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Curley, Paul ORCID: 0000-0003-4596-2708, Liptrott, Neill J ORCID: 0000-0002-5980-8966 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2018)
Advances in nanomedicine drug delivery applications for HIV therapy.
FUTURE SCIENCE OA, 4 (1).
FSO230-.
Sposito, Francesca ORCID: 0009-0007-0272-0318, Pennington, Shaun H, A W David, Christopher, Duggan, Jack, Northey, Sarah, Biagini, Giancarlo, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Charras, Amandine ORCID: 0000-0001-6760-5459, McNamara, Paul S ORCID: 0000-0002-7055-6034 and Hedrich, Christian M ORCID: 0000-0002-1295-6179
(2023)
Age differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - effects of vitamin D.
Mucosal immunology, 16 (6).
S1933-0219(23)00064-8-S1933-0219(23)00064-8.
David, Christopher AW ORCID: 0000-0001-8504-2354, del Castillo Busto, M Estela, Cuello-Nunez, Susana, Goenaga-Infante, Heidi, Barrow, Michael, Fernig, David G ORCID: 0000-0003-4875-4293, Murray, Patricia, Rosseinsky, Matthew J ORCID: 0000-0002-1910-2483, Owen, Andrew ORCID: 0000-0002-9819-7651 and Liptrott, Neill J ORCID: 0000-0002-5980-8966
(2021)
Assessment of changes in autophagic vesicles in human immune cell lines exposed to nano particles.
CELL AND BIOSCIENCE, 11 (1).
133-.
Liptrott, Neill J ORCID: 0000-0002-5980-8966, Giardiello, Marco ORCID: 0000-0003-0560-4711, McDonald, Tom O ORCID: 0000-0002-9273-9173, Rannard, Steve P ORCID: 0000-0002-6946-1097 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2018)
Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems.
JOURNAL OF NANOBIOTECHNOLOGY, 16 (1).
22-.
Arshad, Usman ORCID: 0000-0003-1586-1885, Sutton, Paul A, Ashford, Marianne B, Treacher, Kevin E, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Rannard, Steve P ORCID: 0000-0002-6946-1097, Goldring, Christopher E and Owen, Andrew ORCID: 0000-0002-9819-7651
(2020)
Critical considerations for targeting colorectal liver metastases with nanotechnology.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 12 (2).
e1588-.
Chan, Christina YS, Roberts, Owain, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Siccardi, Marco ORCID: 0000-0002-3539-7867, Almond, Lisa and Owen, Andrew ORCID: 0000-0002-9819-7651
(2018)
Derivation of CYP3A4 and CYP2B6 degradation rate constants in primary human hepatocytes: A siRNA-silencing-based approach.
DRUG METABOLISM AND PHARMACOKINETICS, 33 (4).
pp. 179-187.
Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Pertinez, Henry, Arshad, Usman ORCID: 0000-0003-1586-1885, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony et al (show 13 more authors)
(2021)
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87 (4).
pp. 2078-2088.
Rajoli, Rajith Kr ORCID: 0000-0002-6015-5712, Pertinez, Henry, Arshad, Usman ORCID: 0000-0003-1586-1885, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony et al (show 13 more authors)
(2020)
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
medRxiv : the preprint server for health sciences.
Brain, Danielle ORCID: 0000-0002-1671-8477, Plant-Hately, Alex ORCID: 0000-0003-2425-1990, Heaton, Bethany ORCID: 0000-0002-1495-1945, Arshad, Usman ORCID: 0000-0003-1586-1885, David, Christopher ORCID: 0000-0001-8504-2354, Hedrich, Christian ORCID: 0000-0002-1295-6179, Owen, Andrew ORCID: 0000-0002-9819-7651 and Liptrott, Neill J ORCID: 0000-0002-5980-8966
(2021)
Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19.
ADVANCED DRUG DELIVERY REVIEWS, 178.
113848-.
Curley, Paul ORCID: 0000-0003-4596-2708, Rajoli, Rajith KR ORCID: 0000-0002-6015-5712, Moss, Darren M, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Letendre, Scott, Owen, Andrew ORCID: 0000-0002-9819-7651 and Siccardi, Marco ORCID: 0000-0002-3539-7867
(2017)
Efavirenz Is Predicted To Accumulate in Brain Tissue: an <i>In Silico</i>, <i>In Vitro</i>, and <i>In Vivo</i> Investigation.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61 (1).
e01841-e01816.
