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Number of items: 44.


Almutairi, Mubarak, Lister, Adam ORCID: 0000-0003-4085-6367, Zhao, Qing, Line, James ORCID: 0000-0003-3568-8928, Adair, Kareena ORCID: 0000-0001-9884-2094, Tailor, Arun, Waddington, James ORCID: 0000-0003-2641-5055, Clarke, Elsie ORCID: 0000-0002-5913-0606, Gardner, Joshua ORCID: 0000-0002-4520-108X, Thomson, Paul ORCID: 0000-0001-5431-0459
et al (show 10 more authors) (2023) Activation of Human CD8+ T Cells with Nitroso Dapsone-Modified HLA-B*13:01-Binding Peptides. Journal of immunology (Baltimore, Md. : 1950), 210 (8). pp. 1031-1042.


Hammond, Sean, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Mosedale, Merrie and Naisbitt, Dean J
(2023) Activation of tolvaptan-responsive T-cell clones with the structurally-related mozavaptan. Toxicology Letters, 373. pp. 148-151.


Meng, Xiaoli ORCID: 0000-0002-7774-2075, Earnshaw, Caroline J, Tailor, Arun ORCID: 0000-0002-9698-3480, Jenkins, Rosalind E, Waddington, James C ORCID: 0000-0003-2641-5055, Whitaker, Paul, French, Neil S ORCID: 0000-0002-9376-3482, Naisbitt, Dean J and Park, B Kevin ORCID: 0000-0001-8384-824X
(2016) Amoxicillin and Clavulanate Form Chemically and Immunologically Distinct Multiple Haptenic Structures in Patients. CHEMICAL RESEARCH IN TOXICOLOGY, 29 (10). pp. 1762-1772.


Tailor, AA ORCID: 0000-0002-9698-3480
(2018) Analysis of drug-protein adducts and their role in drug hypersensitivity. PhD thesis, University of Liverpool.


Amali, Mohammed O, Jenkins, Rosalind E, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Faulkner, Lee, Whitaker, Paul, Peckham, Daniel, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2017) Assessment of Antipiperacillin IgG Binding to Structurally Related Drug Protein Adducts. CHEMICAL RESEARCH IN TOXICOLOGY, 30 (12). pp. 2097-2099.


Meng, Xiaoli ORCID: 0000-0002-7774-2075, Waddington, James C ORCID: 0000-0003-2641-5055, Tailor, Arun, Lister, Adam, Hamlett, Jane, Berry, Neil ORCID: 0000-0003-1928-0738, Park, B Kevin ORCID: 0000-0001-8384-824X and Sporn, Michael B
(2020) CDDO-imidazolide Targets Multiple Amino Acid Residues on the Nrf2 Adaptor, Keap1. JOURNAL OF MEDICINAL CHEMISTRY, 63 (17). pp. 9965-9976.


Waddington, James C ORCID: 0000-0003-2641-5055, Ali, Serat-E ORCID: 0000-0002-9806-8796, Penman, Sophie L ORCID: 0000-0001-5326-1675, Whitaker, Paul, Hamlett, Jane, Chadwick, Amy ORCID: 0000-0002-7399-8655, Naisbitt, Dean J, Park, B Kevin ORCID: 0000-0001-8384-824X and Meng, Xiaoli ORCID: 0000-0002-7774-2075
(2020) Cell Membrane Transporters Facilitate the Accumulation of Hepatocellular Flucloxacillin Protein Adducts: Implication in Flucloxacillin-Induced Liver Injury. CHEMICAL RESEARCH IN TOXICOLOGY, 33 (12). pp. 2939-2943.


Ogese, Monday O ORCID: 0000-0002-1873-4032, Lister, Adam, Jenkins, Rosalind E, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Alfirevic, Ana ORCID: 0000-0002-2801-9817, Douglas, Lisa, Mcloughlin, Rachel, Silva, Edward, Park, B Kevin ORCID: 0000-0001-8384-824X, Pirmohamed, Munir ORCID: 0000-0002-7534-7266
et al (show 1 more authors) (2020) Characterization of Clozapine-Responsive Human T Cells. JOURNAL OF IMMUNOLOGY, 205 (9). 2375-+.


