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Petraitis, Vidmantas, Petraitiene, Ruta, Valdez, Jessica M, Pyrgos, Vasilios, Lizak, Martin J, Klaunberg, Brenda A, Kalasauskas, Darius, Basevicius, Algidas, Bacher, John D, Benjamin, Daniel K Jr et al (show 2 more authors)
(2019)
Amphotericin B Penetrates into the Central Nervous System through Focal Disruption of the Blood-Brain Barrier in Experimental Hematogenous <i>Candida</i> Meningoencephalitis.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63 (12).
AAC.01626-AAC.01619.
Petraitis, Vidmantas, Petraitiene, Ruta, McCarthy, Matthew W, Kovanda, Laura L 
ORCID: 0000-0002-4493-4652, Zaw, Myo H, Hussain, Kaiser, Shaikh, Naima, Maung, Bo Bo W, Sekhon, Navjot K, Hope, William W ORCID: 0000-0001-6187-878X et al (show 1 more authors)
(2017)
Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (9).
e00305-e00317.
Boyd, Sara E ORCID: 0000-0001-9935-5263, Moore, Luke SP, Rawson, Timothy M ORCID: 0000-0002-2630-9722, Hope, William W ORCID: 0000-0001-6187-878X and Holmes, Alison H ORCID: 0000-0001-5554-5743
(2017)
Combination therapy for carbapenemase-producing Enterobacteriaceae: INCREMENT-al effect on resistance remains unclear.
LANCET INFECTIOUS DISEASES, 17 (9).
899-+.
Rodvold, Keith A, Hope, William W ORCID: 0000-0001-6187-878X and Boyd, Sara E ORCID: 0000-0001-9935-5263
(2017)
Considerations for effect site pharmacokinetics to estimate drug exposure: concentrations of antibiotics in the lung.
CURRENT OPINION IN PHARMACOLOGY, 36.
pp. 114-123.
Kovanda, Laura L ORCID: 0000-0002-4493-4652, Sass, Gabriele, Martinez, Marife, Clemons, Karl V, Nazik, Hasan, Kitt, Therese M, Wiederhold, Nathan ORCID: 0000-0002-2225-5122, Hope, William W ORCID: 0000-0001-6187-878X and Stevens, David A
(2021)
Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis.
Antimicrobial agents and chemotherapy, 65 (6).
e02344-e02320.
Rawson, Timothy M ORCID: 0000-0002-2630-9722, Wilson, Richard C ORCID: 0000-0002-3275-6932, Moore, Luke SP, Macgowan, Alasdair P, Lovering, Andrew M, Bayliss, Mark, Kyriakides, Mathew, Gilchrist, Mark, Roberts, Jason A, Hope, William W ORCID: 0000-0001-6187-878X et al (show 1 more authors)
(2021)
Exploring the Pharmacokinetics of Phenoxymethylpenicillin (Penicillin-V) in Adults: A Healthy Volunteer Study.
OPEN FORUM INFECTIOUS DISEASES, 8 (12).
ofab573-.
Kovanda, Laura L, Walsh, Thomas J, Benjamin, Daniel K Jr, Arrieta, Antonio, Kaufman, David A, Smith, P Brian, Manzoni, Paolo, Desai, Amit V, Kaibara, Atsunori, Bonate, Peter L et al (show 1 more authors)
(2018)
Exposure-Response Analysis of Micafungin in Neonatal Candidiasis: Pooled Analysis of Two Clinical Trials.
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 37 (6).
pp. 580-585.
Desai, Amit V, Kovanda, Laura L ORCID: 0000-0002-4493-4652, Hope, William W ORCID: 0000-0001-6187-878X, Andes, David, Mouton, Johan W, Kowalski, Donna L, Townsend, Robert W, Mujais, Salim and Bonate, Peter L
(2017)
Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (12).
e01034-e01017.
Bulitta, Jurgen B, Hope, William W ORCID: 0000-0001-6187-878X, Eakin, Ann E, Guina, Tina, Tam, Vincent H, Louie, Arnold, Drusano, George L and Hoover, Jennifer L
(2019)
Generating Robust and Informative Nonclinical <i>In Vitro</i> and <i>In Vivo</i> Bacterial Infection Model Efficacy Data To Support Translation to Humans.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63 (5).
e02307-e02318.
