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Ranganath, Lakshminarayan R ORCID: 0000-0002-4205-2269, Milan, Anna M, Hughes, Andrew T, Khedr, Milad, Norman, Brendan P ORCID: 0000-0001-9293-4852, Alsbou, Mohammed, Imrich, Richard, Gornall, Matthew, Sireau, Nicolas, Gallagher, James A ORCID: 0000-0002-0852-279X
et al (show 1 more authors) (2022) Comparing nitisinone 2 mg and 10 mg in the treatment of alkaptonuria-An approach using statistical modelling. JIMD reports, 63 (1). pp. 80-92.


Ranganath, Lakshminarayan R, Milan, Anna M, Hughes, Andrew T, Davison, Andrew S ORCID: 0000-0001-5501-4475, Khedr, Milad, Imrich, Richard, Rudebeck, Mattias, Olsson, Birgitta, Norman, Brendan P ORCID: 0000-0001-9293-4852, Bou-Gharios, George
et al (show 1 more authors) (2022) Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment. METABOLITES, 12 (8). 772-.


Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hickton, Bryony, Ross, Gordon A, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Wilson, Peter JM, Sutherland, Hazel, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Roberts, Norman B
et al (show 3 more authors) (2022) Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria. METABOLITES, 12 (10). 927-.


Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Ross, Gordon A, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Sutherland, Hazel, Jarvis, Jonathan C, Roberts, Norman B, Gallagher, James A ORCID: 0000-0002-0852-279X and Ranganath, Lakshminarayan R
(2019) A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria. Clinical chemistry, 65 (4). pp. 530-539.


Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P ORCID: 0000-0001-9293-4852, Hughes, Andrew T, Keenan, Craig M ORCID: 0000-0002-8782-8016, Milan, Anna M ORCID: 0000-0002-0452-2338, Sakai, Takao ORCID: 0000-0002-7375-5450
et al (show 3 more authors) (2019) Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria. Human Molecular Genetics, 28 (23). pp. 3928-3939.


Hughes, Juliette H ORCID: 0000-0001-6155-4136, Liu, Ke, Plagge, Antonius ORCID: 0000-0001-6592-1343, Wilson, Peter JM, Sutherland, Hazel, Norman, Brendan P, Hughes, Andrew T, Keenan, Craig M, Milan, Anna M, Sakai, Takao ORCID: 0000-0002-7375-5450
et al (show 3 more authors) (2019) Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria. Human molecular genetics.


Hughes, Juliette H ORCID: 0000-0001-6155-4136, Wilson, Peter JM, Sutherland, Hazel, Judd, Shirley, Hughes, Andrew T, Milan, Anna M ORCID: 0000-0002-0452-2338, Jarvis, Jonathan C, Bou-Gharios, George, Ranganath, Lakshminarayan R and Gallagher, James A
(2020) Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43 (2). pp. 259-268.


Ranganath, Lakshminarayan R, Psarelli, Eftychia Eirini ORCID: 0000-0002-3102-0288, Arnoux, Jean-Baptiste, Braconi, Daniela, Briggs, Michael, Broijersen, Anders, Loftus, Nadia, Bygott, Helen, Cox, Trevor F, Davison, Andrew S ORCID: 0000-0001-5501-4475
et al (show 39 more authors) (2020) Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial. The Lancet Diabetes and Endocrinology, 8 (9). pp. 762-772.


Davison, Andrew S ORCID: 0000-0001-5501-4475, Norman, Brendan P ORCID: 0000-0001-9293-4852, Ross, Gordon A, Hughes, Andrew T, Khedr, Milad ORCID: 0000-0002-4998-2397, Milan, Anna M ORCID: 0000-0002-0452-2338, Gallagher, James A and Ranganath, Lakshminarayan R
(2019) Evaluation of the serum metabolome of patients with alkaptonuria before and after two years of treatment with nitisinone using LC-QTOF-MS. JIMD reports, 48 (1). pp. 67-74.


Ranganath, Lakshminarayan R, Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Khedr, Milad ORCID: 0000-0002-4998-2397, Davison, Andrew S ORCID: 0000-0001-5501-4475, Shweihdi, Ella, Norman, Brendan P ORCID: 0000-0001-9293-4852, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Bygott, Helen, Luangrath, Emily
et al (show 20 more authors) (2020) Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43 (4). pp. 737-747.


Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Sutherland, Hazel, Wilson, Peter JM, Berry, Neil G ORCID: 0000-0003-1928-0738, Hughes, Andrew T, Milan, Anna M, Jarvis, Jonathan C, Roberts, Norman B
et al (show 3 more authors) (2022) Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism. GENES & DISEASES, 9 (4). pp. 1129-1142.


Hughes, Andrew T, Milan, Anna M ORCID: 0000-0002-0452-2338, Shweihdi, Ella, Gallagher, James ORCID: 0000-0002-0852-279X and Ranganath, Lakshminarayan
(2022) Method development and validation for analysis of phenylalanine, 4‐hydroxyphenyllactic acid and 4‐hydroxyphenylpyruvic acid in serum and urine. JIMD Reports, 63 (4). pp. 341-350.


Khedr, Milad ORCID: 0000-0002-4998-2397, Cooper, Maggie S, Hughes, Andrew T, Milan, Anna M ORCID: 0000-0002-0452-2338, Davison, Andrew S ORCID: 0000-0001-5501-4475, Norman, Brendan P ORCID: 0000-0001-9293-4852, Sutherland, Hazel, Jarvis, Jonathan C, Fitzgerald, Richard, Markinson, Louise
et al (show 5 more authors) (2020) Nitisinone causes acquired tyrosinosis in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43 (5). pp. 1014-1023.


Ranganath, Lakshminarayan R ORCID: 0000-0002-4205-2269, Milan, Anna M, Hughes, Andrew T, Khedr, Milad, Davison, Andrew S ORCID: 0000-0001-5501-4475, Wilson, Peter J, Dillon, Jane P ORCID: 0000-0002-7055-5664, West, Elizabeth and Gallagher, James A
(2020) Reversal of ochronotic pigmentation in alkaptonuria following nitisinone therapy: Analysis of data from the United Kingdom National Alkaptonuria Centre. JIMD reports, 55 (1). pp. 75-87.


Ranganath, Lakshminarayan R, Hughes, Andrew T, Davison, Andrew S ORCID: 0000-0001-5501-4475, Khedr, Milad, Imrich, Richard, Rudebeck, Mattias, Olsson, Birgitta, Norman, Brendan P ORCID: 0000-0001-9293-4852, Bou-Gharios, George, Gallagher, James A
et al (show 1 more authors) (2022) Revisiting Quantification of Phenylalanine/Tyrosine Flux in the Ochronotic Pathway during Long-Term Nitisinone Treatment of Alkaptonuria. METABOLITES, 12 (10). 920-.


Norman, Brendan P ORCID: 0000-0001-9293-4852, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Juliette H ORCID: 0000-0001-6155-4136, Sutherland, Hazel, Wilson, Peter J, Berry, Neil G, Hughes, Andrew T, Milan, Anna M, Jarvis, Jonathan C, Roberts, Norman B
et al (show 3 more authors) (2020) Studies in alkaptonuria reveal new roles beyond drug clearance for phase I and II biotransformations in tyrosine metabolism. biorxiv. (Unpublished)


Milan, Anna M ORCID: 0000-0002-0452-2338, Hughes, Andrew T, Davison, Andrew S ORCID: 0000-0001-5501-4475, Devine, Jean, Usher, Jeannette, Curtis, Sarah, Khedr, Milad ORCID: 0000-0002-4998-2397, Gallagher, James A ORCID: 0000-0002-0852-279X and Ranganath, Lakshminarayan R
(2017) The effect of nitisinone on homogentisic acid and tyrosine: a two-year survey of patients attending the National Alkaptonuria Centre, Liverpool. Annals of Clinical Biochemistry, 54 (3). pp. 323-330.


Judd, Shirley ORCID: 0000-0001-9792-0046, Khedr, Milad, Milan, Anna M ORCID: 0000-0002-0452-2338, Davison, Andrew S ORCID: 0000-0001-5501-4475, Hughes, Andrew T, Needham, Alexander, Psarelli, Eftychia E ORCID: 0000-0002-3102-0288, Shenkin, Alan and Ranganath, Lakshiminaryan R
(2020) The nutritional status of people with alkaptonuria: An exploratory analysis suggests a protein/energy dilemma. JIMD reports, 53 (1). pp. 45-60.

This list was generated on Sat Jan 13 05:19:11 2024 GMT.