Alhilali, Khetam Ali, Al-Attar, Zaid, Gibson, Andrew, Tailor, Arun ORCID: 0000-0002-9698-3480, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Monshouwer, Mario, Snoeys, Jan, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2019) Characterization of Healthy Donor-Derived T-Cell Responses Specific to Telaprevir Diastereomers. TOXICOLOGICAL SCIENCES, 168 (2). pp. 597-609.


Usui, Toru, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Saide, Katy, Farrell, John ORCID: 0000-0002-8726-5997, Thomson, Paul ORCID: 0000-0001-5431-0459, Whitaker, Paul, Watson, John, French, Neil S ORCID: 0000-0002-9376-3482, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2017) Characterization of Isoniazid-Specific T-Cell Clones in Patients with anti-Tuberculosis Drug-Related Liver and Skin Injury. TOXICOLOGICAL SCIENCES, 155 (2). pp. 420-431.


Ogese, Monday O ORCID: 0000-0002-1873-4032, Jenkins,, Rosalind E, Maggs, James L, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Whitaker, Paul, Peckham, Daniel, Faulkner, Lee, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2015) Characterization of Peroxidases Expressed in Human AntigenPresenting Cells and Analysis of the Covalent Binding of NitrosoSulfamethoxazole to Myeloperoxidase. Chemical Research in Toxicology, 28 (1). pp. 144-154.


Ariza, Adriana, Fernandez-Santamaria, Ruben, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Salas, Maria, Ogese, Monday O ORCID: 0000-0002-1873-4032, Tailor, Arun, Bogas, Gador, Torres, Maria Jose and Naisbitt, Dean J
(2020) Characterization of amoxicillin and clavulanic acid specific T-cell clones from patients with immediate drug hypersensitivity. ALLERGY, 75 (10). pp. 2562-2573.


Hammond, Sean, Olsson-Brown, Anna, Grice, Sophie, Gibson, Andrew, Gardner, Joshua, Castrejon-Flores, Jose Luis, Jolly, Carol, Fisher, Benjamin Alexis, Steven, Neil, Betts, Catherine
et al (show 3 more authors) (2022) Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity. TOXICOLOGICAL SCIENCES, 186 (1). pp. 58-69.


Ali, Serat-E ORCID: 0000-0002-9806-8796
(2021) DEVELOPMENT OF IN VITRO CELL-BASED SYSTEMS TO INVESTIGATE DRUG IMMUNOGENICITY. PhD thesis, University of Liverpool.


Zhao, Qing, Alhilali, Khetam, Alzahrani, Abdulaziz, Almutairi, Mubarak, Amjad, Juwaria, Liu, Hong, Sun, Yonghu, Sun, Lele, Zhang, Huimin, Meng, Xiaoli ORCID: 0000-0002-7774-2075
et al (show 7 more authors) (2019) Dapsone‐ and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B*13:01. Allergy, 74 (8). pp. 1533-1548.


Ogese, Monday O ORCID: 0000-0002-1873-4032, Lister, Adam, Gardner, Joshua, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Alfirevic, Ana ORCID: 0000-0002-2801-9817, Pirmohamed, Munir ORCID: 0000-0002-7534-7266, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2021) Deciphering Adverse Drug Reactions: <i>In Vitro</i> Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01. TOXICOLOGICAL SCIENCES, 183 (1). pp. 139-153.


Ali, Serat-E ORCID: 0000-0002-9806-8796, Waddington, James C ORCID: 0000-0003-2641-5055, Park, B Kevin ORCID: 0000-0001-8384-824X and Meng, Xiaoli ORCID: 0000-0002-7774-2075
(2020) Definition of the Chemical and Immunological Signals Involved in Drug-Induced Liver Injury. CHEMICAL RESEARCH IN TOXICOLOGY, 33 (1). pp. 61-76.