Kovanda, Laura L ORCID: 0000-0002-4493-4652, Marty, Francisco M, Maertens, Johan, Desai, Amit V, Lademacher, Christopher, Engelhardt, Marc, Lu, Qiaoyang and Hope, William W ORCID: 0000-0001-6187-878X
(2017)
Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (6).
e00101-e00117.
Kovanda, Laura L ORCID: 0000-0002-4493-4652, Desai, Amit V, Lu, Qiaoyang, Townsend, Robert W, Akhtar, Shahzad, Bonate, Peter and Hope, William W ORCID: 0000-0001-6187-878X
(2016)
Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study).
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 60 (8).
pp. 4568-4576.
Boyd, Sara E ORCID: 0000-0001-9935-5263, Livermore, David M, Hooper, David C and Hope, William W ORCID: 0000-0001-6187-878X
(2020)
Metallo-β-Lactamases: Structure, Function, Epidemiology, Treatment Options, and the Development Pipeline.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 64 (10).
e00397-e00320.
Andes, David R, Ghannoum, Mahmoud A, Mukherjee, Pranab K, Kovanda, Laura L ORCID: 0000-0002-4493-4652, Lu, Qiaoyang, Jones, Mark E, Henriksen, Anne Santerre, Lademacher, Christopher and Hope, William W ORCID: 0000-0001-6187-878X
(2019)
Outcomes by MIC Values for Patients Treated with Isavuconazole or Voriconazole for Invasive Aspergillosis in the Phase 3 SECURE and VITAL Trials.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63 (1).
e01634-e01618.
Sime, Fekade Bruck, Johnson, Adam ORCID: 0000-0002-6684-3321, Whalley, Sarah, Santoyo-Castelazo, Anahi, Montgomery, A Bruce, Walters, Kathie Ann, Lipman, Jeffrey, Hope, William W ORCID: 0000-0001-6187-878X and Roberts, Jason A
(2017)
Pharmacodynamics of Aerosolized Fosfomycin and Amikacin against Resistant Clinical Isolates of <i>Pseudomonas aeruginosa</i> and <i>Klebsiella pneumoniae</i> in a Hollow-Fiber Infection Model: Experimental Basis for Combination Therapy.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (1).
e01763-e01716.
Kovanda, Laura L ORCID: 0000-0002-4493-4652, Giamberardino, Charles, McEntee, Laura, Toffaletti, Dena L, Franke, Kelly S, Bartuska, Andrew, Smilnak, Gordon, de Castro, George C, Ripple, Katelyn, Hope, William W ORCID: 0000-0001-6187-878X et al (show 1 more authors)
(2019)
Pharmacodynamics of Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63 (9).
e00546-e00519.
Kovanda, Laura L ORCID: 0000-0002-4493-4652, Petraitiene, Ruta, Petraitis, Vidmantas, Walsh, Thomas J, Desai, Amit, Bonate, Peter and Hope, William W ORCID: 0000-0001-6187-878X
(2016)
Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71 (7).
pp. 1885-1891.
Benjamin, Daniel K Jr, Kaufman, David A, Hope, William W ORCID: 0000-0001-6187-878X, Smith, P Brian, Arrieta, Antonio, Manzoni, Paolo, Kovanda, Laura L, Lademacher, Christopher, Isaacson, Brigit, Jednachowski, Deborah et al (show 3 more authors)
(2018)
A Phase 3 Study of Micafungin Versus Amphotericin B Deoxycholate in Infants With Invasive Candidiasis.
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 37 (10).
pp. 992-998.
Kovanda, Laura L ORCID: 0000-0002-4493-4652, Sullivan, Sean M, Smith, Larry R, Desai, Amit V, Bonate, Pete L and Hope, William W ORCID: 0000-0001-6187-878X
(2019)
Population Pharmacokinetic Modeling of VL-2397, A Novel Systemic Antifungal Agent: Analysis of a Single and Multiple Ascending Dose Study in Healthy Subjects.