Heaton, Bethany J ORCID: 0000-0002-1495-1945, Jensen, Rebecca L ORCID: 0000-0003-1134-2869, Line, James ORCID: 0000-0003-3568-8928, David, Christopher AW ORCID: 0000-0001-8504-2354, Brain, Danielle E ORCID: 0000-0002-1671-8477, Chadwick, Amy E ORCID: 0000-0002-7399-8655 and Liptrott, Neill J ORCID: 0000-0002-5980-8966
(2022)
Exposure of human immune cells, to the antiretrovirals efavirenz and lopinavir, leads to lower glucose uptake and altered bioenergetic cell profiles through interactions with SLC2A1.
BIOMEDICINE & PHARMACOTHERAPY, 150.
112999-.
Plant-Hately, Alexander J, Eryilmaz, Burcu, David, Christopher AW ORCID: 0000-0001-8504-2354, Brain, Danielle E ORCID: 0000-0002-1671-8477, Heaton, Bethany J ORCID: 0000-0002-1495-1945, Perrie, Yvonne and Liptrott, Neill J ORCID: 0000-0002-5980-8966
(2022)
Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics.
PHARMACEUTICS, 14 (11).
2470-.
Amadeo, Francesco ORCID: 0000-0002-3868-2348, Hanson, Vivien, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Wilm, Bettina ORCID: 0000-0002-9245-993X, Murray, Patricia and Taylor, Arthur ORCID: 0000-0003-2028-6694
(2023)
Fate of intravenously administered umbilical cord mesenchymal stromal cells and interactions with the host's immune system.
BIOMEDICINE & PHARMACOTHERAPY, 159.
114191-.
Hannon, Gary, Lysaght, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966 and Prina-Mello, Adriele
(2019)
Immunotoxicity Considerations for Next Generation Cancer Nanomedicines.
ADVANCED SCIENCE, 6 (19).
1900133-.
David, Christopher AW ORCID: 0000-0001-8504-2354, Barrow, Michael, Murray, Patricia, Rosseinsky, Matthew J ORCID: 0000-0002-1910-2483, Owen, Andrew ORCID: 0000-0002-9819-7651 and Liptrott, Neill J ORCID: 0000-0002-5980-8966
(2020)
In Vitro Determination of the Immunogenic Impact of Nanomaterials on Primary Peripheral Blood Mononuclear Cells.
International Journal of Molecular Sciences, 21 (16).
p. 5610.
Curley, Paul ORCID: 0000-0003-4596-2708, Giardiello, Marco ORCID: 0000-0003-0560-4711, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Dickens, David ORCID: 0000-0001-8295-0752, Moss, Darren M, Hobson, James J ORCID: 0000-0003-2551-1774, Savage, Alison C, McDonald, Tom O, Siccardi, Marco, Rannard, Steve et al (show 1 more authors)
(2017)
In vitro characterisation of solid drug nanoparticle compositions of efavirenz in a brain endothelium cell line.
Journal of Interdisciplinary Nanomedicine, 2 (3).
pp. 157-169.
Chan, Christina, Martin, Philip, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Siccardi, Marco ORCID: 0000-0002-3539-7867, Almond, Lisa and Owen, Andrew ORCID: 0000-0002-9819-7651
(2017)
Incompatibility of chemical protein synthesis inhibitors with accurate measurement of extended protein degradation rates.
PHARMACOLOGY RESEARCH & PERSPECTIVES, 5 (5).
e00359-e00359.
Avila, Yelixza I, Chandler, Morgan, Cedrone, Edward, Newton, Hannah S, Richardson, Melina, Xu, Jie, Clogston, Jeffrey D, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Afonin, Kirill A and Dobrovolskaia, Marina A
(2021)
Induction of Cytokines by Nucleic Acid Nanoparticles (NANPs) Depends on the Type of Delivery Carrier.
MOLECULES, 26 (3).
652-.
