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Hong, W David, Benayoud, Farid, Nixon, Gemma L, Ford, Louise, Johnston, Kelly L, Clare, Rachel H, Cassidy, Andrew, Cook, Darren AN, Siu, Amy, Shiotani, Motohiro et al (show 24 more authors)
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AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
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Albendazole and antibiotics synergize to deliver short-course anti-<i>Wolbachia</i> curative treatments in preclinical models of filariasis.
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Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library.
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Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides.
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Short-Course, High-Dose Rifampicin Achieves <i>Wolbachia</i> Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.
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<i>Wolbachia</i> depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment.
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