Antimicrobial agents and chemotherapy, 63 (6).
e00163-e00119.
Bustinduy, Amaya L, Waterhouse, David, de Sousa-Figueiredo, Jose C, Roberts, Stephen A, Atuhaire, Aaron, Van Dam, Govert J, Corstjens, Paul LAM, Scott, Janet T ORCID: 0000-0001-8030-5223, Stanton, Michelle C, Kabatereine, Narcis B et al (show 3 more authors)
(2016)
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy.
mBio, 7 (4).
e00227-e00216.
Lestner, Jodi M, Groll, Andreas H, Aljayyoussi, Ghaith, Seibel, Nita L, Shad, Aziza, Gonzalez, Corina, Wood, Lauren V, Jarosinski, Paul F, Walsh, Thomas J and Hope, William W ORCID: 0000-0001-6187-878X
(2016)
Population Pharmacokinetics of Liposomal Amphotericin B in Immunocompromised Children.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 60 (12).
pp. 7340-7346.
Merino-Bohorquez, Vicente, Docobo-Perez, Fernando, Valiente-Mendez, Adoracion, Delgado-Valverde, Mercedes, Camean, Manuel, Hope, William W ORCID: 0000-0001-6187-878X, Pascual, Alvaro and Rodriguez-Bano, Jesus
(2021)
Population Pharmacokinetics of Piperacillin in Non-Critically Ill Patients with Bacteremia Caused by Enterobacteriaceae.
ANTIBIOTICS-BASEL, 10 (4).
348-.
Bustinduy, Amaya L, Kolamunnage-Dona, Ruwanthi ORCID: 0000-0003-3886-6208, Mirochnick, Mark H, Capparelli, Edmund V, Tallo, Veronica, Acosta, Luz P, Olveda, Remigio M, Friedman, Jennifer F and Hope, William W ORCID: 0000-0001-6187-878X
(2020)
Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum.
Antimicrobial Agents and Chemotherapy, 64 (9).
e00566-e00520.
Kovanda, Laura L ORCID: 0000-0002-4493-4652, Desai, Amit V and Hope, William W ORCID: 0000-0001-6187-878X
(2017)
Prognostic value of galactomannan: current evidence for monitoring response to antifungal therapy in patients with invasive aspergillosis.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 44 (2).
pp. 143-151.
Stott, Katharine E ORCID: 0000-0001-7079-7957 and Hope, William W ORCID: 0000-0001-6187-878X
(2017)
Therapeutic drug monitoring for invasive mould infections and disease: pharmacokinetic and pharmacodynamic considerations.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 72 (suppl_).
I12-I18.
Schmitt-Hoffmann, Anne-Hortense, Kato, Kota, Townsend, Robert, Potchoiba, Michael J, Hope, William W ORCID: 0000-0001-6187-878X, Andes, David, Spickermann, Jochen and Schneidkraut, Marlowe J
(2017)
Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (12).
e01292-e01217.
Hope, William W ORCID: 0000-0001-6187-878X, Walsh, Thomas J, Goodwin, Joanne, Peloquin, Charles A, Howard, Alan, Kurtzberg, Joanne, Mendizabal, Alan, Confer, Dennis L, Bulitta, Jurgen, Baden, Lindsey R et al (show 2 more authors)
(2016)
Voriconazole pharmacokinetics following HSCT: results from the BMT CTN 0101 trial.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71 (8).
pp. 2234-2240.
Webb, Emily L, Edielu, Andrew, Wu, Hannah W, Kabatereine, Narcis B, Tukahebwa, Edridah M, Mubangizi, Alfred, Adriko, Moses, Elliott, Alison M, Hope, William W ORCID: 0000-0001-6187-878X, Mawa, Patrice A et al (show 2 more authors)
(2021)
The praziquantel in preschoolers (PIP) trial: study protocol for a phase II PK/PD-driven randomised controlled trial of praziquantel in children under 4 years of age.
TRIALS, 22 (1).
601-.