186276-.