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Gray, Anna L, Karlsson, Richard, Roberts, Abigail RE, Ridley, Amanda JL, Pun, Nabina, Khan, Bakhtbilland, Lawless, Craig, Luis, Rafael, Szpakowska, Martyna, Chevigne, Andy et al (show 14 more authors)
(2023)
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors.
CELL REPORTS, 42 (1).
111930-.
Karlsson, Richard, Chopra, Pradeep, Joshi, Apoorva, Yang, Zhang, Vakhrushev, Sergey Y, Clausen, Thomas Mandel, Painter, Chelsea D, Szekeres, Gergo P, Chen, Yen-Hsi, Sandoval, Daniel R et al (show 8 more authors)
(2021)
Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates.
SCIENCE ADVANCES, 7 (52).
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Schuurs, Zachariah P, Hammond, Edward, Elli, Stefano, Rudd, Timothy R ORCID: 0000-0003-4434-0333, Mycroft-West, Courtney J, Lima, Marcelo A, Skidmore, Mark A, Karlsson, Richard, Chen, Yen-Hsi, Bagdonaite, Ieva et al (show 7 more authors)
(2021)
Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 19.
pp. 2806-2818.
Guimond, Scott E, Mycroft-West, Courtney J, Gandhi, Neha S, Tree, Julia A, Le, Thuy T, Spalluto, C Mirella, Humbert, Maria V, Buttigieg, Karen R, Coombes, Naomi, Elmore, Michael J et al (show 32 more authors)
(2022)
Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction.
ACS Central Science, 8 (5).
pp. 527-545.
Tree, Julia A, Turnbull, Jeremy E ORCID: 0000-0002-1791-754X, Buttigieg, Karen R, Elmore, Michael J, Coombes, Naomi, Hogwood, John, Mycroft-West, Courtney J, Lima, Marcelo A, Skidmore, Mark A, Karlsson, Richard et al (show 10 more authors)
(2021)
Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
BRITISH JOURNAL OF PHARMACOLOGY, 178 (3).
pp. 626-635.