Usui, Toru, Whitaker, Paul, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Watson, John, Antoine, Daniel J, French, Neil S ORCID: 0000-0002-9376-3482, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2016) Detection of Drug-Responsive T-Lymphocytes in a Case of Fatal Antituberculosis Drug-Related Liver Injury. CHEMICAL RESEARCH IN TOXICOLOGY, 29 (11). pp. 1793-1795.


Ali, Serat-E, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Kafu, Laila, Hammond, Sean, Zhao, Qing, Ogese, Monday ORCID: 0000-0002-1873-4032, Sison-Young, Rowena, Jones, Robert ORCID: 0000-0001-5608-001X, Chan, Benjamin, Livoti, Lucia
et al (show 7 more authors) (2023) Detection of Hepatic Drug Metabolite-Specific T-Cell Responses Using a Human Hepatocyte, Immune Cell Coculture System. CHEMICAL RESEARCH IN TOXICOLOGY, 36 (3). pp. 390-401.


Adair, Kareena ORCID: 0000-0001-9884-2094, Meng, Xiaoli ORCID: 0000-0002-7774-2075 and Naisbitt, Dean J
(2021) Drug hapten-specific T-cell activation: Current status and unanswered questions. PROTEOMICS, 21 (17-18). e2000267-.


Thomson, Paul J ORCID: 0000-0001-5431-0459, Kafu, Laila, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Snoeys, Jan, De Bondt, An, De Maeyer, Dries, Wils, Hans, Leclercq, Laurent, Vinken, Petra and Naisbitt, Dean J
(2021) Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat. ALLERGY, 76 (6). pp. 1825-1835.


Yip, Vincent LM ORCID: 0000-0003-1640-2816, Pertinez, Henry, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Maggs, James L, Carr, Daniel F, Park, B Kevin ORCID: 0000-0001-8384-824X, Marson, Anthony G ORCID: 0000-0002-6861-8806 and Pirmohamed, Munir ORCID: 0000-0002-7534-7266
(2021) Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87 (6). pp. 2572-2588.


Ogese, Monday O ORCID: 0000-0002-1873-4032, Jenkins, Rosalind E, Adair, Kareena ORCID: 0000-0001-9884-2094, Tailor, Arun, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Faulkner, Lee L, Enyindah, Bright O, Schofield, Amy, Diaz-Nieto, R, Ressel, Lorenzo ORCID: 0000-0002-6614-1223
et al (show 6 more authors) (2019) Exosomal transport of hepatocyte-derived drug-modified proteins to the immune system. Hepatology, 70 (5). pp. 1732-1749.


Waddington, James ORCID: 0000-0003-2641-5055
(2019) Flucloxacillin Protein Binding Leads to the Presentation of Novel MHC Peptides. PhD thesis, University of Liverpool.


Zhao, Qing, Almutairi, Mubarak, Tailor, Arun, Lister, Adam, Harper, Nicolas, Line, James ORCID: 0000-0003-3568-8928, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Pratoomwun, Jirawat, Jaruthamsophon, Kanoot ORCID: 0000-0003-1563-0024, Sukasem, Chonlaphat
et al (show 10 more authors) (2021) HLA Class-II. Restricted CD8<SUP>+</SUP> T Cells Contribute to the Promiscuous Immune Response in Dapsone-Hypersensitive Patients. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 141 (10). 2412-+.


Tailor, Arun, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Adair, Kareena ORCID: 0000-0001-9884-2094, Farrell, John ORCID: 0000-0002-8726-5997, Waddington, James C ORCID: 0000-0003-2641-5055, Daly, Ann, Pirmohamed, Munir ORCID: 0000-0002-7534-7266, Dear, Gordon, Park, B Kevin ORCID: 0000-0001-8384-824X and Naisbitt, Dean J
(2020) HLA DaB1*15:01-DQB1*06:02-Restricted Human CD4+T Cells Are Selectively Activated With Amoxicillin-Peptide Adducts. TOXICOLOGICAL SCIENCES, 178 (1). pp. 115-126.


Zhang, Yuan, Grice, Sophie, Wang, Na, Liu, Yongxia, Zhao, Qing, Liu, Tingting, Sun, Lele, Mi, Zihao, Wang, Jianwen, Yu, Gongqi
et al (show 6 more authors) (2023) HLA-C*15:02 and epidermal growth factor receptor inhibitor-induced erosive pustular dermatosis of the scalp. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 48 (11). pp. 1260-1265.