Hernandez Pichardo, Alejandra ORCID: 0000-0001-7774-4452, Wilm, Bettina ORCID: 0000-0002-9245-993X, Liptrott, Neill J ORCID: 0000-0002-5980-8966 and Murray, Patricia ORCID: 0000-0003-1316-148X
(2023)
Intravenous Administration of Human Umbilical Cord Mesenchymal Stromal Cells Leads to an Inflammatory Response in the Lung.
Stem cells international, 2023.
p. 7397819.
Liptrott, Neill J ORCID: 0000-0002-5980-8966, Giardiello, Marco ORCID: 0000-0003-0560-4711, McDonald, Tom O ORCID: 0000-0002-9273-9173, Rannard, Steven P ORCID: 0000-0002-6946-1097 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2017)
Lack of interaction of lopinavir solid drug nanoparticles with cells of the immune system.
NANOMEDICINE, 12 (17).
pp. 2043-2054.
Tatham, Lee M ORCID: 0000-0001-9448-8876, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Rannard, Steve P ORCID: 0000-0002-6946-1097 and Owen, Andrew ORCID: 0000-0002-9819-7651
(2019)
Long-Acting Injectable Statins-Is It Time for a Paradigm Shift?
MOLECULES, 24 (15).
E2685-.
Urban, Patricia, Liptrott, Neill J ORCID: 0000-0002-5980-8966 and Bremer, Susanne
(2019)
Overview of the blood compatibility of nanomedicines: A trend analysis of in vitro and in vivo studies.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 11 (3).
e1546-.
Curley, Paul, Hobson, James J ORCID: 0000-0003-2551-1774, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Makarov, Edward, Al-Khouja, Amer, Tatham, Lee ORCID: 0000-0001-9448-8876, David, Christopher AW ORCID: 0000-0001-8504-2354, Box, Helen, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne et al (show 7 more authors)
(2023)
Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations.
Pharmaceutics, 15 (7).
p. 1835.
Arshad, Usman ORCID: 0000-0003-1586-1885, Pertinez, Henry, Box, Helen, Tatham, Lee ORCID: 0000-0001-9448-8876, Rajoli, Rajith Kr ORCID: 0000-0002-6015-5712, Curley, Paul ORCID: 0000-0003-4596-2708, Neary, Megan ORCID: 0000-0002-4960-2139, Sharp, Joanne, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Valentijn, Anthony et al (show 12 more authors)
(2020)
Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.
Clinical pharmacology and therapeutics, 108 (4).
pp. 775-790.
Hobson, James J ORCID: 0000-0003-2551-1774, Rannard, Steve P ORCID: 0000-0002-6946-1097, Owen, Andrew ORCID: 0000-0002-9819-7651 and Liptrott, Neill J ORCID: 0000-0002-5980-8966
(2020)
Safety assessment of a new nanoemulsion-based drug-delivery system reveals unexpected, drug-free, anticoagulant activity.
Nanomedicine, 15 (14).
pp. 1361-1374.
Rosslein, Matthias, Liptrott, Neill J ORCID: 0000-0002-5980-8966, Owen, Andrew ORCID: 0000-0002-9819-7651, Boisseau, Patrick, Wick, Peter and Herrmann, Inge K
(2017)
Sound understanding of environmental, health and safety, clinical, and market aspects is imperative to clinical translation of nanomedicines.
NANOTOXICOLOGY, 11 (2).
pp. 147-149.
da Silva, Tamiris Borges, Rendra, Erika, David, Christopher AW ORCID: 0000-0001-8504-2354, Bieback, Karen, Cross, Michael J ORCID: 0000-0002-5533-1232, Wilm, Bettina ORCID: 0000-0002-9245-993X, Liptrott, Neill J ORCID: 0000-0002-5980-8966 and Murray, Patricia ORCID: 0000-0003-1316-148X
(2023)
Umbilical cord mesenchymal stromal cell-derived extracellular vesicles lack the potency to immunomodulate human monocyte-derived macrophages in vitro.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 167.
115624-.
Vandebriel, Rob J, David, Christopher AW ORCID: 0000-0001-8504-2354, Vermeulen, Jolanda P and Liptrott, Neill J ORCID: 0000-0002-5980-8966
(2022)
An inter-laboratory comparison of an NLRP3 inflammasome activation assay and dendritic cell maturation assay using a nanostructured lipid carrier and a polymeric nanomedicine, as exemplars.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 12 (9).
pp. 2225-2242.