Waddington, James C ORCID: 0000-0003-2641-5055, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Illing, Patricia T, Tailor, Arun, Adair, Kareena ORCID: 0000-0001-9884-2094, Whitaker, Paul, Hamlett, Jane, Jenkins, Rosalind E, Farrell, John ORCID: 0000-0002-8726-5997, Berry, Neil ORCID: 0000-0003-1928-0738
et al (show 3 more authors) (2020) Identification of Flucloxacillin-Haptenated HLA-B*57:01 Ligands: Evidence of Antigen Processing and Presentation. TOXICOLOGICAL SCIENCES, 177 (2). pp. 454-465.


Ali, Serat-E, Waddington, James C, Lister, Adam, Sison-Young, Rowena, Jones, Robert P ORCID: 0000-0001-5608-001X, Rehman, Adeeb H, Goldring, Chris EP, Naisbitt, Dean J and Meng, Xiaoli ORCID: 0000-0002-7774-2075
(2023) Identification of flucloxacillin-modified hepatocellular proteins: implications in flucloxacillin-induced liver injury. TOXICOLOGICAL SCIENCES, 192 (1). pp. 106-116.


Waddington, James C ORCID: 0000-0003-2641-5055, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Naisbitt, Dean J and Park, B Kevin ORCID: 0000-0001-8384-824X
(2018) Immune drug-induced liver disease and drugs. Current Opinion in Toxicology, 10. pp. 46-53.


Naisbitt, Dean J, Olsson-Brown, Anna, Gibson, Andrew, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Ogese, Monday O ORCID: 0000-0002-1873-4032, Tailor, Arun ORCID: 0000-0002-9698-3480 and Thomson, Paul ORCID: 0000-0001-5431-0459
(2020) Immune dysregulation increases the incidence of delayed-type drug hypersensitivity reactions. ALLERGY, 75 (4). pp. 781-797.


Meng, Xiaoli ORCID: 0000-0002-7774-2075, Ariza, Adriana, Waddington, James ORCID: 0000-0003-2641-5055, Park, Kevin and Naisbitt, Dean
(2016) Immunological Mechanisms of Drug Hypersensitivity. CURRENT PHARMACEUTICAL DESIGN, 22 (45). pp. 6734-6747.


Amporndanai, Kangsa, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Shang, Weijuan, Jin, Zhenmig, Zhao, Yao, Rao, Zihe, Liu, Zhi-Jie, Yang, Haitao, Zhang, Leike, O'Neill, Paul M ORCID: 0000-0003-4338-0317
et al (show 2 more authors) (2021) Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. NATURE COMMUNICATIONS, 12 (1). 3061-.


Tailor, Arun ORCID: 0000-0002-9698-3480, Waddington, James C ORCID: 0000-0003-2641-5055, Meng, Xiaoli ORCID: 0000-0002-7774-2075 and Park, B Kevin ORCID: 0000-0001-8384-824X
(2016) Mass Spectrometric and Functional Aspects of Drug-Protein Conjugation. CHEMICAL RESEARCH IN TOXICOLOGY, 29 (12). pp. 1912-1935.


Ogese, Monday O ORCID: 0000-0002-1873-4032, Ahmed, Shaheda, Alferivic, Ana, Betts, Catherine J, Dickinson, Anne, Faulkner, Lee, French, Neil ORCID: 0000-0002-9376-3482, Gibson, Andrew, Hirschfield, Gideon M, Kammuller, Michael
et al (show 10 more authors) (2017) New Approaches to Investigate Drug-Induced Hypersensitivity. CHEMICAL RESEARCH IN TOXICOLOGY, 30 (1). pp. 239-259.


Faulkner, Lee, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Naisbitt, Dean J, Spraggs, Colin F and Park, B Kevin ORCID: 0000-0001-8384-824X
(2016) No Evidence for Drug-Specific Activation of Circulating T Cells from Patients with <i>HLA</i>-<i>DRB1</i>*07:01-Restricted Lapatinib-Induced Liver Injury. CHEMICAL RESEARCH IN TOXICOLOGY, 29 (12). pp. 2111-2113.


Thomson, Paul ORCID: 0000-0001-5431-0459, Fragkas, Nik, Kafu, Laila M, Aithal, Guruprasad P, Lucena, M Isabel, Terracciano, Luigi, Meng, Xiaoli, Pirmohamed, Munir, Brees, Dominique, Kullak‐Ublick, Gerd A
et al (show 4 more authors) (2024) Patients with <scp>naproxen‐induced</scp> liver injury display T‐cell memory responses toward an oxidative (S)‐<scp>O‐Desmethyl</scp> Naproxen metabolite but not the acyl glucuronide. Allergy, 79 (1). pp. 200-214.


Yaseen, Fiazia S, Saide, Katy, Kim, Seung-Hyun, Monshi, Manal, Tailor, Arun ORCID: 0000-0002-9698-3480, Wood, Sally, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Jenkins, Rosalind, Faulkner, Lee, Daly, Ann K
et al (show 3 more authors) (2015) Promiscuous T-cell responses to drugs and drug-haptens. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 136 (2). 474-+.


Penman, Sophie L ORCID: 0000-0001-5326-1675, Kiy, Robyn T ORCID: 0000-0001-7960-7283, Jensen, Rebecca L ORCID: 0000-0003-1134-2869, Beoku‐Betts, Christopher, Alfirevic, Ana ORCID: 0000-0002-2801-9817, Back, David, Khoo, Saye H, Owen, Andrew ORCID: 0000-0002-9819-7651, Pirmohamed, Munir ORCID: 0000-0002-7534-7266, Park, B Kevin ORCID: 0000-0001-8384-824X
et al (show 3 more authors) (2020) Safety perspectives on presently considered drugs for the treatment of COVID‐19. British Journal of Pharmacology, 177 (19). pp. 4353-4374.


Ariza, Adriana, Jaruthamsophon, Kanoot, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Labella, Marina, Adair, Kareena ORCID: 0000-0001-9884-2094, Tailor, Arun, Sukasem, Chonlaphat, Whitaker, Paul, Peckham, Daniel, Pirmohamed, Munir ORCID: 0000-0002-7534-7266
et al (show 2 more authors) (2022) Shared Clavulanate and Tazobactam Antigenic Determinants Activate T-Cells from Hypersensitive Patients. CHEMICAL RESEARCH IN TOXICOLOGY, 35 (11). pp. 2122-2132.


Thomson, Paul ORCID: 0000-0001-5431-0459, Hammond, Sean, Meng, Xiaoli ORCID: 0000-0002-7774-2075 and Naisbitt, Dean J
(2023) What’s been Hapten-ing over the last 88 years? Medicinal Chemistry Research, 32 (9). pp. 1950-1971.


Line, James ORCID: 0000-0003-3568-8928, Saville, Eleanor, Meng, Xiaoli ORCID: 0000-0002-7774-2075 and Naisbitt, Dean
(2023) Why drug exposure is frequently associated with T-cell mediated cutaneous hypersensitivity reactions. FRONTIERS IN TOXICOLOGY, 5. 1268107-.


Ogese, Monday O ORCID: 0000-0002-1873-4032, Lister, Adam, Farrell, Liam, Gardner, Joshua, Kafu, Laila, Ali, Serat-E, Gibson, Andrew, Hillegas, Aimee, Meng, Xiaoli ORCID: 0000-0002-7774-2075, Pirmohamed, Munir ORCID: 0000-0002-7534-7266
et al (show 3 more authors) (2023) A blinded in vitro analysis of the intrinsic immunogenicity of hepatotoxic drugs: implications for preclinical risk assessment. TOXICOLOGICAL SCIENCES, 197 (1). pp. 38-52.


Adair, Kareena ORCID: 0000-0001-9884-2094
(2022) The role of drug-protein haptenation in β-lactam hypersensitivity. PhD thesis, University of Liverpool.

This list was generated on Sat Apr 13 20:18:43 2024 BST.